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TUSC2 is a highly conserved lung cancer candidate gene. De plus, nous expédions Tumor Suppressor Candidate 2 Protéines (3) et Tumor Suppressor Candidate 2 Kits (1) et beaucoup plus de produits pour cette protéine.
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Human Polyclonal TUSC2 Primary Antibody pour ELISA - ABIN451824
Deng, Kawashima, Wu, Jayachandran, Xu, Minna, Roth, Ji et al.: Synergistic tumor suppression by coexpression of FUS1 and p53 is associated with down-regulation of murine double minute-2 and activation of the apoptotic protease-activating factor 1-dependent ... dans Cancer research 2007
FOXP1 (Montrer FOXP1 Anticorps), TP53INP1 (Montrer TP53INP1 Anticorps), TNFAIP3 (Montrer TNFAIP3 Anticorps), and TUSC2 were identified as miR (Montrer MLXIP Anticorps)-19a targets.
The therapeutic activity of TUSC2 could extend the use of erlotinib to lung cancer patients with wildtype EGFR (Montrer EGFR Anticorps).
TUSC2P and TUSC2 3'-UTR (Montrer UTS2R Anticorps) expression inhibits cell proliferation, survival, migration, invasion and colony formation, and increases tumor cell death. TUSC2P and TUSC2 3'-UTR (Montrer UTS2R Anticorps) bind to miRNAs and arrest their functions, leading to increased TUSC2 translation.
The tumor suppressor gene TUSC2 (FUS1) sensitizes NSCLC to the AKT (Montrer AKT1 Anticorps) inhibitor MK2206 in LKB1 (Montrer STK11 Anticorps)-dependent manner.
RNA sequence elements in FUS1 (Montrer FUS Anticorps) UTRs that regulate FUS1 (Montrer FUS Anticorps) protein express were identified.
Absence of tumor suppressor FUS1 (Montrer FUS Anticorps) protein expression is associated with bone and soft tissue sarcomas.
Data show that the recombinant FUS1 (Montrer FUS Anticorps) plasmid has been successfully cloned, which allows highly efficient FUS1 (Montrer FUS Anticorps) expression in E.coli strain Rosetta (DE3)2 plys.
The goal of this study was to analyze possible involvement of TUSC2 in malignant pleural mesothelioma.
Myristoylation is required for Fus1 (Montrer FUS Anticorps)-mediated tumor-suppressing activity and suggest a novel mechanism for the inactivation of tumor suppressors in lung cancer.
These results suggest that miR (Montrer MLXIP Anticorps)-378 enhances cell survival, tumor growth, and angiogenesis through repression of the expression of two tumor suppressors, Sufu (Montrer SUFUH Anticorps) and Fus-1 (Montrer FUS Anticorps).
Fus1 achieves its protective role in inflammation, autoimmunity, and cancer via the regulation of mitochondrial calcium and calcium-coupled parameters.
This gene is a highly conserved lung cancer candidate gene. No other information about this gene is currently available.
tumor suppressor candidate 2
, PDGFA associated protein 2
, PDGFA-associated protein 2
, fus-1 protein
, fusion 1 protein
, lung cancer candidiate, FUS