anti-WD Repeat Domain, Phosphoinositide Interacting 2 (WIPI2) Anticorps

WD40 repeat proteins are key components of many essential biologic functions. De plus, nous expédions WIPI2 Protéines (4) et et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
WIPI2 26100 Q9Y4P8
WIPI2 74781 Q80W47
WIPI2 288498 Q6AY57
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Top anti-WIPI2 Anticorps sur anticorps-enligne.fr

Showing 10 out of 120 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB Host: Rabbit  Target Name: WIPI2  Sample Tissue: Human Fetal Lung  Antibody Dilution: 1.0 µg/mL 100 μL 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué ELISA, WB 0.1 mg 2 to 3 Days
$360.00
Détails
Humain Lapin Inconjugué EIA, WB Western blot analysis of WIPI2 Antibody (C-term) in mouse brain tissue lysates (35 µg/lane). WIPI2 (arrow) was detected using the purified Pab. 0.4 mL 6 to 8 Days
$484.00
Détails
Humain Lapin Inconjugué IHC, WB Western blot analysis of extracts of Raji cells, using Phospho-WIPI2 (Ser413) Antibody. ABIN6267207 at 1/100 staining Human thyroid cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. 100 μL 11 to 12 Days
$390.77
Détails
Cobaye Souris Inconjugué IF, IHC, IHC (p), IP, WB Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg 11 to 14 Days
$484.00
Détails
Humain Lapin Inconjugué IHC, WB Western blot analysis of extracts of Human placenta tissue, using WIPI2 Antibody. ABIN6267216 at 1/100 staining Human thyroid cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. 100 μL 11 to 12 Days
$390.77
Détails
Humain Lapin Inconjugué ELISA, WB   100 μL Disponible
$363.46
Détails
Humain Lapin Inconjugué EIA, WB   0.1 mg 4 to 8 Days
$522.50
Détails
Humain Lapin FITC ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Rabbit Anti-WIPI2 Polyclonal Antibody . Tissue: HeLa Cells (Human Cervical Cancer). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Rabbit Anti-WIPI2 Polyclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Rabbit ATTO 488 at 1:200 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60 min at RT, 5 min at RT. Localization: Cytoplasm . Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) WIPI2 Antibody (D) Composite. Western blot analysis of Human HeLa and 293Trap cell lysates showing detection of ~49.4 kDa WIPI2 protein using Rabbit Anti-WIPI2 Polyclonal Antibody . Lane 1: Molecular Weight Ladder (MW). Lane 2: HeLa cell lysates. Lane 3: 293Trap cell lysates. Load: 15 µg. Block: 5% Skim Milk in 1X TBST. Primary Antibody: Rabbit Anti-WIPI2 Polyclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Goat Anti-Rabbit IgG: HRP at 1:1000 for 60 min at RT. Color Development: ECL solution for 6 min in RT. Predicted/Observed Size: ~49.4 kDa. 100 μg 3 to 4 Days
$505.70
Détails
Humain Lapin PerCP ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Rabbit Anti-WIPI2 Polyclonal Antibody . Tissue: HeLa Cells (Human Cervical Cancer). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Rabbit Anti-WIPI2 Polyclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Rabbit ATTO 488 at 1:200 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60 min at RT, 5 min at RT. Localization: Cytoplasm . Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) WIPI2 Antibody (D) Composite. Western blot analysis of Human HeLa and 293Trap cell lysates showing detection of ~49.4 kDa WIPI2 protein using Rabbit Anti-WIPI2 Polyclonal Antibody . Lane 1: Molecular Weight Ladder (MW). Lane 2: HeLa cell lysates. Lane 3: 293Trap cell lysates. Load: 15 µg. Block: 5% Skim Milk in 1X TBST. Primary Antibody: Rabbit Anti-WIPI2 Polyclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Goat Anti-Rabbit IgG: HRP at 1:1000 for 60 min at RT. Color Development: ECL solution for 6 min in RT. Predicted/Observed Size: ~49.4 kDa. 100 μg 3 to 4 Days
$514.80
Détails

anti-WIPI2 Anticorps mieux référencés

  1. Human Monoclonal WIPI2 Primary Antibody pour IF, IHC (p) - ABIN2477140 : Galligan, North: Drug receptors on single enteric neurons. dans Life sciences 1989 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal WIPI2 Primary Antibody pour ICC, IF - ABIN4366113 : Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. dans Nature methods 2013 (PubMed)

