anti-Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L) Anticorps

The protein encoded by UFD1L forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. De plus, nous expédions Ubiquitin Fusion Degradation Protein 1 Homolog Protéines (10) et Ubiquitin Fusion Degradation Protein 1 Homolog Kits (2) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
UFD1L 7353 Q92890
UFD1L 22230 P70362
UFD1L 84478 Q9ES53
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Top anti-Ubiquitin Fusion Degradation Protein 1 Homolog Anticorps sur anticorps-enligne.fr

Showing 10 out of 87 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-UFD1L Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: MCF7 cell lysate UFD1L is supported by BioGPS gene expression data to be expressed in MCF7 100 μL 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué ICC, IF, IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded H441 xenograft, using UFD1L, antibody at 1:500 dilution. WB Image UFD1L antibody detects UFD1L protein by Western blot analysis. A. 50 µg mouse lung lysate/extract 12 % SDS-PAGE UFD1L antibody , dilution: 1:1000 100 μL 3 to 4 Days
$466.18
Détails
Humain Souris Inconjugué ELISA, FACS, ICC, IHC, WB Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng) Western blot analysis using UFD1L mAb against human UFD1L (AA: 208-307) recombinant protein. (Expected MW is 36.8 kDa) 0.1 mg 3 to 4 Days
$430.10
Détails
Humain Lapin Inconjugué IHC, WB Western blot analysis of UFD1L expression in Jurkat (A), A431 (B), mouse heart (C), rat brain (D) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Détails
Chien Lapin Inconjugué WB 100 μL 11 to 14 Days
$551.83
Détails
Humain Souris Inconjugué Fig. 1. Figure 1:Black line: Control Antigen (100 ng)Purple line: Antigen (10ng) 100 μg 11 to 16 Days
$469.05
Détails
Humain Lapin Inconjugué IF/ICC, WB Western blot analysis of extracts of various cell lines, using UFD1L antibody (ABIN5974111) at 1/1000 dilution. 100 μL 11 to 16 Days
$426.40
Détails
Humain Lapin Inconjugué ICC, IHC, IHC (p), WB   100 μL 11 to 14 Days
$537.17
Détails
Humain Lapin Inconjugué IHC, WB Western blot analysis of extracts of various cell lines, using UFD1L antibody. Immunohistochemistry of paraffin-embedded human colon using UFD1L antibody. 200 μL 12 to 14 Days
$438.90
Détails
Humain Lapin Inconjugué WB Western blot analysis of extracts of various cell lines, using UFD1L antibody. 200 μL 12 to 14 Days
$438.90
Détails

anti-Ubiquitin Fusion Degradation Protein 1 Homolog Anticorps mieux référencés

  1. Human Polyclonal UFD1L Primary Antibody pour IP, WB - ABIN315864 : Guo, Qi: VCP cooperates with UBXD1 to degrade mitochondrial outer membrane protein MCL1 in model of Huntington's disease. dans Biochimica et biophysica acta 2016 (PubMed)

Plus d’anticorps contre Ubiquitin Fusion Degradation Protein 1 Homolog partenaires d’interaction

Human Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L) interaction partners

  1. CHOP inactivation or BCL2 overexpression is sufficient to rescue tumor cell apoptosis induced by UFD1 knockdown.

  2. We demonstrate that WT p97 can unfold proteins and that this activity is dependent on the p97 adaptor NPLOC4-UFD1L, ATP hydrolysis, and substrate ubiquitination, with branched chains providing maximal stimulation.

  3. The study revealed a regulatory role of the p97-Npl4-Ufd1 complex in regulating a partial degradation of the NF-kappaB subunit p100.

  4. p97-Ufd1-Npl4 is an integral part of G2/M checkpoint signaling and thereby suppresses chromosome instability.

  5. Data indicate that the p97-UFD1L-NPL4 protein complex specifically associates with ubiquitinated IkappaBalpha via the interactions between p97 and the SCF(beta-TRCP) ubiquitin ligase.

  6. This study demonistrated that UFD1L may participate in the core cognitive deficits observed in schizophrenia.

  7. In coordination with the P97-UFD1-NPL4 complex (P97(UFD1/NPL4)), NUB1L promotes transfer of NEDD8 to proteasome for degradation.

  8. increased corpus callosum volume in children with 22q11DS is associated with UFD1L polymorphism.

  9. Data indicate that Npl4-Ufd1 heterodimer is required for VCP-FAF1 interaction.

  10. Data establish Cdc48/p97-Ufd1-Npl4 as a crucial negative regulator of Aurora B early in mitosis of human somatic cells and suggest that the activity of Aurora B on chromosomes needs to be restrained to ensure faithful chromosome segregation.

