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WFDC2 encodes a protein that is a member of the WFDC domain family. De plus, nous expédions WFDC2 Anticorps (175) et WFDC2 Protéines (27) et beaucoup plus de produits pour cette protéine.
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Serum HE4 with its high specificity is useful in ruling out ovarian malignancy especially among the premenopausal women and Risk of Ovarian Malignancy Algorithm (ROMA)which is the combination of both serum CA 125 (Montrer MUC16 Kits ELISA) and HE4, appears to be an all-rounder with overall good sensitivity and specificity especially among the postmenopausal women.
CA125 (Montrer MUC16 Kits ELISA) appears the most reliable biomarker for OC monitoring, whereas HE4 contributes additional information only in a minority of cases
level of HE4 might predict chemoresistance and the possibility of ascites formation. The determination of the expression of HE4 alone or combined with CA125 (Montrer MUC16 Kits ELISA) levels in both serum and ascites in ovarian cancer patients with ascites may have important significance for guiding and improving the treatment
Elevated serum HE4 in SLE patients is significantly associated with a higher risk of incidence for lupus nephritis (LN), and may be a useful predictor for developing LN.
HE4 has the potential to be used as a novel clinical biomarker for evaluating kidney function and predicting renal fibrosis in kidney transplant recipients
A panel of three tumor markers CYFRA 21.1, HE4 and ProGRP may play a role for discriminating LC from benign lung disease and subtyping as SCLC.
Serum Smac (Montrer DIABLO Kits ELISA) expression level was significantly lower in the EAOC group than in the control group and benign ovarian tumor group (P< 0.05), while HE4 and CA125 (Montrer MUC16 Kits ELISA) expression levels were significantly higher in the EAOC group than the other two groups.
This study demonstrated that altered expression of HE4 may involve in tumorigenesis in the uterine cervix. Our findings also suggested the presence of a correlation between HE4 expression and the invasive potential of uterine tumors. Therefore it may be thought that the tissue expression of HE4 can be used to differentiate high grade intraepithelial tumors from carcinomas.
High serum HE4 level is associated with epithelial ovarian cancer.
Use of HE4 instead of CA125 (Montrer MUC16 Kits ELISA) did not significantly improve diagnostic performance of risk of malignancy indices 1-4 in patients with an adnexal mass
Causal testing implicates Wfdc2 and Hdac3 (Montrer HDAC3 Kits ELISA) as novel genes affecting high density lipoprotein levels
This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation.
WAP four-disulfide core domain 2
, WAP four-disulfide core domain 3
, WAP four-disulfide core domain protein 2
, WAP domain containing protein HE4-V4
, epididymal protein 4
, epididymal secretory protein E4
, epididymis-specific, whey-acidic protein type, four-disulfide core
, major epididymis-specific protein E4
, putative protease inhibitor WAP5
, WAP domain-containing protein HE4
, epididymal secretory protein 4
, epididymal protein BE-20