anti-Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6) Anticorps

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. De plus, nous expédions Ubiquitin-Conjugating Enzyme E2L 6 Protéines (15) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
UBE2L6 9246 O14933
UBE2L6 56791 Q9QZU9
UBE2L6 295704 Q4V8J2
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Top anti-Ubiquitin-Conjugating Enzyme E2L 6 Anticorps sur anticorps-enligne.fr

Showing 10 out of 69 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB <b>WB Suggested Anti-UBE2L6 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>MCF7 cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-UBE2L6 Antibody  Positive Control: Lane1: 70ug U6A lysate, Lane, 2: 70ug IFN-g stimulated U6A lysate  Primary Antibody Dilution :  1:2000 Secondary Antibody :  Anti-rabbit-HRP  Secondry Antibody Dilution :  1:5000 Submitted by: Torsten Ginter & Dr. Oliver Kramer, Institute for Biochemistry and Biophysicws, Center for Biomedicine, Friedrich-Schiller University WB Suggested Anti-UBE2L6 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Human Small Intestine 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué IHC (p), WB The UBE2L6 Antibody (C-term) (ABIN388854) is used in Western blot to detect UBE2L6 in HL-60 cell lysate. Formalin-fixed and paraffin-embedded breast carcinoma tissue reacted with UBE2L6 Antibody (C-term)(ABIN388854), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Connectez-vous pour afficher 10 to 11 Days
$324.50
Détails
Humain Souris Inconjugué EIA, IHC (p), WB 0.1 mL Connectez-vous pour afficher 6 to 8 Days
$412.50
Détails
Humain Lapin Inconjugué IHC (p), WB Western blot analysis of hUBE2L6-M1 (ABIN1882146) in HL60 cell line lysates (35 µg/lane). UBE2L6 (arrow) was detected using the purified Pab. Western blot analysis of hUBE2L6-M1 (ABIN1882146) in HL60 cell line lysates (35 µg/lane). UBE2L6 (arrow) was detected using the purified Pab. 400 μL Connectez-vous pour afficher 10 to 11 Days
$324.50
Détails
Humain Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Humain Lapin Inconjugué EIA, IHC (p), WB   0.4 mL Connectez-vous pour afficher 12 to 15 Days
$375.38
Détails
Humain Souris Inconjugué IHC (p), IHC, ELISA, WB Immunohistochemistry-Paraffin: UbcH8/Ube2L6 Antibody (k1H3) [NBP1-04351] - Ube2L6 Antibody (k1H3) [NBP1-04351]-Paraffin embedded sections of human breast lobule tissue were incubated with anti-human UBE2L6 for 2 hours at room temperature. Antigen retrieval was performed in 0.1M sodium citrate buffer and detected using Diaminobenzidine (DAB) Western Blot: UbcH8/Ube2L6 Antibody (k1H3) [NBP1-04351] - Ube2L6 Antibody (k1H3) [NBP1-04351]-Cell lysates of MCF7 (20ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with anti-human UBE2L6 . Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. 0.1 mL Connectez-vous pour afficher 7 to 9 Days
$381.94
Détails
Humain Souris Inconjugué ELISA, WB Western Blot analysis of UBE2L6 expression in transfected 293T cell line by UBE2L6 monoclonal antibody (M01), clone 2F12-1F4.<br><br>Lane 1: UBE2L6 transfected lysate(17.595 KDa).<br>Lane 2: Non-transfected lysate.<br> Detection limit for recombinant GST tagged UBE2L6 is 3 ng/ml as a capture antibody. 100 μg Connectez-vous pour afficher 11 to 12 Days
$430.00
Détails
Humain Souris Inconjugué IHC (p), ELISA, WB Human Spleen (formalin-fixed, paraffin-embedded) stained with UBE2L6 antibody ABIN364358 at 5 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. Human Thymus (formalin-fixed, paraffin-embedded) stained with UBE2L6 antibody ABIN364358 at 5 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. 50 μg Connectez-vous pour afficher 7 to 9 Days
$451.00
Détails

UBE2L6 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
Human ,
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Mouse (Murine)


Rat (Rattus)


anti-Ubiquitin-Conjugating Enzyme E2L 6 Anticorps mieux référencés

  1. Human Polyclonal UBE2L6 Primary Antibody pour IHC (p), WB - ABIN1882146 : Kumar, Kao, Howley: Physical interaction between specific E2 and Hect E3 enzymes determines functional cooperativity. dans The Journal of biological chemistry 1997 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal UBE2L6 Primary Antibody pour IHC (p), WB - ABIN388854 : Krämer, Müller, Buchwald, Reichardt, Heinzel: Mechanism for ubiquitylation of the leukemia fusion proteins AML1-ETO and PML-RARalpha. dans FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008 (PubMed)
    Show all 3 Pubmed References

