anti-Zinc Finger, MYM-Type 2 (ZMYM2) Anticorps

The protein encoded by ZMYM2 is a zinc finger protein that may act as a transcription factor. De plus, nous expédions et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
ZMYM2 7750 Q9UBW7
ZMYM2 76007 Q9CU65
ZMYM2 305913  
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Top anti-ZMYM2 Anticorps sur anticorps-enligne.fr

Showing 10 out of 45 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Humain Lapin Inconjugué ICC, IF, IHC (p), WB WB Image Sample (20 ug of whole cell lysate) A: human ESC 5% SDS PAGE antibody diluted at 1:1000 ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed Human ESC, using ZNF198, antibody at 1:1000 dilution. 100 μL 3 to 4 Days
$466.18
Détails
Poulet Lapin Inconjugué IHC, IHC (p), WB Human Breast (formalin-fixed, paraffin-embedded) stained with ZMYM2 antibody ABIN297886 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-ZMYM2 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. 50 μg 11 to 14 Days
$484.00
Détails
Humain Lapin Inconjugué IHC, IHC (p), WB Anti-ZMYM2 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody ABIN959704 concentration 5 ug/ml. Anti-ZMYM2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 0.05 mg 11 to 14 Days
$484.00
Détails
Poulet Lapin Inconjugué IHC (p), WB 50 μg 6 to 8 Days
$495.00
Détails
Humain Lapin Inconjugué EIA, WB   0.1 mg 4 to 8 Days
$522.50
Détails
Boeuf (Vache) Lapin Inconjugué IF, IHC, IHC (p), IP, WB Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL 11 to 14 Days
$639.83
Détails
Humain Lapin Inconjugué IHC (p), WB 50 μg 12 to 14 Days
$686.14
Détails
Humain Lapin Inconjugué IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Anti-ZMYM2/ZNF198 Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat testis labeled with Anti-ZMYM2/ZNF198 Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL 14 to 21 Days
$317.90
Détails
Boeuf (Vache) Lapin Inconjugué IF, IHC, IHC (p) Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) 100 μL 11 to 14 Days
$625.17
Détails
Humain Lapin Inconjugué IHC (p) Immunochemical staining of human ZMYM2 in human breast carcinoma with rabbit polyclonal antibody (0.3 µg/mL, formalin-fixed paraffin embedded sections). Immunochemical staining of human ZMYM2 in human brain with rabbit polyclonal antibody (0.3 µg/mL, formalin-fixed paraffin embedded sections). 100 μL 14 to 16 Days
$247.82
Détails

anti-ZMYM2 Anticorps mieux référencés

  1. Human Polyclonal ZMYM2 Primary Antibody pour ICC, IF - ABIN4367041 : Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. dans Nature methods 2013 (PubMed)

Plus d’anticorps contre ZMYM2 partenaires d’interaction

Human Zinc Finger, MYM-Type 2 (ZMYM2) interaction partners

  1. study found that ZMYM2-FLT3 and DIAPH1-PDGFRB fusion genes are novel, cytogenetically cryptic and therapeutically targetable abnormalities in myeloproliferative neoplasms with eosinophilia, and are thus reminiscent of FIP1L1-PDGFRA positive myeloid neoplasms

  2. In this report we described the first successful development of a model of human ZMYM2-FGFR1 driven AML in immunocompromised mice, which shows an etiology consistent with the development of the primary human disease.

  3. Multi-SUMO binding is mediated through multi-SIM modules, and the functional importance of these interactions is demonstrated for the transcriptional corepressor ZMYM2/ZNF198

  4. downregulation of SUZ12 and ZNF198 leads to epigenetic reprogramming of infected hepatocytes. Because both Plk1 and HOTAIR are elevated in many human cancers, we propose that their combined effects are involved in epigenetic reprogramming

  5. B-lymphoblastic leukemia/lymphoma associated with t(8;13)(p11;q12)/ ZMYM2 (ZNF198)-FGFR1

  6. We propose Plk1 activity down-regulates ZNF198 and SUZ12, thereby enhancing both HBV replication and pX-mediated oncogenic transformation.

  7. cell transformation mediated by ZNF198-FGFR1 requires STAT5 activation

  8. ZNF198/fibroblast growth factor receptor-1 has signaling function comparable with interleukin-6 cytokine receptors.

  9. SUMO-1, PML and ZNF198 colocalize to punctate structures, shown by immunocytochemistry to be PML bodies.

  10. ZNF198-FGFR1 activated both the AKT and mitogen activated protein kinase (MAPK) prosurvival signaling pathways, resulting in elevated phosphorylation of the AKT target FOXO3a at T32 and BAD at S112, respectively.

  11. HSPA1A is an important regulator of the stability and function of ZNF198 and its oncogenic derivative, ZNF198-FGFR1.

  12. ZNF198, through its multiple protein-protein interaction interfaces, helps to maintain the intact LSD1-CoREST-HDAC1 complex on specific, non-REST-responsive promoters and may also prevent SUMO-dependent dissociation of HDAC1

  13. An important event in the process of ZNF198-FGFR1-induced T-cell leukemia.

  14. ZNF198-FGFR1 is associated with phosphorylation of several proteins including SSBP2, ABL, FLJ14235, CALM and TRIM4 proteins.

Mouse (Murine) Zinc Finger, MYM-Type 2 (ZMYM2) interaction partners

  1. The study demonstrates frequent, constitutive activation of Notch1 and its downstream target genes in T-cell lymphomas that arose in a murine model of Zmym2-Fgfr1 stem cell leukemia-lymphoma syndrome.

ZMYM2 profil antigène

Profil protéine

The protein encoded by this gene is a zinc finger protein that may act as a transcription factor. The encoded protein may be part of a BHC histone deacetylase complex. Translocation of this gene with the fibroblast growth factor receptor-1 gene (FGFR1) results in a fusion gene, which may be a cause of stem cell leukemia lymphoma syndrome (SCLL). Several transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with ZMYM2

  • zinc finger MYM-type containing 2 (ZMYM2) anticorps
  • zinc finger, MYM-type 2 (zmym2) anticorps
  • zinc finger MYM-type containing 2 (zmym2) anticorps
  • zinc finger MYM-type containing 2 L homeolog (zmym2.L) anticorps
  • zinc finger, MYM-type 2 (Zmym2) anticorps
  • zinc finger, MYM-type 2 (ZMYM2) anticorps
  • zinc finger MYM-type containing 2 (Zmym2) anticorps
  • 5830413P05Rik anticorps
  • fc07a10 anticorps
  • FIM anticorps
  • MGC83724 anticorps
  • MYM anticorps
  • RAMP anticorps
  • SCLL anticorps
  • si:dkey-51d17.6 anticorps
  • wu:fc07a10 anticorps
  • Zfp198 anticorps
  • ZMYM2 anticorps
  • Znf198 anticorps

Protein level used designations for ZMYM2

zinc finger, MYM-type 2 , zinc finger protein 198 , fused in myeloproliferative disorders protein , rearranged in an atypical myeloproliferative disorder , zinc finger MYM-type protein 2 , MYM-type zinc finger protein 2

GENE ID SPECIES
452454 Pan troglodytes
570149 Danio rerio
721255 Macaca mulatta
100144668 Xenopus (Silurana) tropicalis
446388 Xenopus laevis
7750 Homo sapiens
76007 Mus musculus
418954 Gallus gallus
100174301 Pongo abelii
477346 Canis lupus familiaris
508731 Bos taurus
305913 Rattus norvegicus
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