Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) Protéines
The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton.
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Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 2-502) protein (His tag) Protein
Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 39-251) protein (T7 tag,His tag) Protein
Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 1-298) protein (T7 tag,His tag) Protein
Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 57-170) protein (GST tag) Protein
Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) Protéine Protein
Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) Protéine Protein
Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) protein (Myc-DYKDDDDK Tag) Protein
Profil protéine Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS)
Profil protéine
The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. Wiskott-Aldrich syndrome is a rare, inherited, X-linked, recessive disease characterized by immune dysregulation and microthrombocytopenia, and is caused by mutations in the WAS gene. The WAS gene product is a cytoplasmic protein, expressed exclusively in hematopoietic cells, which show signalling and cytoskeletal abnormalities in WAS patients. A transcript variant arising as a result of alternative promoter usage, and containing a different 5' UTR sequence, has been described, however, its full-length nature is not known.
Gene names and symbols associated with WAS
- Wiskott-Aldrich syndrome (WAS) anticorps
- neural Wiskott-Aldrich syndrome protein (LOC5578888) anticorps
- wiskott-aldrich syndrome protein (CpipJ_CPIJ006699) anticorps
- Wiskott-Aldrich syndrome (Was) anticorps
- Wiskott-Aldrich syndrome L homeolog (was.L) anticorps
- Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b (wasb) anticorps
- imd2 anticorps
- SCNX anticorps
- thc anticorps
- thc1 anticorps
- U42471 anticorps
- was anticorps
- wasp anticorps
- wu:fk81c08 anticorps
- zgc:64164 anticorps
Protein level used designations for WAS
eczema-thrombocytopenia , thrombocytopenia 1 (X-linked) , wiskott-Aldrich syndrome protein , wiskott-aldrich syndrome protein , Wiskott-Aldrich syndrome homolog , wiskott-Aldrich syndrome protein homolog , Wiskott-Aldrich syndrome (eczema-thrombocytopenia) , Wiskott-Aldrich syndrome L homeolog , wiskott-Aldrich syndrome L homeolog , wasp1
| GENE ID | SPECIES |
|---|---|
| 7454 | Homo sapiens |
| 5578888 | Aedes aegypti |
| 6038460 | Culex quinquefasciatus |
| 22376 | Mus musculus |
| 317371 | Rattus norvegicus |
| 100037214 | Xenopus laevis |
| 335158 | Danio rerio |
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