anti-Zyxin (ZYX) Anticorps

Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. De plus, nous expédions Zyxin Protéines (9) et Zyxin Kits (8) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
ZYX 7791 Q15942
ZYX 22793 Q62523
ZYX 114636  
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Top anti-Zyxin Anticorps sur anticorps-enligne.fr

Showing 10 out of 86 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Poulet Souris Inconjugué IF, IP, IHC, WB Western blot analysis of Zyxin on SL-29 cell lysate. Lane 1: 1:2500, lane 2: 1:5000, lane 3: 1:10000 dilution of anti-Zyxin. Immunofluorescent staining of chick fibroblasts. 50 μg Connectez-vous pour afficher 6 to 8 Days
$168.74
Détails
Boeuf (Vache) Lapin Inconjugué WB <b>WB Suggested Anti-ZYX Antibody Titration: </b>1.25ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>Jurkat cell lysate Sample Type: HeLa whole cell lysatePrimary Dilution: 1:200 100 μL Connectez-vous pour afficher 2 to 3 Days
$229.00
Détails
Humain Souris Inconjugué ICC, IP, WB 100 μg Connectez-vous pour afficher 5 to 6 Days
$487.03
Détails
Humain Lapin Inconjugué ELISA, WB Western blot analysis of extracts from Jurkat cells treated with paclitaxel 1uM 24h, using Zyxin (Phospho-Ser142) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 2 to 3 Days
$302.50
Détails
Humain Souris Inconjugué WB Western blot analysis of ZYX over-expressed 293 cell line, cotransfected with ZYX Validated Chimera RNAi used as specificity and loading control. Western Blot analysis of ZYX expression in transfected 293T cell line by ZYX monoclonal antibody (M01), clone 2C10-4A7. Lane 1: ZYX transfected lysate(61.3 KDa). Lane 2: Non-transfected lysate. 0.1 mg Connectez-vous pour afficher 8 to 11 Days
$450.00
Détails
Humain Chèvre Inconjugué ELISA, WB 0.1 mg Connectez-vous pour afficher 2 to 3 Days
$481.25
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: Zyxin Antibody  - Immunofluorescent staining of human cell line U-2 OS shows localization to focal adhesion sites. Immunohistochemistry-Paraffin: Zyxin Antibody  - Staining of human spleen shows strong cytoplasmic positivity in cells in red pulp. 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$491.63
Détails
Roussette (Chauve-souris) Lapin Inconjugué WB 100 μg Connectez-vous pour afficher 7 to 9 Days
$493.17
Détails
Roussette (Chauve-souris) Chèvre Inconjugué ELISA, WB 100 μg Connectez-vous pour afficher 7 to 9 Days
$610.50
Détails

ZYX Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-Zyxin Anticorps mieux référencés

  1. Human Monoclonal ZYX Primary Antibody pour ICC, IP - ABIN1742558 : Mori, Nakagami, Koibuchi, Miura, Takami, Koriyama, Hayashi, Sabe, Mochizuki, Morishita, Kaneda: Zyxin mediates actin fiber reorganization in epithelial-mesenchymal transition and contributes to endocardial morphogenesis. dans Molecular biology of the cell 2009 (PubMed)
    Show all 11 Pubmed References

  2. Chicken Monoclonal ZYX Primary Antibody pour IF, IP - ABIN968016 : Drees, Friederich, Fradelizi, Louvard, Beckerle, Golsteyn: Characterization of the interaction between zyxin and members of the Ena/vasodilator-stimulated phosphoprotein family of proteins. dans The Journal of biological chemistry 2000 (PubMed)
    Show all 5 Pubmed References

  3. Human Monoclonal ZYX Primary Antibody pour IF, IP - ABIN563471 : Hirata, Tatsumi, Sokabe: Mechanical forces facilitate actin polymerization at focal adhesions in a zyxin-dependent manner. dans Journal of cell science 2008 (PubMed)
    Show all 2 Pubmed References

  4. Human Monoclonal ZYX Primary Antibody pour IHC (p), ELISA - ABIN521634 : Mise, Savai, Yu, Schwarz, Kaminski, Eickelberg: Zyxin is a transforming growth factor-? (TGF-?)/Smad3 target gene that regulates lung cancer cell motility via integrin ?5?1. dans The Journal of biological chemistry 2012 (PubMed)