Plus d’anticorps contre WIPI2 partenaires d’interaction

Human WD Repeat Domain, Phosphoinositide Interacting 2 (WIPI2) interaction partners

  1. Regulation of the intracellular WIPI2 protein level by mTORC1 and HUWE1 is a key determinant of autophagy flux.

  2. Results suggest that Optn potentiates LC3-II production and maturation of the phagophore into the autophagosome, by facilitating the recruitment of the Atg12-5-16L1 complex to Wipi2-positive phagophores.

  3. Data suggest that, in patients with diabetic kidney disease, urinary excretion of mRNAs for MAP1LC3A, WIPI2, and RB1CC1 is down-regulated as compared to healthy control subjects; these transcripts may serve as urinary autophagy biomarkers. (MAP1LC3A = microtubule associated protein 1 light chain 3; WIPI2 = WD repeat domain phosphoinositide-interacting protein 2; RB1CC1 = RB1 inducible coiled-coil 1)

  4. Here the authors show that recruitment of WIPI2, itself essential for anti-bacterial autophagy, is dependent on the localization of catalytically active TBK1 to the vicinity of cytosolic bacteria.

  5. The specific autophagosomal localization of both WIPI1 and WIPI2 (refered to as WIPI puncta) has been employed to assess autophagy using fluorescence microscopy methods, such as confocal and live-cell video microscopy

  6. Data suggest WIPI1/WIPI2 co-localize with microtubule-associated light chain 3 and autophagy related proteins 2/14L, participate in biogenesis of phagosomes, autophagy, and mobilization of lipids to/from intracellular droplets. [review-like article]

  7. WIPI-1 and WIPI-2 are functionally required in mediating the PI3P signal at the onset of autophagy in NB4 cells.

  8. Data suggest that WIPI2b directly interacts with dimer of ATG16L1 (autophagy related 16-like 1) and this interaction is linked to production of phosphatidylinositol 3-phosphate in endoplasmic reticulum triggered by autophagosome formation. [REVIEW]

  9. WIPI2b binds the membrane surrounding Salmonella and recruits the Atg12-5-16L1 complex, initiating LC3 conjugation, autophagosomal membrane formation, and engulfment of Salmonella.

  10. WIPI2 is a phosphatidylinsitol-3-phosphate binding protein required for starvation induced autophagy.

  11. Freeze-fracture replica immunolabelling reveals WD-repeat protein interacting with phosphoinositides 1 and 2 (WIPI-1 and WIPI-2) as membrane components of autophagosomes and the plasma membrane (PM).

WIPI2 profil antigène

Profil protéine

WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI2, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al., 2004

Gene names and symbols associated with WIPI2

  • WD repeat domain, phosphoinositide interacting 2 L homeolog (wipi2.L) anticorps
  • WD repeat domain, phosphoinositide interacting 2 (WIPI2) anticorps
  • WD repeat domain, phosphoinositide interacting 2 (Wipi2) anticorps
  • 1110018O08Rik anticorps
  • 2510001I10Rik anticorps
  • ATG18B anticorps
  • Atg21 anticorps
  • WIPI-2 anticorps

Protein level used designations for WIPI2

WIPI-2 , WD repeat domain phosphoinositide-interacting protein 2 , WD40 repeat protein interacting with phosphoinositides 2 , WIPI49-like protein 2

GENE ID SPECIES
380011 Xenopus laevis
26100 Homo sapiens
74781 Mus musculus
288498 Rattus norvegicus
416481 Gallus gallus
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