anti-WD Repeat and FYVE Domain Containing 3 (WDFY3) Anticorps

WDFY3 encodes a phosphatidylinositol 3-phosphate-binding protein that functions as a master conductor for aggregate clearance by autophagy.

afficher tous les anticorps Gène GeneID UniProt
Anti-Humain WDFY3 WDFY3 23001 Q8IZQ1
Anti-Souris WDFY3 WDFY3 72145 Q6VNB8
Anti-Rat WDFY3 WDFY3 305164  
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Top anti-WDFY3 Anticorps sur anticorps-enligne.fr

Showing 10 out of 95 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-WDFY3 Antibody Titration:  0.2-1 ug/ml  Positive Control:  Human brain Host:  Rabbit  Target Name:  WDFY3  Sample Tissue:  Human Fetal Liver  Antibody Dilution:  1.0ug/ml 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-WDFY3 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:12500  Positive Control:  Human Muscle 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué EM, ICC, IF, IHC, IHC (p), IP, WB Immunohistochemistry-Paraffin: WDFY3 Antibody [NBP1-03332] - FFPE section of human ovarian carcinoma. Immunohistochemistry-Paraffin: WDFY3 Antibody [NBP1-03332] - FFPE section of human glioblastoma dilution of 1:5,000 (0.2ug/ml). Detection: DAB 100 μL Connectez-vous pour afficher 7 to 9 Days
$556.31
Détails
Cobaye Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Souris Chèvre Inconjugué ELISA, WB   100 μg Connectez-vous pour afficher 6 to 7 Days
$358.02
Détails
Humain Lapin Inconjugué ELISA, WB 50 μg Connectez-vous pour afficher 2 to 3 Days
$446.88
Détails
Humain Lapin Inconjugué IHC Immunohistochemistry-Paraffin: WDFY3 Antibody  - Staining of human duodenum shows strong granular cytoplasmic positivity in glandular cells. Immunocytochemistry/Immunofluorescence: WDFY3 Antibody  - Immunofluorescent staining of human cell line A549 shows localization to nucleoli & cytosol. 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$491.63
Détails
Humain Lapin HRP ICC, IF, WB Immunocytochemistry/Immunofluorescence analysis using Rabbit Anti-WDFY3 Polyclonal Antibody . Tissue: Colon carcinoma cell line (RKO). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Rabbit Anti-WDFY3 Polyclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Rabbit ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60 min at RT, 5 min at RT. Localization: Cytoplasm, Nucleus, Membrane. Magnification: 60X. (A) DAPI nuclear stain. (B) Phalloidin Texas Red F-Actin stain. (C) WDFY3 Antibody. (D) Composite. Western blot analysis of Human HeLa and 293Trap cell lysates showing detection of 395.2 kDa WDFY3 protein using Rabbit Anti-WDFY3 Polyclonal Antibody . Lane 1: Molecular Weight Ladder (MW). Lane 2: Human HeLa and 293Trap cell lysates. Load: 15 µg . Block: 5% Skim Milk in 1X TBST. Primary Antibody: Rabbit Anti-WDFY3 Polyclonal Antibody  at 1:1000 for 1 hour at RT. Secondary Antibody: Goat Anti-Rabbit HRP at 1:2000 for 60 min at RT. Color Development: ECL solution for 6 min in RT. Predicted/Observed Size: 395.2 kDa. 100 μg Connectez-vous pour afficher 2 to 3 Days
$487.03
Détails
Humain Lapin FITC ICC, IF, WB Immunocytochemistry/Immunofluorescence analysis using Rabbit Anti-WDFY3 Polyclonal Antibody . Tissue: Colon carcinoma cell line (RKO). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Rabbit Anti-WDFY3 Polyclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Rabbit ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60 min at RT, 5 min at RT. Localization: Cytoplasm, Nucleus, Membrane. Magnification: 60X. (A) DAPI nuclear stain. (B) Phalloidin Texas Red F-Actin stain. (C) WDFY3 Antibody. (D) Composite. Western blot analysis of Human HeLa and 293Trap cell lysates showing detection of 395.2 kDa WDFY3 protein using Rabbit Anti-WDFY3 Polyclonal Antibody . Lane 1: Molecular Weight Ladder (MW). Lane 2: Human HeLa and 293Trap cell lysates. Load: 15 µg . Block: 5% Skim Milk in 1X TBST. Primary Antibody: Rabbit Anti-WDFY3 Polyclonal Antibody  at 1:1000 for 1 hour at RT. Secondary Antibody: Goat Anti-Rabbit HRP at 1:2000 for 60 min at RT. Color Development: ECL solution for 6 min in RT. Predicted/Observed Size: 395.2 kDa. 100 μg Connectez-vous pour afficher 2 to 3 Days
$492.09
Détails
Humain Lapin Alkaline Phosphatase (AP) ICC, IF, WB Immunocytochemistry/Immunofluorescence analysis using Rabbit Anti-WDFY3 Polyclonal Antibody . Tissue: Colon carcinoma cell line (RKO). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Rabbit Anti-WDFY3 Polyclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Rabbit ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60 min at RT, 5 min at RT. Localization: Cytoplasm, Nucleus, Membrane. Magnification: 60X. (A) DAPI nuclear stain. (B) Phalloidin Texas Red F-Actin stain. (C) WDFY3 Antibody. (D) Composite. Western blot analysis of Human HeLa and 293Trap cell lysates showing detection of 395.2 kDa WDFY3 protein using Rabbit Anti-WDFY3 Polyclonal Antibody . Lane 1: Molecular Weight Ladder (MW). Lane 2: Human HeLa and 293Trap cell lysates. Load: 15 µg . Block: 5% Skim Milk in 1X TBST. Primary Antibody: Rabbit Anti-WDFY3 Polyclonal Antibody  at 1:1000 for 1 hour at RT. Secondary Antibody: Goat Anti-Rabbit HRP at 1:2000 for 60 min at RT. Color Development: ECL solution for 6 min in RT. Predicted/Observed Size: 395.2 kDa. 100 μg Connectez-vous pour afficher 2 to 3 Days
$494.62
Détails

