Tripartite Motif Containing 8 (TRIM8) Kits ELISA

The protein encoded by TRIM8 is a member of the tripartite motif (TRIM) family. De plus, nous expédions TRIM8 Anticorps (45) et TRIM8 Protéines (4) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
Anti-Humain TRIM8 TRIM8 81603 Q9BZR9
Anti-Souris TRIM8 TRIM8 93679 Q99PJ2
Anti-Rat TRIM8 TRIM8 688785  
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Plus Kits ELISA pour TRIM8 partenaires d'interaction

Human Tripartite Motif Containing 8 (TRIM8) interaction partners

  1. TRIM8 activates STAT3 (Montrer STAT3 Kits ELISA) by suppressing the expression of PIAS3 (Montrer PIAS3 Kits ELISA), an inhibitor of STAT3 (Montrer STAT3 Kits ELISA), most likely through E3-mediated ubiquitination and proteasomal degradation.

  2. we provided evidence that TRIM8 and its regulators miR-17-5p and miR (Montrer MLXIP Kits ELISA)-106b-5 participate to a feedback loop controlling cell proliferation through the reciprocal modulation of p53 (Montrer TP53 Kits ELISA), miR (Montrer MLXIP Kits ELISA)-34a and N-MYC (Montrer MYCN Kits ELISA).

  3. A pathogenic effect of a heterozygous truncating mutation in the tripartite motif containing 8 (TRIM8) gene on the postnatal development of the human brain.

  4. Our study provides evidences that TRIM8 may participate in the carcinogenesis and progression of glioma and that the transcriptional repression of TRIM8 might have potential value for predicting poor prognosis in glioma patients.

  5. These findings provide the first mechanistic link between TRIM8 and the drug resistance of clear cell Renal Cell Carcinoma

  6. Nucleo-cytoplasmic trafficking of TRIM8, a novel oncogene (Montrer RAB1A Kits ELISA), is involved in positive regulation of TNF (Montrer TNF Kits ELISA) induced NF-kappaB (Montrer NFKB1 Kits ELISA) pathway.

  7. TRIM8 is a p53 (Montrer TP53 Kits ELISA) direct target gene that induces p53 (Montrer TP53 Kits ELISA) stabilization and promotes the degradation of MDM2 (Montrer MDM2 Kits ELISA) protein.

  8. Tripartite motif 8 (TRIM8) modulates TNFalpha (Montrer TNF Kits ELISA)- and IL-1beta (Montrer IL1B Kits ELISA)-triggered NF-kappaB (Montrer NFKB1 Kits ELISA) activation by targeting TAK1 (Montrer MAP3K7 Kits ELISA) for K63-linked polyubiquitination.

  9. TRIM8 modulates translocation of phosphorylated STAT3 into the nucleus through interaction with Hsp90beta and consequently regulates transcription of Nanog in embryonic stem cells.

  10. These findings indicate that TRIM8 enhances the STAT3 (Montrer STAT3 Kits ELISA)-dependent signal pathway by inhibiting the function of PIAS3 (Montrer PIAS3 Kits ELISA).

Mouse (Murine) Tripartite Motif Containing 8 (TRIM8) interaction partners

  1. these studies reveal an additional regulatory function of TRIM8 in innate immune responses: TRIM8 catalyzes polyubiquitination of TRIF (Montrer RNF138 Kits ELISA), resulting in disruption of TRIF (Montrer RNF138 Kits ELISA)-TBK1 (Montrer TBK1 Kits ELISA) interaction

  2. TRIM8 plays a deleterious role in pressure overload-induced cardiac hypertrophy by accelerating the activation of TAK1 (Montrer NR2C2 Kits ELISA)-dependent signaling pathways.

  3. potent regulator that exacerbates steatohepatitis and metabolic disorders dependent on its binding and ubiquitinating capacity on transforming growth factor-beta-activated kinase 1 (Montrer MAP3K7 Kits ELISA)

  4. TRIM8 has pro-inflammatory effect on Pseudomonas aeruginosa -induced keratitis

  5. Gerp transcribes interferon-gamma (Montrer IFNG Kits ELISA) in epithelial and lymphoid cells and is expressed almost ubiquitously in tissues.

TRIM8 profil antigène

Antigen Summary

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to nuclear bodies. Its structure is similar to some tumor suppressor proteins and its gene maps to a locus thought to contain tumor suppressor genes.

Gene names and symbols associated with TRIM8

  • tripartite motif containing 8 (TRIM8) anticorps
  • tripartite motif containing 8 L homeolog (trim8.L) anticorps
  • tripartite motif-containing 8 (Trim8) anticorps
  • tripartite motif containing 8b (trim8b) anticorps
  • AA408830 anticorps
  • BB006755 anticorps
  • GERP anticorps
  • Rnf27 anticorps
  • si:ch211-208d15.5 anticorps
  • wu:fc90g07 anticorps

Protein level used designations for TRIM8

glioblastoma expressed ring finger protein , glioblastoma-expressed RING finger protein , probable E3 ubiquitin-protein ligase TRIM8 , ring finger protein 27 , tripartite motif protein TRIM8 , tripartite motif-containing 8 , tripartite motif-containing protein 8 , tripartite motif protein 8

81603 Homo sapiens
423864 Gallus gallus
486863 Canis lupus familiaris
782444 Bos taurus
100127258 Xenopus laevis
93679 Mus musculus
688785 Rattus norvegicus
559967 Danio rerio
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