anti-WNK Lysine Deficient Protein Kinase 3 (WNK3) Anticorps

WNK3 encodes a protein belonging to the 'with no lysine' family of serine-threonine protein kinases. De plus, nous expédions et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
WNK3 100363278  
WNK3 65267 Q9BYP7
WNK3 279561 Q80XP9
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Top anti-WNK3 Anticorps sur anticorps-enligne.fr

Showing 10 out of 95 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-WNK3 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:2500  Positive Control:  ACHN cell lysate Rabbit Anti-WNK3 antibody  Formalin Fixed Paraffin Embedded Tissue: Human Colon Primary antibody Concentration: 1:100 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20x Exposure Time: 0.5-2.0sec 100 μL 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué IF (p), IHC (p) Formalin-fixed and paraffin-embedded : human colon carcinoma labeled with Rabbit Anti-WNK3 protein Polyclonal Antibody (ABIN675713), Unconjugated 1:200 followed by conjugation to the secondary antibody Formalin-fixed and paraffin-embedded : human colon carcinoma labeled with Rabbit Anti-WNK3 protein Polyclonal Antibody (ABIN675713), Unconjugated 1:200 followed by conjugation to the secondary antibody 100 μL 3 to 7 Days
$317.90
Détails
Humain Lapin Inconjugué ELISA, IHC, WB Western blot analysis of Mouse brain lysate, using WNK3 Antibody. The lane on the left is treated with the antigen-specific peptide. ABIN6277649 at 1/100 staining Human brain cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL 11 to 12 Days
$390.77
Détails
Humain Lapin Inconjugué IHC, WB Western blot analysis of PRKWNK3 expression in rat brain (A) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Détails
Roussette (Chauve-souris) Lapin Inconjugué IHC, IHC (p), WB Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE). This image was taken for the unconjugated form of this product. Other forms have not been tested. 100 μL 11 to 14 Days
$727.83
Détails
Humain Lapin Inconjugué IHC (p), WB Western blot analysis in uterus tumor cell line lysates (35ug/lane). WNK3(PRKWNK3) Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL 2 to 3 Days
$515.63
Détails
Humain Lapin Inconjugué ELISA, IHC, WB 200 μL 12 to 14 Days
$438.90
Détails
Humain Lapin Inconjugué WB WNK3 antibody used at 1 ug/ml to detect target protein. 50 μg 9 to 11 Days
$449.29
Détails
Humain Lapin Inconjugué ELISA, IHC 200 μL 12 to 14 Days
$438.90
Détails
Humain Souris Inconjugué ELISA, WB Detection limit for recombinant GST tagged WNK3 is approximately 0.03ng/ml as a capture antibody. Western Blot detection against Immunogen (36.74 KDa) . 100 μg 11 to 12 Days
$440.00
Détails

anti-WNK3 Anticorps mieux référencés

  1. Human Polyclonal WNK3 Primary Antibody pour IP, WB - ABIN315865 : Haas, Cuddapah, Watkins, Rohn, Dy, Sontheimer: With-No-Lysine Kinase 3 (WNK3) stimulates glioma invasion by regulating cell volume. dans American journal of physiology. Cell physiology 2011 (PubMed)

Plus d’anticorps contre WNK3 partenaires d’interaction

Human WNK Lysine Deficient Protein Kinase 3 (WNK3) interaction partners

  1. This study demonstrated that the WNK3 up regulation in hippocampal specimens from epileptic patients with hippocampal sclerosis.

  2. Data show that WNK lysine deficient protein kinase 3 protein (WNK3) interacts with NCC and increases the Na-Cl cotransporter (NCC) expression on the cell membrane and in cytoplasm together.

  3. WNK3 enhances NCC protein expression by increasing NCC synthesis via an ERK 1/2-dependent signaling pathway

  4. WNK3 knockout mice exhibited significantly decreased infarct volume in a transgenic model of stroke and brain damage.

  5. There may be a novel role for WNK3 on the renal Na+-Cl-cotransporter (NCC) expression at the plasma membrane, an effect apparently independent of the SPAK kinase and the aldosterone-SGK1 pathway.

