anti-Ubiquitin Specific Peptidase 9, X-Linked (USP9X) Anticorps

USP9X is a member of the peptidase C19 family and encodes a protein that is similar to ubiquitin-specific proteases. De plus, nous expédions et USP9X Protéines (1) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
USP9X 8239 Q93008
USP9X 363445  
USP9X 22284 P70398
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Top anti-USP9X Anticorps sur anticorps-enligne.fr

Showing 10 out of 82 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB Sample Type: 1. total HeLa cell extract (100ug)2.  total HeLa cell extract incubated with HA-UbVME (100ug)3. Rat Liver cytosolic extract (100ug)4. Rat Liver cytosolic extract incubated with HA-UbVME (100ug)Primary Dilution: 1:1000Secondary Antibody: alkaline phosphatase-conjugated anti-rabbitSecondary Dilution: 1:1000Image Submitted by: Andreia CarvalhoIBMC-OBF, Portugal . 100 μL Connectez-vous pour afficher 2 to 3 Days
$319.00
Détails
Chien Souris Inconjugué IHC, IHC (p), WB 100 μL Connectez-vous pour afficher 11 to 14 Days
$522.50
Détails
Humain Souris Inconjugué IF, ELISA, WB Immunofluorescence of monoclonal antibody to USP9X on HeLa cell. [antibody concentration 10 ug/ml] Detection limit for recombinant GST tagged USP9X is approximately 0.1ng/ml as a capture antibody. 100 μg Connectez-vous pour afficher 11 to 12 Days
$440.00
Détails
Humain Souris Inconjugué ELISA, IF, WB Immunofluorescence of monoclonal antibody to USP9X on HeLa cell (antibody concentration 10 µg/mL). USP9X monoclonal antibody (M01), clone 1C4 Western Blot analysis of USP9X expression in Hela NE. 100 μg Connectez-vous pour afficher 8 to 11 Days
$527.50
Détails
Humain Chèvre Inconjugué IHC, IHC (p) Brain, cortex, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-USP9X antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml. 50 μg Connectez-vous pour afficher 11 to 14 Days
$484.00
Détails
Humain Lapin Inconjugué IP, WB 0.1 mL Connectez-vous pour afficher 7 to 9 Days
$559.35
Détails
Humain Souris Inconjugué WB 100 μL Connectez-vous pour afficher 11 to 14 Days
$507.83
Détails
Roussette (Chauve-souris) Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 11 to 14 Days
$551.83
Détails
Humain Chèvre Inconjugué IHC (p) Immunohistochemistry-Paraffin: USP9x Antibody  - Analysis of anti-USP9X antibody with human brain, cortex at concentration 3.75 ug/ml. 0.05 mg Connectez-vous pour afficher 10 to 13 Days
$559.35
Détails
Humain Lapin Inconjugué IHC, WB Western blot analysis of USP9X in lysates of HeLa ABIN6273342 at 1/100 staining Human thyroid cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. 100 μL Connectez-vous pour afficher 11 to 12 Days
$390.77
Détails

anti-USP9X Anticorps mieux référencés

  1. Human Monoclonal USP9X Primary Antibody pour IF, ELISA - ABIN563570 : Mazumder, Choudhary, Al-Harbi, Almasan: Mcl-1 Phosphorylation defines ABT-737 resistance that can be overcome by increased NOXA expression in leukemic B cells. dans Cancer research 2012 (PubMed)
    Show all 6 Pubmed References

  2. Human Polyclonal USP9X Primary Antibody pour IP, WB - ABIN253244 : Pérez-Mancera, Rust, van der Weyden, Kristiansen, Li, Sarver, Silverstein, Grützmann, Aust, Rümmele, Knösel, Herd, Stemple, Kettleborough, Brosnan, Li, Morgan, Knight, Yu, Stegeman, Collier et al.: The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma. ... dans Nature 2012 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal USP9X Primary Antibody pour ICC, IF - ABIN4364640 : Tian, Alvarez-Saavedra, Cheng, Figeys: Uncovering the proteome response of the master circadian clock to light using an AutoProteome system. dans Molecular & cellular proteomics : MCP 2011 (PubMed)
    Show all 2 Pubmed References

  4. Human Monoclonal USP9X Primary Antibody pour ELISA, IF - ABIN393478 : Gingras, Gawor, Bernadzki, Grady, Hallock, Glass, Sanes, Proszynski: Α-Dystrobrevin-1 recruits Grb2 and α-catulin to organize neurotransmitter receptors at the neuromuscular junction. dans Journal of cell science 2016 (PubMed)

