alpha Hemoglobin Stabilizing Protein (aHSP) Kits ELISA

Act as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. De plus, nous expédions aHSP Anticorps (52) et aHSP Protéines (15) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
aHSP 51327 Q9NZD4
aHSP 170812 Q9CY02
aHSP 293522  
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Showing 10 out of 26 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Fournisseur Livraison Prix Détails
Humain 13.3 pg/mL 31.2 pg/mL - 2000 pg/mL 96 Tests Connectez-vous pour afficher 13 to 16 Days
$663.16
Détails
Souris 0.312-20 ng/mL   96 Tests Connectez-vous pour afficher 2 to 3 Days
$713.90
Détails
Cobaye 0.094 ng/mL 0.156-10 ng/mL   96 Tests Connectez-vous pour afficher 12 to 14 Days
$715.00
Détails
Lapin 37.5 pg/mL 62.5-4000 pg/mL   96 Tests Connectez-vous pour afficher 12 to 14 Days
$715.00
Détails
Poulet 0.094 ng/mL 0.156-10 ng/mL   96 Tests Connectez-vous pour afficher 12 to 14 Days
$715.00
Détails
Porc 0.094 ng/mL 0.156-10 ng/mL   96 Tests Connectez-vous pour afficher 12 to 14 Days
$715.00
Détails
Singe 0.094 ng/mL 0.156-10 ng/mL   96 Tests Connectez-vous pour afficher 12 to 14 Days
$715.00
Détails
Rat < 0.57 ng/mL 1.56 ng/mL - 100 ng/mL   96 Tests Connectez-vous pour afficher 11 to 18 Days
$824.38
Détails
Rat < 0.57 ng/mL 1.56 ng/mL - 100 ng/mL   96 Tests Connectez-vous pour afficher 11 to 18 Days
$838.60
Détails
Souris < 13.8 pg/mL 31.2 pg/mL - 2000 pg/mL   96 Tests Connectez-vous pour afficher 11 to 18 Days
$867.02
Détails

Plus Kits ELISA pour aHSP partenaires d'interaction

Human alpha Hemoglobin Stabilizing Protein (aHSP) interaction partners

  1. In the presence of free alpha subunits and H2O2, both HbA and HbE (Montrer HBe1 Kits ELISA) showed bCys93 oxidation which increased with higher H2O2 concentrations. In the presence of Alpha-hemoglobin stabilizing protein (AHSP)Cys93 oxidation was substantially reduced in both proteins.in the presence of excess free alpha-subunit (Montrer POLG Kits ELISA) and under the same oxidative conditions, these events are substantially increased for HbE (Montrer HBe1 Kits ELISA) compared to HbA

  2. Findings indicate that alpha-hemoglobin-stabilizing protein (AHSP) expression is a biomarker of hemoglobin (Montrer HBB Kits ELISA) H (HbH (Montrer HBA1 Kits ELISA)) disease severity and infer an important role of AHSP in modulating the pathophysiology of this disease.

  3. AHSP is predominantly expressed in erythroid precursors in bone marrow biopsy specimens from patients with hematologic malignancies.

  4. AHSP expression was higher in patients with sickle cell anemia versus thalassemia, with no significant difference between BTM and BTI. Expression was higher in patients with NTDT and on hydroxyurea therapy.

  5. In maturing RBC (Montrer CACNA1C Kits ELISA) progenitors AHSP bind to free alpha-globin (Montrer HBA1 Kits ELISA) chains to increase the HbA production. (Review)

  6. analysis showed binding of STAT3 (Montrer STAT3 Kits ELISA) to AHSP promoter and binding was significantly augmented with IL6 (Montrer IL6 Kits ELISA) stimulation and upon alpha-globin (Montrer HBA1 Kits ELISA) overexpression

  7. The relationship between AHSP gene expression, disease severity, and the beta/alpha globin (Montrer HBA1 Kits ELISA) mRNA ratio was studied among different homozygote beta-thalassemia patients.

  8. alpha-Hemoglobin-stabilizing protein (AHSP) perturbs the proximal heme pocket of oxy (Montrer GCG Kits ELISA)-alpha-hemoglobin and weakens the iron-oxygen bond.

  9. alpha-Hemoglobin stabilizing protein (AHSP) markedly decreases the redox potential and reactivity of alpha-subunits of human HbA with hydrogen peroxide.

  10. AHSP acts as a molecular chaperone (Montrer HSP90AA1 Kits ELISA) by rapidly binding and stabilizing met-alpha hemichrome folding intermediates

Mouse (Murine) alpha Hemoglobin Stabilizing Protein (aHSP) interaction partners

  1. role of alpha-hemoglobin stabilizing protein in hemoglobin assembly

  2. Endogenous AHSP is not limiting for alpha-globin (Montrer HBA-A1 Kits ELISA) detoxification in beta-thalassemic mice.

  3. activin A (Montrer INHBA Kits ELISA) does not appear to affect the exocrine or endocrine components of the pancreas, but promotes differentiation of pancreatic tissue into intestine via a Shh (Montrer SHH Kits ELISA)-dependent mechanism

  4. Loss of AHSP impairs erythropoiesis and exacerbates beta-thalassemia.

  5. These results support the hypothesis that EKLF (Montrer KLF1 Kits ELISA) acts as a transcription factor and a chromatin modulator for the AHSP and beta-globin (Montrer HBB Kits ELISA) genes and indicate that EKLF (Montrer KLF1 Kits ELISA) may play similar roles for other erythroid genes.

  6. developmental stage- and differentiation state-specific regulation of the nuclear transport of EKLF (Montrer KLF1 Kits ELISA) might be one of the steps necessary for the switch-on of the mammalian adult beta globin (Montrer HBB Kits ELISA) gene transcription

  7. AHSP also acts as a molecular chaperone to stabilize nascent alpha-globin for hemoglobin A assembly

  8. The expression of AHSP in a subclone of murine erythroleukemia cells in relationship to prion protein (Montrer PRNP Kits ELISA) on the cell surface is reported.

aHSP profil antigène

Antigen Summary

Act as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. Specifically protects free alpha-hemoglobin from precipitation (By similarity).

Gene names and symbols associated with aHSP

  • alpha hemoglobin stabilizing protein (AHSP) anticorps
  • alpha hemoglobin stabilizing protein (Ahsp) anticorps
  • alpha-hemoglobin-stabilizing protein-like (LOC100620111) anticorps
  • AHSP anticorps
  • EDRF anticorps
  • Eraf anticorps

Protein level used designations for aHSP

alpha hemoglobin stabilizing protein , erythroid associated factor , alpha hemoglobin stabilising protein , alpha-hemoglobin-stabilizing protein , erythroid differentiation associated factor , erythroid differentiation-related factor , erythroid-associated factor

GENE ID SPECIES
454073 Pan troglodytes
714392 Macaca mulatta
100127218 Ovis aries
100340962 Oryctolagus cuniculus
51327 Homo sapiens
170812 Mus musculus
338381 Bos taurus
293522 Rattus norvegicus
100712877 Cavia porcellus
100620111 Sus scrofa
Fournisseurs de qualité sélectionnés pour aHSP (aHSP) Kits ELISA
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