anti-Vestigial Like 4 (Drosophila) (VGLL4) Anticorps

May act as a specific coactivator for the mammalian TEFs (By similarity).. De plus, nous expédions Vestigial Like 4 (Drosophila) Protéines (5) et et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
VGLL4 297523  
VGLL4 9686 Q14135
VGLL4 232334 Q80V24
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Top anti-Vestigial Like 4 (Drosophila) Anticorps sur

Showing 10 out of 49 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB Host: Rabbit Target Name: VGLL4 Sample Type: OVCAR-3 Whole Cell lysates Antibody Dilution: 1.0ug/ml 100 μL 2 to 3 Days
Boeuf (Vache) Lapin Inconjugué WB Host: Rabbit Target Name: VGLL4 Sample Tissue: Human HT1080 Whole Cell Antibody Dilution: 1ug/ml 100 μL 2 to 3 Days
Humain Lapin Inconjugué WB Western Blot at 1:1000 dilution + human uterus lysate Lysates/proteins at 20 ug per lane. 400 μL 2 to 3 Days
Souris Lapin Inconjugué WB Western blot analysis of extracts of mouse thymus, using VGLL4 antibody. 200 μL 12 to 14 Days
Humain Souris Inconjugué WB Western Blot analysis of VGLL4 expression in transfected 293T cell line by VGLL4 MaxPab polyclonal antibody.Lane 1: VGLL4 transfected lysate(31.9 KDa).Lane 2: Non-transfected lysate. VGLL4 MaxPab polyclonal antibody. Western Blot analysis of VGLL4 expression in Hela S3 NE. 50 μg 11 to 12 Days
Humain Lapin Inconjugué WB   100 μL 11 to 14 Days
Humain Lapin Inconjugué ELISA, WB   200 μL 11 to 16 Days
Humain Lapin Cy7 IF (p)   100 μL 14 to 21 Days
Humain Lapin Cy5 IF (p)   100 μL 14 to 21 Days
Humain Lapin Cy5.5 IF (p)   100 μL 14 to 21 Days

anti-Vestigial Like 4 (Drosophila) Anticorps mieux référencés

  1. Human Polyclonal VGLL4 Primary Antibody pour ICC, IF - ABIN4365266 : Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. dans Nature methods 2013 (PubMed)

Plus d’anticorps contre Vestigial Like 4 (Drosophila) partenaires d’interaction

Human Vestigial Like 4 (Drosophila) (VGLL4) interaction partners

  1. our RNA-seq analyses suggest that while the stimulatory effects of CytoD on osteogenesis are pleiotropic and depend on the biological state of the cell type, a small group of genes including VGLL4 may contribute to MSC commitment toward the bone lineage.

  2. Data report that VGLL4 functions as a suppressor of breast tumor (BC) growth and progression. Its low expression correlated with a poor prognosis. Its ectopic expression in BC cell lines reduced cell proliferation, migration, and tumor formation in xenograft mouse model. VGLL4 interacts with TEAD1 via its second TEAD-interacting domain, antagonizing YAP-dependent tumor growth.

  3. Hippo pathway transcription factor TEAD4 directly associates with the Wnt pathway transcription factor TCF4 via their DNA-binding domains, forming a complex on target genes. VGLL4 binds to this TEAD4-TCF4 complex to inhibit transactivation of both TCF4 and TEAD4.

  4. Results identify VGLL4 as a direct target gene of miR-130b in Bladder cancer (BCa) cells. Its suppression is crucial for miR-130b-induced BCa cell proliferation, migration and invasion.

  5. The Vgll4 is phosphorylated in vitro and in vivo by cyclin-dependent kinase 1 (CDK1) during antimitotic drug-induced mitotic arrest and also in normal mitosis.

  6. VGLL4 - novel candidate genes validated in a large case-control sample of schizophrenia.

  7. The expression level of VGLL4 protein was down-regulated in gastric cancer tissues.VGLL4 inhibits epithelial-mesenchymal transition in part through suppressing Wnt-beta-catenin signaling pathway in gastric cancer.

  8. our study suggested that downregulation of VGLL4 was very important in the progression of ESCC, and restoring the function of VGLL4 might be a promising therapeutic strategy for ESCC.

  9. VGLL4 directly competes with YAP in binding to TEADs and executes its growth-inhibitory function through two TDU domains.

  10. rs2616551 in VGLL4 was found to be nominally associated with anorexia nervosa.

  11. This study introduces a novel gain-of-function approach for studying hESC maintenance and presents VGLL4 as a previously undescribed regulator of this process.

  12. Loss of VGLL4 expression is associated with gastric cancer.

  13. Vgl-4 may play a role in the apoptotic pathways by regulating translocation of IAPs between different cell compartments.

  14. IRF2BP2 was identifies as a novel VGLL4 partner.

  15. This gene is named Vestigial-like 4, to distinguish it from 3 previously described genes Vgl-1, Vgl-2 and Vgl-3. Contains 2 motifs, found in the Drosophila transcription cofactor Vestigial, that interact with the TEF-1 family of transcription factors.

Mouse (Murine) Vestigial Like 4 (Drosophila) (VGLL4) interaction partners

  1. VGLL4 acted as an adaptor protein that enhanced the interaction between TEAD4 and CtBP2, and this TEAD4-VGLL4-CtBP2 ternary complex dynamically existed at the early stage of adipogenesis.

  2. Results revealed an essential role of VGLL4 in heart valve morphogenesis via regulating valvar interstitial cells proliferation and apoptosis. Furthermore, its deletion resulted in progressive valve disease. These findings suggest that mutations in VGLL4 may underlie human congenital heart valve dysplasia.

  3. Adenovirus armed with VGLL4 selectively kills hepatocellular carcinoma in a mouse model with G2/M phase arrest and apoptosis promotion.

  4. VGLL4 inhibits cardiomyocyte proliferation by inhibiting TEAD1-YAP interaction and by targeting TEAD1 for degradation.

  5. Vgl-4 modulates the activity of TEF-1 factors and counteracts alpha1-adrenergic activation of gene expression in cardiac myocytes

Vestigial Like 4 (Drosophila) (VGLL4) profil antigène

Profil protéine

May act as a specific coactivator for the mammalian TEFs (By similarity).

Gene names and symbols associated with VGLL4

  • vestigial-like family member 4 (Vgll4) anticorps
  • vestigial like family member 4 (VGLL4) anticorps
  • vestigial like family member 4 (Vgll4) anticorps
  • BC048841 anticorps
  • DKFZp459C0333 anticorps
  • VGL-4 anticorps

Protein level used designations for VGLL4

transcription cofactor vestigial-like protein 4 , Vestigial-like 4

297523 Rattus norvegicus
415962 Gallus gallus
607588 Canis lupus familiaris
613904 Bos taurus
100171928 Pongo abelii
9686 Homo sapiens
232334 Mus musculus
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