Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) Kits ELISA

UBR2 encodes an E3 ubiquitin ligase of the N-end rule proteolytic pathway that targets proteins with destabilizing N-terminal residues for polyubiquitylation and proteasome-mediated degradation. De plus, nous expédions UBR2 Anticorps (65) et UBR2 Protéines (2) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
UBR2 23304 Q8IWV8
Anti-Souris UBR2 UBR2 224826 Q6WKZ8
Anti-Rat UBR2 UBR2 363188  
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Catalogue No. Reactivité Sensibilité Gamme Images Quantité Livraison Prix Détails
Humain 0.078 ng/mL 0.312-20 ng/mL Typical standard curve 96 Tests 15 to 18 Days
$910.56
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Plus Kits ELISA pour UBR2 partenaires d'interaction

Human Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) interaction partners

  1. There was a significant difference between the oligospermia men (oligospermia group) and the fertile men (control group) observed in this research that could indicate that the combined AT-TC-CC genotype in the UBR2 gene (rs16895863, rs373341, rs3749897 respectively) is a possible risk of idiopathic oligospermia for men in Sichuan, China.

  2. The c.1,066A>T variant in the UBR2 gene is associated with increased susceptibility to azoospermia caused by meiotic arrest.

  3. Study provides functional data for the mouse ubiquitin protein ligase E3 component n-recognin 2 protein.

Mouse (Murine) Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) interaction partners

  1. Taken together, our findings indicated that p53(-/-) mBMMSC exosomes could deliver UBR2 to target cells and promote gastric cancer growth and metastasis by regulating Wnt/beta-catenin pathway.

  2. These data suggest that Tex19.1 and Ubr2 are required for mouse spermatocytes to accumulate sufficient Spo11-dependent recombination to ensure that the homology search is consistently successful, and reveal a hitherto unknown genetic pathway promoting meiotic recombination in mammals.

  3. Results suggest that UBR2 up-regulation in cachectic muscle is mediated by the p38beta-C/EBPbeta signaling pathway responsible for the bulk of tumor-induced muscle proteolysis.

  4. Results suggest that the binding of Ubr2 to Tex19.1 metabolically stabilizes Tex19.1 during spermatogenesis, revealing a new function for Ubr2 outside the conventional N-end rule pathway.

  5. insufficiency in UBR2-dependent histone ubiquitination triggers a pachytene checkpoint system, providing a new insight into chromatin remodeling and gene expression regulation

  6. UBR2 ubiquitin ligase and the N-end rule pathway are required for male meiosis and spermatogenesis and for an essential aspect of female embryonic development.

  7. mouse fibroblast cells derived from Ubr2 deficient embryos display genome instability.

  8. UBR1-/-UBR2-/- embryos die at midgestation, with defects in neurogenesis and cardiovascular development.

UBR2 profil antigène

Antigen Summary

This gene encodes an E3 ubiquitin ligase of the N-end rule proteolytic pathway that targets proteins with destabilizing N-terminal residues for polyubiquitylation and proteasome-mediated degradation. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with UBR2

  • ubiquitin protein ligase E3 component n-recognin 2 (UBR2) anticorps
  • ubiquitin protein ligase E3 component n-recognin 2 (ubr2) anticorps
  • ubiquitin protein ligase E3 component n-recognin 2 S homeolog (ubr2.S) anticorps
  • ubiquitin protein ligase E3 component n-recognin 2 (Ubr2) anticorps
  • 9930021A08Rik anticorps
  • AI462103 anticorps
  • AW540746 anticorps
  • bA49A4.1 anticorps
  • C6orf133 anticorps
  • dJ242G1.1 anticorps
  • dJ392M17.3 anticorps
  • E130209G04Rik anticorps
  • mKIAA0349 anticorps
  • RP3-392M17.3 anticorps
  • si:ch211-239i4.2 anticorps

Protein level used designations for UBR2

ubiquitin protein ligase E3 component n-recognin 2 , rp3-392m17.3 , E3 ubiquitin-protein ligase UBR2 , ubiquitin-protein ligase E3-alpha-2 , ubiquitin-protein ligase E3-alpha-II , N-recognin-2 , ubiquitin ligase E3 alpha-II

GENE ID SPECIES
100522688 Sus scrofa
100009912 Monodelphis domestica
100170193 Xenopus (Silurana) tropicalis
100542516 Meleagris gallopavo
559136 Danio rerio
734725 Xenopus laevis
421387 Gallus gallus
23304 Homo sapiens
474903 Canis lupus familiaris
527153 Bos taurus
224826 Mus musculus
363188 Rattus norvegicus
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