anti-WDFY3 Anticorps mieux référencés

  1. Human Polyclonal WDFY3 Primary Antibody pour EM, ICC - ABIN315857 : Sommi, Necchi, Vitali, Montagna, De Luigi, Salmona, Ricci, Solcia: PaCS is a novel cytoplasmic structure containing functional proteasome and inducible by cytokines/trophic factors. dans PLoS ONE 2013 (PubMed)
    Show all 6 Pubmed References

  2. Human Monoclonal WDFY3 Primary Antibody pour ELISA, WB - ABIN949075 : Orosco, Ross, Cates, Scott, Wu, Sohn, Pleasure, Pleasure, Adamopoulos, Zarbalis: Loss of Wdfy3 in mice alters cerebral cortical neurogenesis reflecting aspects of the autism pathology. dans Nature communications 2014 (PubMed)

  3. Cow (Bovine) Polyclonal WDFY3 Primary Antibody pour WB - ABIN2784358 : Hillier, Graves, Fulton, Fulton, Pepin, Minx, Wagner-McPherson, Layman, Wylie, Sekhon, Becker, Fewell, Delehaunty, Miner, Nash, Kremitzki, Oddy, Du, Sun, Bradshaw-Cordum, Ali, Carter, Cordes, Harris et al.: Generation and annotation of the DNA sequences of human chromosomes 2 and 4. ... dans Nature 2005 (PubMed)
    Show all 2 Pubmed References

Plus d’anticorps contre WDFY3 partenaires d’interaction

Human WD Repeat and FYVE Domain Containing 3 (WDFY3) interaction partners

  1. we demonstrate that normally ALFY attenuates the canonical Wnt (Montrer WNT2 Anticorps) signaling pathway via autophagy-dependent removal specifically of aggregates of DVL3 (Montrer DVL3 Anticorps) and not of Dvl1 (Montrer DVL1 Anticorps) or Dvl2 (Montrer DVL2 Anticorps).

  2. ALFY binds selectively to LC3C (Montrer MAP1LC3C Anticorps) and the GABARAPs through a LC3 (Montrer MAP1LC3A Anticorps)-interacting region in its WD40 domain (Montrer DCAF12L2 Anticorps).

  3. increasing Alfy-mediated protein degradation may be beneficial in some organs, but may be detrimental in others

  4. Data suggest that p62 (Montrer GTF2H1 Anticorps) and ALFY interact to organize misfolded, ubiquitinated proteins into protein bodies that become degraded by autophagy.

  5. The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein Alfy.

  6. Alfy might target cytosolic protein aggregates for autophagic degradation.

Mouse (Murine) WD Repeat and FYVE Domain Containing 3 (WDFY3) interaction partners

  1. Data provide a novel association between WDFY3 and the RANKL (Montrer TNFSF11 Anticorps)-induced osteoclastogenesis pathway via the modulation of TRAF6 (Montrer TRAF6 Anticorps).

  2. Alfy translocalization likely is involved in the pathogenesis of amyotrophic lateral sclerosis.

  3. Wdfy3 is important in regulating neural progenitor divisions, neural migration, cerebral expansion and functional organization in the developing brain. Loss-of-function leads to pathological changes characteristic of autism spectrum disorders.

  4. gene expression profiling; in situ hybridization analysis revealed that the expressed BWF1 mRNA was restricted to the marginal region both in E14 (Montrer NPAT Anticorps) and E16 (Montrer SLC7A5 Anticorps) embryonic brain, but became diffuse after birth

WDFY3 profil antigène

Profil protéine

This gene encodes a phosphatidylinositol 3-phosphate-binding protein that functions as a master conductor for aggregate clearance by autophagy. This protein shuttles from the nuclear membrane to colocalize with aggregated proteins, where it complexes with other autophagic components to achieve macroautophagy-mediated clearance of these aggregated proteins. However, it is not necessary for starvation-induced macroautophagy.

Gene names and symbols associated with WDFY3

  • WDFY family member 4 (WDFY4) anticorps
  • WD repeat and FYVE domain containing 3 (WDFY3) anticorps
  • WD repeat and FYVE domain-containing protein 3 (MGYG_03998) anticorps
  • WD repeat and FYVE domain containing 3 (Wdfy3) anticorps
  • 2610509D04Rik anticorps
  • ALFY anticorps
  • AW319683 anticorps
  • B930017C24 anticorps
  • Bchs anticorps
  • BWF1 anticorps
  • D5Ertd66e anticorps
  • Ggtb3 anticorps
  • mKIAA0993 anticorps
  • ZFYVE25 anticorps

Protein level used designations for WDFY3

WD repeat and FYVE domain containing 3 , WD repeat and FYVE domain-containing protein 3 , autophagy-linked FYVE protein , beach domain, WD repeat and FYVE domain-containing protein 1 , galactosyltransferase 3 beta 1, 4

GENE ID SPECIES
100157904 Sus scrofa
461201 Pan troglodytes
10029110 Arthroderma gypseum CBS 118893
422613 Gallus gallus
23001 Homo sapiens
487841 Canis lupus familiaris
537096 Bos taurus
72145 Mus musculus
305164 Rattus norvegicus
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