Trichoplein, Keratin Filament Binding Protéines (TCHP)

May act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery.

afficher tous les protéines Gène GeneID UniProt
Humain TCHP TCHP 84260 Q9BT92
Souris TCHP TCHP 77832 Q3TVW5
Rat TCHP TCHP 304547  
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Showing 5 out of 5 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Escherichia coli (E. coli) Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 30 to 35 Days
$4,744.22
Détails
Escherichia coli (E. coli) Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 30 to 35 Days
$4,744.22
Détails
Levure Xenopus laevis His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$3,415.50
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Levure Poisson Zèbre His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$3,415.50
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Escherichia coli (E. coli) Humain His-SUMO Tag   100 μg Connectez-vous pour afficher 11 Days
$411.40
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Plus protéines pour Trichoplein, Keratin Filament Binding (TCHP) partenaires d'interaction

Human Trichoplein, Keratin Filament Binding (TCHP) interaction partners

  1. Ndel1 (Montrer NDEL1 Protéines) acts as a novel upstream regulator of the trichoplein-Aurora A (Montrer AURKA Protéines) pathway to inhibit primary cilia assembly.

  2. These findings underscore the complexity of PGC-1alpha-mediated mitochondrial homeostasis and establish mitostatin as a key regulator of tumor cell mitophagy and angiostasis.

  3. Trichoplein controls microtubule anchoring at the centrosome by binding to Odf2 (Montrer ODF1 Protéines) and ninein (Montrer NIN Protéines).

  4. Trichoplein/mitostatin is a new regulator of mitochondria-endoplasmic reticulum juxtaposition.

  5. MITOSTATIN was found within a 3.2-kb transcript for an approximately 62 kDa mitochondrial protein (Montrer COX6B2 Protéines) with tumor suppressor activity. It inhibits cell growth, is proapoptotic and downregulates Hsp27 (Montrer HSPB1 Protéines).

  6. trichoplein is a keratin 8/18-binding protein that may be involved in the organization of the apical network of keratin filaments and desmosomes in simple epithelial cells

Mouse (Murine) Trichoplein, Keratin Filament Binding (TCHP) interaction partners

  1. Ndel1 (Montrer NDEL1 Protéines) acts as a novel upstream regulator of the trichoplein-Aurora A (Montrer AURKA Protéines) pathway to inhibit primary cilia assembly.

  2. MITOSTATIN may acts as a tumor suppressor gene in prostate cancer.

Profil protéine Trichoplein, Keratin Filament Binding (TCHP)

Profil protéine

May act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. May regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells (By similarity).

Gene names and symbols associated with TCHP

  • trichoplein keratin filament binding (TCHP)
  • trichoplein, keratin filament binding (tchp)
  • trichoplein, keratin filament binding (Tchp)
  • trichoplein, keratin filament binding (TCHP)
  • trichoplein, keratin filament binding L homeolog (tchp.L)
  • A930031F18Rik Protéine
  • AV279199 Protéine
  • RGD1310813 Protéine
  • TpMs Protéine
  • zgc:136634 Protéine

Protein level used designations for TCHP

trichoplein, keratin filament binding , mitochondrial protein with oncostatic activity , mitostatin , trichoplein keratin filament-binding protein , tumor suppressor protein

GENE ID SPECIES
100059689 Equus caballus
452226 Pan troglodytes
100171790 Pongo abelii
100379712 Xenopus (Silurana) tropicalis
100595470 Nomascus leucogenys
84260 Homo sapiens
77832 Mus musculus
304547 Rattus norvegicus
477521 Canis lupus familiaris
100518693 Sus scrofa
522380 Bos taurus
398528 Xenopus laevis
678595 Danio rerio
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