  5. Human Polyclonal ZYX Primary Antibody pour ELISA, WB - ABIN4367694 : Li, Zhuang, Trueb: Zyxin interacts with the SH3 domains of the cytoskeletal proteins LIM-nebulette and Lasp-1. dans The Journal of biological chemistry 2004 (PubMed)

  6. Human Polyclonal ZYX Primary Antibody pour ICC, IF - ABIN4367697 : Fukumoto, Kurisu, Yamada, Takenawa: α-Actinin-4 enhances colorectal cancer cell invasion by suppressing focal adhesion maturation. dans PLoS ONE 2015 (PubMed)

  7. Cow (Bovine) Polyclonal ZYX Primary Antibody pour WB - ABIN2775766 : Moody, Grange, Ascione, Boothe, Bushnell, Hansen: A zyxin head-tail interaction regulates zyxin-VASP complex formation. dans Biochemical and biophysical research communications 2008 (PubMed)
    Show all 2 Pubmed References

Plus d’anticorps contre Zyxin partenaires d’interaction

Caenorhabditis elegans (C. elegans) Zyxin (ZYX) interaction partners

  1. ZYX-1 is a conserved LIM (Montrer PDLIM5 Anticorps) domain-containing focal adhesion protein that regulates synapse maintenance in Caenorhabditis elegans

  2. The zyx-1 gene encodes two different isoforms, ZYX-1a and ZYX-1b, which exhibit different roles in dystrophin (Montrer DMD Anticorps)-dependent muscle degeneration in C. elegans

  3. DYC-1 interacts with ZYX-1, the homologue of the vertebrate focal adhesion LIM domain protein (Montrer PDLIM7 Anticorps) zyxin.

Fruit Fly (Drosophila melanogaster) Zyxin (ZYX) interaction partners

  1. results show that Zyxin is a functional antagonist of Expanded in growth control

  2. The motor domain of DmMyo20 could specifically bind to actin (Montrer ACTB Anticorps) filaments in an ATP-independent manner and enhance the interaction between actin (Montrer ACTB Anticorps) filaments and Zyx102, a downstream component of DmMyo20 in the Fat signaling pathway.

  3. Through epistasis tests, the requirement for Zyx is positioned within the Fat branch of Hippo signaling, downstream of Fat and Dco (Montrer CSNK1E Anticorps), and upstream of the Yorkie (Montrer YAP1 Anticorps) kinase Warts.

  4. Reduction of Zyx102 protein levels using RNA-interference results in lethality at the pharate adult stage.

Human Zyxin (ZYX) interaction partners

  1. Increased zyxin expression is associated with asthma.

  2. VASP (Montrer VASP Anticorps), zyxin and TES (Montrer TES Anticorps) are tension-dependent members of focal adherens junctions independent of the alpha-catenin (Montrer CTNNA1 Anticorps)-vinculin (Montrer VCL Anticorps) module.

  3. Zyxin binding to Ptc2 (Montrer PTCH2 Anticorps) is due to the interaction of Zyxin 2nd LIM (Montrer PDLIM5 Anticorps)-domain (530-590 aa) with the under-membrane region of the cytoplasmic C-terminus of Ptc2 (Montrer PTCH2 Anticorps) (1159-1412 aa).

  4. ZYX gene may be aging-related gene and involved in Osteoporosis.

  5. Matrix density alters zyxin phosphorylation, which limits peripheral process formation and extension in endothelial cells invading 3D collagen matrices.

  6. Zyxin, which is thought to be essential for tight cell-to-cell junctions, decreased 1.8-fold in TNF-alpha (Montrer TNF Anticorps)-treated human brain microvascular endothelial cells.

  7. Integrin-beta5 and zyxin mediate formation of ventral stress fibers in response to transforming growth factor beta.

  8. Zyxin is a novel target for beta-amyloid peptide (Montrer APP Anticorps) activities in Alzheimer's disease.

  9. Zyxin is suggested to promote growth, migration and invasiveness of fibroblastic type oral squamous cell carcinoma cells by upregulating Rac1 and Cdc42 (Montrer CDC42 Anticorps).

  10. A stretch-induced signaling pathway in vascular cells leads to the activation of zyxin, a cytoskeletal protein (Montrer ACTN1 Anticorps) specifically involved in transducing mechanical stimuli.

Mouse (Murine) Zyxin (ZYX) interaction partners

  1. zyxin influences focal adhesion dynamics, that it recruits Tes (Montrer TES Anticorps) and that this interaction is functional in regulating cell spreading.

