anti-Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) Anticorps

UBR2 encodes an E3 ubiquitin ligase of the N-end rule proteolytic pathway that targets proteins with destabilizing N-terminal residues for polyubiquitylation and proteasome-mediated degradation. De plus, nous expédions UBR2 Kits (2) et UBR2 Protéines (2) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
UBR2 23304 Q8IWV8
UBR2 224826 Q6WKZ8
UBR2 363188  
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Top anti-UBR2 Anticorps sur anticorps-enligne.fr

Showing 10 out of 60 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-UBR2 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:1562500  Positive Control:  MCF7 cell lysate There is BioGPS gene expression data showing that UBR2 is expressed in MCF7 Host:  Rabbit  Target Name:  UBR2  Sample Type:  Human Fetal Brain  Antibody Dilution:  1.0ug/ml 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué WB Western blot analysis of UBR2 expression in HepG2 (A), mouse liver (B), rat liver (C) whole cell lysates. 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Poulet Chèvre Inconjugué ELISA, IHC, IHC (p) Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Connectez-vous pour afficher 7 to 9 Days
$484.00
Détails
Cheval Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Souris Chèvre Inconjugué ELISA, WB Immunohistochemistry-Paraffin: UBR2 Antibody  - Staining of paraffin embedded Human Cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. 0.1 mg Connectez-vous pour afficher 7 to 9 Days
$373.75
Détails
Humain Souris Inconjugué IF, RNAi, ELISA, WB Western Blot analysis of UBR2 expression in transfected 293T cell line by UBR2 monoclonal antibody (M01), clone 4G4.<br><br>Lane 1: UBR2 transfected lysate(50 KDa).<br>Lane 2: Non-transfected lysate.<br> Western blot analysis of UBR2 over-expressed 293 cell line, cotransfected with UBR2 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with UBR2 monoclonal antibody (M01), clone 4G4. GAPDH ( 36.1 kDa ) used as specificity and loading control. 100 μg Connectez-vous pour afficher 11 to 12 Days
$440.00
Détails
Humain Chèvre Inconjugué ELISA, WB   100 μg Connectez-vous pour afficher 6 to 7 Days
$242.88
Détails
Rat Chèvre Inconjugué ELISA   0.1 mg Connectez-vous pour afficher 2 to 3 Days
$481.25
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: UBR2 Antibody  - Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & plasma membrane. Immunohistochemistry-Paraffin: UBR2 Antibody  - Staining of human smooth muscle shows strong cytoplasmic positivity. 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$491.63
Détails
Humain Souris Inconjugué ELISA, WB Western Blot analysis of UBR2 expression in transfected 293T cell line by UBR2 monoclonal antibody (M01A), clone 4G4.<br><br>Lane 1: UBR2 transfected lysate(50 KDa).<br>Lane 2: Non-transfected lysate.<br> Western Blot detection against Immunogen (36.74 KDa) . 200 μL Connectez-vous pour afficher 11 to 12 Days
$440.00
Détails

UBR2 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-UBR2 Anticorps mieux référencés

  1. Mouse (Murine) Polyclonal UBR2 Primary Antibody pour ELISA, WB - ABIN4250454 : Zenker, Mayerle, Lerch, Tagariello, Zerres, Durie, Beier, Hülskamp, Guzman, Rehder, Beemer, Hamel, Vanlieferinghen, Gershoni-Baruch, Vieira, Dumic, Auslender, Gil-da-Silva-Lopes, Steinlicht, Rauh et al.: Deficiency of UBR1, a ubiquitin ligase of the N-end rule pathway, causes pancreatic dysfunction, malformations and mental retardation (Johanson-Blizzard syndrome). ... dans Nature genetics 2005 (PubMed)
    Show all 5 Pubmed References

Plus d’anticorps contre UBR2 partenaires d’interaction

Human Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) interaction partners

  1. There was a significant difference between the oligospermia men (oligospermia group) and the fertile men (control group) observed in this research that could indicate that the combined AT-TC-CC genotype in the UBR2 gene (rs16895863, rs373341, rs3749897 respectively) is a possible risk of idiopathic oligospermia for men in Sichuan, China.