  5. Dog (Canine) Monoclonal USP9X Primary Antibody pour IHC, IHC (p) - ABIN4364645 : Peng, Hu, Liu, He, Cui, Chen, Yang, Liu, Wei, Liu, Wang: USP9X expression correlates with tumor progression and poor prognosis in esophageal squamous cell carcinoma. dans Diagnostic pathology 2014 (PubMed)

Plus d’anticorps contre USP9X partenaires d’interaction

Human Ubiquitin Specific Peptidase 9, X-Linked (USP9X) interaction partners

  1. Increased USP9X expression correlates with increased YAP1 protein in human breast cancer cell lines and patient samples. Moreover, depletion of USP9X increases YAP1 polyubiquitination, which in turn elevates YAP1 turnover and cell sensitivity to chemotherapy.

  2. Usp9x modulates and potentially coordinates multiple fate determinants in neural progenitors.

  3. USP9X is overexpressed in breast carcinomas, and its level of expression is correlated with that of CEP131. USP9X is an important regulator of centrosome biogenesis and USP9X/CEP131 plays a critical role in breast carcinogenesis.

  4. High USP9X expression is associated with Pancreatic Ductal Adenocarcinoma.

  5. USP9X is a deubiquitylase of the Hippo pathway kinase LATS2 and that the Hippo pathway functions as a downstream signaling cascade that mediates USP9X's tumor-suppressive activity.

  6. Ets-1 is induced by BRAF or MEK kinase inhibition, resulting in increased NRAS expression, which could be blocked by inactivation of Usp9x.

  7. LNC473 could recruit deubiquitinase USP9X to inhibit the ubiquitination level of survivin and then increase survivin expression.

  8. Study shows that USP9X deubiquitylating enzyme maintains RAPTOR protein levels, mTORC1 signalling and proliferation in neural progenitors. USP9X is the first deubiquitylating enzyme shown to stabilize RAPTOR.

  9. Deubiquitylating enzyme USP9X was overexpressed in gastric cancer, suggesting a potential implication as an oncogene, and was significantly associated with a poorer survival.

  10. Study demonstrated that USP9X acts as a tumor metastasis supporter in pancreatic ductal adenocarcinoma (PDAC), and its downregulation inhibited the migration and invasion of PDAC cells, while high expression of USP9X inhibited the apoptosis of cancer cells. Therefore, USP9X functioned as an oncogene in PDAC cells and is closely related with the expression of Snail, Twist and survivin.

  11. knockdown of USP9X was shown to confer resistance to apoptosis following pediatric T-cell acute lymphoblastic leukemia relevant chemotherapy drug treatment in Jurkat leukemia cells

  12. USP9X stabilizes beta-catenin and activates Wnt/beta-catenin signal pathway to promote glioma cell proliferation and survival.

  13. these findings demonstrate that USP9X is a novel regulator of Von Hippel-Lindau protein stability, and USP9X may be a therapeutic target for treatment of Von Hippel-Lindau protein-related tumors

  14. Loss of USP9X expression is associated with pancreatic cancer.

  15. Frame shift mutation in USP9X and deletion of the 5'UTR of the USP9X identified in two females with intellectual disability syndrome.

  16. High USP9X expression is associated with basal-like breast cancer.

  17. The authors find that primary human aggressive B-cell lymphoma samples exhibit high USP9X expression that correlate with XIAP overexpression.

  18. USP9x-SMAD4 Interaction is associated with Breast Cancer Metastasis.

  19. Data suggest that USP9X as an integral component of centrosome where it functions to stabilize PCM1 and CEP55 and to promote centrosome biogenesis; N-terminal domain of USP9X appears to be responsible for physical association of USP9X with PCM1 and CEP55. (USP9X = ubiquitin-specific protease 9X; PCM1 = pericentriolar material 1 protein; CEP55 = 55kDa centrosomal protein)

  20. USP9X recruited to the centrosome by NPHP5 protects NPHP5 from ubiquitination, thus favouring cilia assembly.

Mouse (Murine) Ubiquitin Specific Peptidase 9, X-Linked (USP9X) interaction partners

  1. Study shows that USP9X deubiquitylating enzyme maintains RAPTOR protein levels, mTORC1 signalling and proliferation in neural progenitors. USP9X is the first deubiquitylating enzyme shown to stabilize RAPTOR.

  2. Report crucial role of the spermatogonial USP9X during transition from the mitotic to meiotic phases and/or maintenance of early meiotic phase in spermatogenesis.