  2. Zyxin contributes to the migratory and invasive phenotype evoked by Tead2 (Montrer TEAD2 Anticorps).

  3. Integrin-beta5 and zyxin mediate formation of ventral stress fibers in response to transforming growth factor beta.

  4. paxillin (Montrer PXN Anticorps) and zyxin are LIM (Montrer PDLIM5 Anticorps)-domain adaptor proteins that are recruited to stress fiber strain sites

  5. Zyxin regulates migration of renal epithelial cells through activation of hepatocyte nuclear factor-1beta.

  6. Zyxin is a transforming growth factor-beta (TGF-beta)/Smad3 (Montrer SMAD3 Anticorps) target gene that regulates lung cancer cell motility via integrin alpha5beta1.

  7. a bipartite mechanism for stretch-induced actin remodeling involves mechanosensitive targeting of zyxin to actin stress fibers and localized recruitment of actin regulatory machinery

  8. Mice that lack zyxin function are viable and fertile and display no obvious histological abnormalities in any of the organs examined.Specifically, we evaluated blood platelet function, nervous system development, and skin architecture

  9. LIM-nebulette (Montrer NEBL Anticorps), Lasp-1 (Montrer LASP1 Anticorps), and zyxin may play an important role in the organization of focal adhesions

  10. Cooperates with Ena, vasodilator-stimulated phosphoprotein, and caldesmon to influence integrin-dependent cell motility and actin stress fiber remodeling.

Xenopus laevis Zyxin (ZYX) interaction partners

  1. Zyxin binding to Ptc2 (Montrer PTCH2 Anticorps) is due to the interaction of Zyxin 2nd LIM (Montrer PDLIM5 Anticorps)-domain (530-590 aa) with the under-membrane region of the cytoplasmic C-terminus of Ptc2 (Montrer PTCH2 Anticorps) (1159-1412 aa).

  2. Zyxin inhibits Shh (Montrer SHH Anticorps) signaling during the CNS patterning in Xenopus laevis through interaction with Gli1 (Montrer GLI1 Anticorps)

  3. These results are consistent with a possible role of Zyxin as a negative modulator of Xanf1 transcriptional repressing activity.

  4. binding of the LIM2 domain of zyxin with the Engrailed Homology 1 repressor domain of Xanf1 is responsible for the interaction of these proteins.

Zyxin (ZYX) profil antigène

Profil protéine

Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform.

Gene names and symbols associated with anti-Zyxin (ZYX) Anticorps

  • Zyxin (zyx-1) anticorps
  • Zyxin (Zyx) anticorps
  • zyxin (zyx) anticorps
  • zyxin (ZYX) anticorps
  • zyxin (EDI_201420) anticorps
  • zyxin (Zyx) anticorps
  • zyxin S homeolog (zyx.S) anticorps
  • 9530098H06Rik anticorps
  • BcDNA:LD06023 anticorps
  • CG32018 anticorps
  • DLim-1 anticorps
  • Dmel\\CG32018 anticorps
  • DmLIM-1 anticorps
  • ESP-2 anticorps
  • HED-2 anticorps
  • lim anticorps
  • Lim102EF anticorps
  • MGC145270 anticorps
  • R75157 anticorps
  • zgc:171680 anticorps
  • zyx anticorps
  • zyx102 anticorps
  • Zyx102EF anticorps
  • zyxin anticorps

Protein level used designations for anti-Zyxin (ZYX) Anticorps

ZYXin family member (zyx-1) , CG32018-PA , CG32018-PB , CG32018-PG , CG32018-PH , Zyx-PA , Zyx-PB , Zyx-PG , Zyx-PH , Zyx102EF , zyxin , hypothetical protein LOC779718 , zyxin-2

GENE ID SPECIES
174951 Caenorhabditis elegans
317824 Drosophila melanogaster
564246 Danio rerio
706407 Macaca mulatta
779718 Xenopus (Silurana) tropicalis
5914189 Entamoeba dispar SAW760
100011992 Monodelphis domestica
100219276 Taeniopygia guttata
7791 Homo sapiens
768226 Bos taurus
22793 Mus musculus
114636 Rattus norvegicus
482736 Canis lupus familiaris
100524720 Sus scrofa
418300 Gallus gallus
100049724 Xenopus laevis
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