  6. LINGO-1 potentiates neuronal apoptosis, likely by inhibiting WNK3 kinase activity.

  7. WNK3 modulates intracellular Cl(-) concentration and regulatory volume decrease in HEK293 cells.

  8. The Wnk3 protein isoforms have a similar effect on SLC12 cotransporters. NKCC1/2 and NCC were inhibited, even in hypertonicity, while KCCs were activated, even in isotonic conditions.

  9. Analysis of the data showed that WNK3 is an essential regulator of NKCC1 and that WNK3 activates NKCC1-mediated ion transport necessary for cell volume changes associated with cell invasion.

  10. OXSR1 and WNK3 transcripts were substantially overexpressed in subjects with schizophrenia relative to comparison subjects.

  11. Data find that expression of the N termini of all four WNKs results in modest to strong activation of SGK1.

  12. WNK3 lies within the critical linkage interval for several human monogenic disorders, including X-linked mental retardation. The function of mammalian WNK3 kinase remains to be investigated.

  13. WNK3 is involved in promoting cell survival by a mechanism at the level of procaspase-3 activation.

  14. Results report that WNK3, another member of the WNK kinase family expressed by distal tubule cells, interacts with WNK4 and WNK1 to regulate NCC in both human kidney cells and Xenopus oocytes.

  15. Xp11.22 deletion including genes PHF8, FAM120C and WNK3 may be involved in the pathogenesis of autism.

  16. The positive effect of WNK3 on NCC also requires its catalytic activity

  17. WNK3 is a positive regulator of the transcellular Ca2+ transport pathway (TRPV5 and TRPV6).

  18. The C-terminal motifs contributed by exons 18 and 22 play an important role in the actions of WNK3 isoforms on NCCT.

Mouse (Murine) WNK Lysine Deficient Protein Kinase 3 (WNK3) interaction partners

  1. WNK3 knockout mice show faster neurological functional recovery after occlusion of the left middle cerebral artery.

  2. angiotensin II activates the WNK-SPAK-NKCC1 phosphorylation cascade through the angiotensin II type 1 receptor. activation of the WNK-SPAK-NKCC1 phosphorylation cascade induced by a low-salt diet and angiotensin II is dependent on WNK3.

  3. WNK3 may serve as a member of a kinase network that facilitates the fine-tuning of renal transepithelial NaCl transport.

  4. WNK3 increases the cytoplasmic localization of Fox-1, thereby suppressing Fox-1-dependent mrna splicing.

  5. suggest that WNK3 is part of the Cl(-)/volume-sensing mechanism necessary for the maintenance of cell volume during osmotic stress and the dynamic modulation of GABA neurotransmission

  6. effects of WNK3 on these transporters and their coexpression in renal epithelia implicate WNK3 in NaCl, water, and blood pressure homeostasis, perhaps via signaling downstream of vasopressin

  7. WNK3 is likely a component of one of the mechanisms that determines the balance between renal NaCl reabsorption and K+ secretion.

WNK3 profil antigène

Profil protéine

This gene encodes a protein belonging to the 'with no lysine' family of serine-threonine protein kinases. These family members lack the catalytic lysine in subdomain II, and instead have a conserved lysine in subdomain I. This family member functions as a positive regulator of the transcellular Ca2+ transport pathway, and it plays a role in the increase of cell survival in a caspase-3-dependent pathway. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with WNK3

  • wu:fc63h12 (wu:fc63h12) anticorps
  • WNK lysine deficient protein kinase 3 (LOC100363278) anticorps
  • WNK lysine deficient protein kinase 3 (WNK3) anticorps
  • WNK lysine deficient protein kinase 3 (Wnk3) anticorps
  • fc63h12 anticorps
  • Prkwnk3 anticorps
  • RGD1563131 anticorps
  • Wnk3-ps anticorps

Protein level used designations for WNK3

wu:fc63h12 , WNK lysine deficient protein kinase 3 , protein kinase with no lysine 3 , serine/threonine-protein kinase WNK3 , WNK lysine deficient protein kinase 3, pseudogene , protein kinase lysine-deficient 3

GENE ID SPECIES
325273 Danio rerio
100363278 Rattus norvegicus
65267 Homo sapiens
279561 Mus musculus
100337119 Bos taurus
317420 Rattus norvegicus
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