  3. Human Monoclonal UBE2L6 Primary Antibody pour ELISA, WB - ABIN563994 : Zhang, Adyshev, Singleton, Li, Cepeda, Huang, Zou, Verin, Tu, Garcia, Ye: Interactions between PBEF and oxidative stress proteins--a potential new mechanism underlying PBEF in the pathogenesis of acute lung injury. dans FEBS letters 2008 (PubMed)

  4. Cow (Bovine) Polyclonal UBE2L6 Primary Antibody pour WB - ABIN2775687 : Li, Wang, Yang, Li, Qin, Dong, Zhu, Liang, Liang, Han: The Spen homolog Msx2-interacting nuclear target protein interacts with the E2 ubiquitin-conjugating enzyme UbcH8. dans Molecular and cellular biochemistry 2006 (PubMed)

Plus d’anticorps contre Ubiquitin-Conjugating Enzyme E2L 6 partenaires d’interaction

Human Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6) interaction partners

  1. Depletion of either ISG15 (Montrer ISG15 Anticorps) or UBE2L6/UBCH8 resulted in enhanced endogenous autophagic flux.

  2. Data indicate that reduced expression of the ubiquitin-conjugating enzyme (Montrer Ube2t Anticorps) UbcH8 (Montrer UBE2E2 Anticorps) protein correlated with poor outcome in nasopharyngeal carcinoma (NPC (Montrer NPC1 Anticorps)) patients.

  3. study reports that UBCH8 (Montrer UBE2E2 Anticorps) and UBE2G1 (Montrer Ube2g1 Anticorps) and UBE2G2 (Montrer UBE2G2 Anticorps) cooperate with CRL4Cdt2 in promoting the polyubiquitylation and subsequent degradation of p21 (Montrer CDKN1A Anticorps) and Cdt1 (Montrer CDT1 Anticorps), respectively

  4. gain and loss-of-function approaches show that UBCH8 (Montrer UBE2E2 Anticorps) and the ubiquitin-ligase SIAH1 physically interact with and target FLT3 (Montrer FLT3 Anticorps)-ITD for proteasomal degradation

  5. The structure of UbcH8 does not undergo a significant conformational change upon forming a complex with ubiquitin.

  6. Quantitative-PCR and Northern analysis confirmed down-regulation of UCRP and UBE2L6 with BRCA2 (Montrer BRCA2 Anticorps) knockdown, respectively.

  7. Ube1L (Montrer UBA7 Anticorps) was required for transfer of ISG15 (Montrer ISG15 Anticorps) to UbcH8 (Montrer UBE2E2 Anticorps) and for binding of Ube1L (Montrer UBA7 Anticorps) to UbcH8 (Montrer UBE2E2 Anticorps)

Mouse (Murine) Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6) interaction partners

  1. we have identified a loss-of-function mutation in Ube2l6 that contributes to the chromosome 2 obesity quantitative trait locus (Montrer MC3R Anticorps).

  2. Ubc8 (Montrer UBE2H Anticorps) is a major ISG15 (Montrer ISG15 Anticorps)-conjugating enzyme responsible for protein ISGylation upon interferon (Montrer IFNA Anticorps) stimulation

Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6) profil antigène

Profil protéine

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by the UBE2L3 gene. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene names and symbols associated with UBE2L6

  • ubiquitin conjugating enzyme E2 L6 (UBE2L6) anticorps
  • ubiquitin-conjugating enzyme E2L 6 (Ube2l6) anticorps
  • 2810489I21Rik anticorps
  • RIG-B anticorps
  • Ubce8 anticorps
  • UBCH8 anticorps
  • UbcM8 anticorps
  • UBE2L6 anticorps

Protein level used designations for UBE2L6

ubiquitin-conjugating enzyme E2L 6 , ubiquitin/ISG15-conjugating enzyme E2 L6 , retinoic acid induced gene B protein , retinoic acid-induced gene B protein , ubiquitin carrier protein L6 , ubiquitin-protein ligase L6 , E2 ubiquitin conjugating enzyme , ubiquitin-conjugating enzyme 8 , ubcM8 , Ubiquitin carrier protein L6 , Ubiquitin-protein ligase L6

GENE ID SPECIES
466588 Pan troglodytes
475967 Canis lupus familiaris
100349814 Oryctolagus cuniculus
100514753 Sus scrofa
9246 Homo sapiens
56791 Mus musculus
295704 Rattus norvegicus
509471 Bos taurus
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