  11. Ubiquitin-recognition protein Ufd1 couples the endoplasmic reticulum (ER) stress response to cell cycle control

  12. This study suggested that AA genotype of UFD1L gene, which is involved in neurodevelopmental processes, may contribute to early-onset schizophrenia. Therefore, rs5992403 polymorphism may not be a risk factor for schizophrenia.

  13. Data suggest that the human cytomegalovirus dislocation reaction in US2 cells is independent of the p97 cofactor Ufd1-Npl4, and different retrotranslocation mechanisms can employ distinct p97 ATPase complexes to dislocate substrates.

  14. a functional analysis of its 5' regulatory region

  15. Ufd1l is localized around the nucleus and it does not interfere with Fas-and ceramide-mediated apoptosis.

  16. Ufd1-nuclear protein localization 4 is a negative regulator of retrotranslocation, delaying the retrotranslocation of endoplasmic reticulum-associated degradation substrates independently of its association with VCP

  17. This study identifies Ufd1 as a cofactor of gp78, reveals an unappreciated function of Ufd1 in the ubiquitination reaction during endoplasmic reticulum -associated degradation, and illustrates that Ufd1 plays a critical role in cholesterol metabolism.

  18. allelic associations of the UFD1L locus identified; 4-SNP haplotype analysis showed strong association with schizophrenia; possibility that a disease-resistant variant may be carried by two or more haplotypes due to frequent recombination during meiosis.

  19. This favors the model where the Ufd1-Npl4 dimer forms a regulatory gate at the exit from the retrotranslocone, rather than actively promoting retrotranslocation like the p97VCP ATPase.

Mouse (Murine) Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L) interaction partners

  1. The study revealed a regulatory role of the p97-Npl4-Ufd1 complex in regulating a partial degradation of the NF-kappaB subunit p100.

  2. the p97-Ufd1-Npl4 complex couples ubiquitinated IP(3) receptors to proteasomal degradation and, thus, plays a key role in IP(3) receptor processing

  3. structural analysis of the p97-Npl4-Ufd1 interface

Caenorhabditis elegans (C. elegans) Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L) interaction partners

  1. These findings identified a role for CDC-48(UFD-1/NPL-4) in DNA replication, which is important for cell cycle progression and genome stability.

Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L) profil antigène

Profil protéine

The protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18.

Gene names and symbols associated with UFD1L

  • ubiquitin recognition factor in ER associated degradation 1 (UFD1) anticorps
  • ubiquitin recognition factor in ER-associated degradation 1 (Ufd1) anticorps
  • ubiquitin recognition factor in ER associated degradation 1 (Ufd1) anticorps
  • ubiquitin fusion degradation 1 like (yeast) (UFD1L) anticorps
  • ubiquitin recognition factor in ER associated degradation 1 S homeolog (ufd1.S) anticorps
  • ubiquitin recognition factor in ER associated degradation 1 (ufd1l) anticorps
  • ubiquitin recognition factor in ER associated degradation 1 (ufd1) anticorps
  • ubiquitin fusion degradation protein 1 homolog (EHI_125920) anticorps
  • ubiquitin fusion degradation protein 1 homolog (LOC100166745) anticorps
  • ubiquitin fusion degradation protein 1 homolog (LOC100635687) anticorps
  • ubiquitin fusion degradation protein 1 homolog (LOC100648660) anticorps
  • Ubiquitin Fusion Degradation (yeast UFD homolog) (ufd-1) anticorps
  • ufd1 anticorps
  • Ufd1l anticorps
  • wu:fc55f04 anticorps
  • zgc:92341 anticorps

Protein level used designations for UFD1L

UB fusion protein 1 , ubiquitin fusion degradation protein 1 homolog , ubiquitin fusion degradation 1-like protein , fc55f04 , ubiquitin fusion degradation 1-like , ubiquitin fusion degradation 1 like (yeast) , ubiquitin fusion degradation 1 like

GENE ID SPECIES
7353 Homo sapiens
22230 Mus musculus
84478 Rattus norvegicus
374186 Gallus gallus
399034 Xenopus laevis
436724 Danio rerio
448516 Xenopus (Silurana) tropicalis
458650 Pan troglodytes
507124 Bos taurus
711716 Macaca mulatta
6219427 Entamoeba histolytica HM-1:IMSS
100166745 Acyrthosiphon pisum
100409073 Callithrix jacchus
100451821 Pongo abelii
100582577 Nomascus leucogenys
100635687 Amphimedon queenslandica
100648660 Bombus terrestris
100153062 Sus scrofa
608300 Canis lupus familiaris
3565860 Caenorhabditis elegans
100728094 Cavia porcellus
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