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The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. De plus, nous expédions Ubiquitin-Conjugating Enzyme E2L 6 Protéines (15) et beaucoup plus de produits pour cette protéine.
Showing 10 out of 69 products:
Human Polyclonal UBE2L6 Primary Antibody pour IHC (p), WB - ABIN1882146
Kumar, Kao, Howley: Physical interaction between specific E2 and Hect E3 enzymes determines functional cooperativity. dans The Journal of biological chemistry 1997
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Human Polyclonal UBE2L6 Primary Antibody pour IHC (p), WB - ABIN388854
Krämer, Müller, Buchwald, Reichardt, Heinzel: Mechanism for ubiquitylation of the leukemia fusion proteins AML1-ETO and PML-RARalpha. dans FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008
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Human Monoclonal UBE2L6 Primary Antibody pour ELISA, WB - ABIN563994
Zhang, Adyshev, Singleton, Li, Cepeda, Huang, Zou, Verin, Tu, Garcia, Ye: Interactions between PBEF and oxidative stress proteins--a potential new mechanism underlying PBEF in the pathogenesis of acute lung injury. dans FEBS letters 2008
Cow (Bovine) Polyclonal UBE2L6 Primary Antibody pour WB - ABIN2775688
Li, Wang, Yang, Li, Qin, Dong, Zhu, Liang, Liang, Han: The Spen homolog Msx2-interacting nuclear target protein interacts with the E2 ubiquitin-conjugating enzyme UbcH8. dans Molecular and cellular biochemistry 2006
Depletion of either ISG15 (Montrer ISG15 Anticorps) or UBE2L6/UBCH8 resulted in enhanced endogenous autophagic flux.
Data indicate that reduced expression of the ubiquitin-conjugating enzyme (Montrer Ube2t Anticorps) UbcH8 (Montrer UBE2E2 Anticorps) protein correlated with poor outcome in nasopharyngeal carcinoma (NPC (Montrer NPC1 Anticorps)) patients.
study reports that UBCH8 (Montrer UBE2E2 Anticorps) and UBE2G1 (Montrer Ube2g1 Anticorps) and UBE2G2 (Montrer UBE2G2 Anticorps) cooperate with CRL4Cdt2 in promoting the polyubiquitylation and subsequent degradation of p21 (Montrer CDKN1A Anticorps) and Cdt1 (Montrer CDT1 Anticorps), respectively
gain and loss-of-function approaches show that UBCH8 (Montrer UBE2E2 Anticorps) and the ubiquitin-ligase SIAH1 physically interact with and target FLT3 (Montrer FLT3 Anticorps)-ITD for proteasomal degradation
The structure of UbcH8 does not undergo a significant conformational change upon forming a complex with ubiquitin.
Quantitative-PCR and Northern analysis confirmed down-regulation of UCRP and UBE2L6 with BRCA2 (Montrer BRCA2 Anticorps) knockdown, respectively.
Ube1L (Montrer UBA7 Anticorps) was required for transfer of ISG15 (Montrer ISG15 Anticorps) to UbcH8 (Montrer UBE2E2 Anticorps) and for binding of Ube1L (Montrer UBA7 Anticorps) to UbcH8 (Montrer UBE2E2 Anticorps)
we have identified a loss-of-function mutation in Ube2l6 that contributes to the chromosome 2 obesity quantitative trait locus (Montrer MC3R Anticorps).
Ubc8 (Montrer UBE2H Anticorps) is a major ISG15 (Montrer ISG15 Anticorps)-conjugating enzyme responsible for protein ISGylation upon interferon (Montrer IFNA Anticorps) stimulation
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by the UBE2L3 gene. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
ubiquitin-conjugating enzyme E2L 6
, ubiquitin/ISG15-conjugating enzyme E2 L6
, retinoic acid induced gene B protein
, retinoic acid-induced gene B protein
, ubiquitin carrier protein L6
, ubiquitin-protein ligase L6
, E2 ubiquitin conjugating enzyme
, ubiquitin-conjugating enzyme 8
, Ubiquitin carrier protein L6
, Ubiquitin-protein ligase L6