  3. these findings highlight the critical role played by USP9X in the normal morphological development of the postnatal dentate gyrus.

  4. these data suggest that TCR-mediated signals enhance Themis stability upon T cell development and identify USP9X as a key regulator of Themis protein turnover

  5. In B lymphocytes, Usp9X is required for the induction of PKCbeta kinase activity after B-Cell Antigen Receptor-dependent activation.

  6. Usp9X is a positive regulator of proximal TCR signaling in peripheral T cells and also contributes to T cell tolerance established during intrathymic development.

  7. we identified USP9X as a potential therapeutic target in prostate cancer cells and established WP1130 as a lead compound for the development of ERG-depleting drugs.

  8. Loss of Usp9x disrupts cortical architecture, hippocampal development and TGFbeta-mediated axonogenesis.

  9. USP9X is a crucial positive regulator of the T Cell Receptor signaling pathway and is required for T-cell function through the modulation of Carma1-Bcl10-Malt1 complex formation.

  10. the deubiquitinase USP9X as a novel mTORC1 and -2 binding partner that negatively regulates mTOR activity and skeletal muscle differentiation.

  11. loss of Usp9x enhances transformation and protects pancreatic cancer cells from anoikis

  12. Zymophagy, a novel selective autophagy pathway mediated by VMP1-USP9x-p62, prevents pancreatic cell death.

  13. Expressed in both germ cell and supporting cell lineages during mouse gonadal development in stage- and sex-dependent manners.

  14. Usp9x is significantly higher in the adult female mouse brains than in male brains. This implies that the difference in sex chromosome complement between XY males and XX females could potentially contribute to sexual differentiation of brain structure.

  15. Age-associated changes in DNA methylation and ubiquitin system protein concentrations potentially contribute to developmental changes in brain structure and function.

  16. USP9X-induced polarization of neural progenitors results in their radial arrangement, which provides an environment conducive for self-renewal.

USP9X profil antigène

Profil protéine

This gene is a member of the peptidase C19 family and encodes a protein that is similar to ubiquitin-specific proteases. Though this gene is located on the X chromosome, it escapes X-inactivation. Mutations in this gene have been associated with Turner syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene names and symbols associated with USP9X

  • ubiquitin specific peptidase 9, X-linked (USP9X) anticorps
  • ubiquitin specific peptidase 9, X-linked (Usp9x) anticorps
  • ubiquitin specific peptidase 9, X-linked (usp9x) anticorps
  • ubiquitin specific peptidase 9, X chromosome (Usp9x) anticorps
  • 5730589N07Rik anticorps
  • AA407302 anticorps
  • AA407699 anticorps
  • AL022658 anticorps
  • AL022749 anticorps
  • Dffrx anticorps
  • faf anticorps
  • FAF-X anticorps
  • Fafl anticorps
  • fam anticorps
  • RGD1560056 anticorps

Protein level used designations for USP9X

Drosophila fat facets related, X-linked , deubiquitinating enzyme FAF-X , fat facets in mammals , fat facets protein related, X-linked , fat facets protein-related, X-linked , hFAM , probable ubiquitin carboxyl-terminal hydrolase FAF-X , ubiquitin specific protease 9, X chromosome (fat facets-like Drosophila) , ubiquitin thioesterase FAF-X , ubiquitin thiolesterase FAF-X , ubiquitin-specific processing protease FAF-X , ubiquitin-specific protease 9, X chromosome , ubiquitin-specific-processing protease FAF-X , ubiquitin specific peptidase 9, X chromosome , ubiquitin specific peptidase 9, X-linked , ubiquitin specific protease 9, X-linked , probable ubiquitin carboxyl-terminal hydrolase FAF-X-like , fat facets homolog , fats facets protein related, X , ubiquitin carboxyl-terminal hydrolase FAM , ubiquitin specific protease 9 SSSRF- isoform , ubiquitin specific protease 9, X chromosome

GENE ID SPECIES
8239 Homo sapiens
363445 Rattus norvegicus
418569 Gallus gallus
507307 Bos taurus
700135 Macaca mulatta
100050489 Equus caballus
100156786 Sus scrofa
100170466 Xenopus (Silurana) tropicalis
100398696 Callithrix jacchus
100446206 Pongo abelii
100464801 Ailuropoda melanoleuca
100544793 Meleagris gallopavo
100565169 Anolis carolinensis
100587865 Nomascus leucogenys
22284 Mus musculus
480885 Canis lupus familiaris
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