Tripartite Motif Containing 25 (TRIM25) Kits ELISA

The protein encoded by TRIM25 is a member of the tripartite motif (TRIM) family. De plus, nous expédions TRIM25 Anticorps (149) et TRIM25 Protéines (5) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
TRIM25 7706 Q14258
Anti-Souris TRIM25 TRIM25 217069 Q61510
Anti-Rat TRIM25 TRIM25 494338  
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Catalogue No. Reactivité Sensibilité Gamme Images Quantité Fournisseur Livraison Prix Détails
Humain < 0.188 ng/mL 0.313 ng/mL - 20 ng/mL   96 Tests Connectez-vous pour afficher 11 to 18 Days
  96 Tests Connectez-vous pour afficher 2 to 3 Days

Plus Kits ELISA pour TRIM25 partenaires d'interaction

Human Tripartite Motif Containing 25 (TRIM25) interaction partners

  1. The RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain, which we postulate to be a novel RNA-binding domain.

  2. TRIM25 inhibits hepatocellular carcinoma progression by targeting MTA1 (Montrer MTA1 Kits ELISA).

  3. TRIM25 is a key determinant of breast cancer metastasis.

  4. V interaction with TRIM25 and RIG-I (Montrer DDX58 Kits ELISA) prevents TRIM25-mediated ubiquitination of RIG-I (Montrer DDX58 Kits ELISA) and disrupts downstream RIG-I (Montrer DDX58 Kits ELISA) signaling to the mitochondrial antiviral signaling protein (Montrer MAVS Kits ELISA).

  5. HPV E6 oncoprotein antagonizes the activation of the cytoplasmic innate immune sensor RIG-I (Montrer DDX58 Kits ELISA) by targeting its upstream regulatory enzymes TRIM25 and USP15. We further show that the RIG-I (Montrer DDX58 Kits ELISA) signaling cascade is important for an antiviral innate immune response to HPV16 infection

  6. this study shows thatTRIM25 targets ERG (Montrer ERG Kits ELISA) for degradation in prostate cancer

  7. TRIM25 actively participates in higher-order assembly of the RIG-I (Montrer DDX58 Kits ELISA) signalosome.

  8. Our results indicate that TRIM25 is associated with cisplatin resistance and 14-3-3sigma-MDM2 (Montrer MDM2 Kits ELISA)-p53 (Montrer TP53 Kits ELISA) signaling pathway is involved in this process, suggesting targeting TRIM25 may be a potential strategy for the reversal of cisplatin resistance.

  9. expression of TRIM25 might be critical for lung cancer cell migration, proliferation as well as doxorubicin resistance.

  10. Disturbed p53 (Montrer TP53 Kits ELISA)-MDM2 (Montrer MDM2 Kits ELISA) feedback loop contributing to the pathogenesis of thoracic aortic dissection may be linked to TRIM25 overexpression.

Mouse (Murine) Tripartite Motif Containing 25 (TRIM25) interaction partners

  1. TRIM25 as a key determinant of breast cancer metastasis.

  2. Studies indicated that mice with disrupted Trim25 were viable and fertile, uterine response to oestrogen was greatly attenuated and the uteri were underdeveloped.

  3. Two key residues (Asp (Montrer C3 Kits ELISA)(488) and Trp (Montrer TYRP1 Kits ELISA)(621)) in the TRIM25 B30.2 domain are critical for binding to the RIG-I (Montrer DDX58 Kits ELISA) CARDs.

  4. Two well-known E3 ubiquitin ligases, Trim25 (also called Efp) and Trim71 (also called Lin41), are validated as RNA-binding proteins, revealing a potential link between RNA biology and protein-modification pathways.

TRIM25 profil antigène

Antigen Summary

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.

Gene names and symbols associated with TRIM25

  • E3 ubiquitin/ISG15 ligase TRIM25 (LOC100146440) anticorps
  • tripartite motif containing 25 (trim25) anticorps
  • E3 ubiquitin/ISG15 ligase TRIM25-like L homeolog (LOC100490741.L) anticorps
  • tripartite motif containing 25 (TRIM25) anticorps
  • microRNA 3614 (MIR3614) anticorps
  • tripartite motif-containing 25 (Trim25) anticorps
  • AA960166 anticorps
  • AL022677 anticorps
  • Efp anticorps
  • MGC130751 anticorps
  • RNF147 anticorps
  • Z147 anticorps
  • Zfp147 anticorps
  • zgc:55773 anticorps
  • Znf147 anticorps

Protein level used designations for TRIM25

tripartite motif-containing 25 , E3 ubiquitin/ISG15 ligase TRIM25 , tripartite motif containing 25 , RING finger protein 147 , estrogen-responsive finger protein , tripartite motif protein TRIM25 , tripartite motif-containing protein 25 , ubiquitin/ISG15-conjugating enzyme TRIM25 , zinc finger protein 147 (estrogen-responsive finger protein) , zinc finger protein-147 , tripartite motif protein 25 , zinc finger protein 147

100146440 Equus caballus
393144 Danio rerio
431932 Xenopus laevis
455146 Pan troglodytes
100013883 Monodelphis domestica
100127751 Xenopus (Silurana) tropicalis
100440167 Pongo abelii
100599729 Nomascus leucogenys
7706 Homo sapiens
417401 Gallus gallus
510923 Bos taurus
491103 Canis lupus familiaris
217069 Mus musculus
494338 Rattus norvegicus
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