  2. The c.1,066A>T variant in the UBR2 gene is associated with increased susceptibility to azoospermia caused by meiotic arrest.

  3. Study provides functional data for the mouse ubiquitin protein ligase E3 component n-recognin 2 protein.

Mouse (Murine) Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) interaction partners

  1. Taken together, our findings indicated that p53 (Montrer TP53 Anticorps)(-/-) mBMMSC exosomes could deliver UBR2 to target cells and promote gastric cancer growth and metastasis by regulating Wnt (Montrer WNT2 Anticorps)/beta-catenin (Montrer CTNNB1 Anticorps) pathway.

  2. These data suggest that Tex19.1 and Ubr2 are required for mouse spermatocytes to accumulate sufficient Spo11 (Montrer SPO11 Anticorps)-dependent recombination to ensure that the homology search is consistently successful, and reveal a hitherto unknown genetic pathway promoting meiotic recombination in mammals.

  3. Results suggest that UBR2 up-regulation in cachectic muscle is mediated by the p38beta (Montrer MAPK11 Anticorps)-C/EBPbeta (Montrer CEBPB Anticorps) signaling pathway responsible for the bulk of tumor-induced muscle proteolysis.

  4. Results suggest that the binding of Ubr2 to Tex19.1 metabolically stabilizes Tex19.1 during spermatogenesis, revealing a new function for Ubr2 outside the conventional N-end rule pathway.

  5. insufficiency in UBR2-dependent histone ubiquitination triggers a pachytene checkpoint system, providing a new insight into chromatin remodeling and gene expression regulation

  6. UBR2 ubiquitin ligase and the N-end rule pathway are required for male meiosis and spermatogenesis and for an essential aspect of female embryonic development.

  7. mouse fibroblast cells derived from Ubr2 deficient embryos display genome instability.

  8. UBR1 (Montrer UBR1 Anticorps)-/-UBR2-/- embryos die at midgestation, with defects in neurogenesis and cardiovascular development.

UBR2 profil antigène

Profil protéine

This gene encodes an E3 ubiquitin ligase of the N-end rule proteolytic pathway that targets proteins with destabilizing N-terminal residues for polyubiquitylation and proteasome-mediated degradation. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with UBR2

  • ubiquitin protein ligase E3 component n-recognin 2 (UBR2) anticorps
  • ubiquitin protein ligase E3 component n-recognin 2 (ubr2) anticorps
  • ubiquitin protein ligase E3 component n-recognin 2 S homeolog (ubr2.S) anticorps
  • ubiquitin protein ligase E3 component n-recognin 2 (Ubr2) anticorps
  • 9930021A08Rik anticorps
  • AI462103 anticorps
  • AW540746 anticorps
  • bA49A4.1 anticorps
  • C6orf133 anticorps
  • dJ242G1.1 anticorps
  • dJ392M17.3 anticorps
  • E130209G04Rik anticorps
  • mKIAA0349 anticorps
  • RP3-392M17.3 anticorps
  • si:ch211-239i4.2 anticorps

Protein level used designations for UBR2

ubiquitin protein ligase E3 component n-recognin 2 , rp3-392m17.3 , E3 ubiquitin-protein ligase UBR2 , ubiquitin-protein ligase E3-alpha-2 , ubiquitin-protein ligase E3-alpha-II , N-recognin-2 , ubiquitin ligase E3 alpha-II

GENE ID SPECIES
100522688 Sus scrofa
100009912 Monodelphis domestica
100170193 Xenopus (Silurana) tropicalis
100542516 Meleagris gallopavo
559136 Danio rerio
734725 Xenopus laevis
421387 Gallus gallus
23304 Homo sapiens
474903 Canis lupus familiaris
527153 Bos taurus
224826 Mus musculus
363188 Rattus norvegicus
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