anti-phosphodiesterase 6D, CGMP-Specific, Rod, delta (PDE6D) Anticorps

Acts as a GTP specific dissociation inhibitor (GDI). De plus, nous expédions phosphodiesterase 6D, CGMP-Specific, Rod, delta Protéines (9) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
PDE6D 363272  
PDE6D 5147 O43924
PDE6D 18582 O55057
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Top anti-phosphodiesterase 6D, CGMP-Specific, Rod, delta Anticorps sur anticorps-enligne.fr

Showing 10 out of 36 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué ICC, IF, IHC (p), WB ICC/IF Image Immunofluorescence analysis of methanol-fixed HeLa, using PDE6D, antibody at 1:500 dilution. WB Image Sample (30 ug of whole cell lysate) A: MOLT4 , 12% SDS PAGE antibody diluted at 1:1000 100 μL Connectez-vous pour afficher 3 to 4 Days
$466.18
Détails
Humain Lapin Inconjugué WB PDE6D Antibody (Center)  western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the PDE6D antibody detected the PDE6D protein (arrow). PDE6D Antibody (Center)  western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the PDE6D antibody detected the PDE6D protein (arrow). 400 μL Connectez-vous pour afficher 10 to 11 Days
$385.00
Détails
Humain Lapin Inconjugué WB Western blot analysis in A2058 cell line lysates (35ug/lane). Western blot analysis in mouse heart tissue lysates (35ug/lane). 400 μL Connectez-vous pour afficher 2 to 3 Days
$515.63
Détails
Humain Souris Inconjugué IF, ELISA, WB PDE6D monoclonal antibody (M06), clone 5C7 Western Blot analysis of PDE6D expression in HeLa . Immunofluorescence of monoclonal antibody to PDE6D on HeLa cell. [antibody concentration 20 ug/ml] 100 μg Connectez-vous pour afficher 11 to 12 Days
$440.00
Détails
Boeuf (Vache) Lapin Inconjugué WB   100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué WB Western blot analysis of extracts of various cell lines, using PDE6D antibody. 200 μL Connectez-vous pour afficher 12 to 14 Days
$438.90
Détails
Humain Lapin Inconjugué ICC, IHC, IHC (p), WB   100 μL Connectez-vous pour afficher 11 to 14 Days
$537.17
Détails
Souris Lapin Inconjugué ICC, IF, IHC, IHC (fro), WB   100 μg Connectez-vous pour afficher 11 to 14 Days
$639.83
Détails
Humain Lapin Inconjugué ELISA, WB   200 μL Connectez-vous pour afficher 11 to 16 Days
$658.43
Détails
Humain Lapin Inconjugué IF/ICC, IHC (fp), WB   100 μL Connectez-vous pour afficher 6 to 8 Days
$431.20
Détails

anti-phosphodiesterase 6D, CGMP-Specific, Rod, delta Anticorps mieux référencés

  1. Human Polyclonal PDE6D Primary Antibody pour IHC, IHC (p) - ABIN4344439 : Thomas, Wright, Le Corre, Micalizzi, Romani, Abhyankar, Saada, Perrault, Amiel, Litzler, Filhol, Elkhartoufi, Kwong, Casanova, Boddaert, Baehr, Lyonnet, Munnich, Burglen, Chassaing, Encha-Ravazi et al.: A homozygous PDE6D mutation in Joubert syndrome impairs targeting of farnesylated INPP5E protein to the primary cilium. ... dans Human mutation 2014 (PubMed)

Plus d’anticorps contre phosphodiesterase 6D, CGMP-Specific, Rod, delta partenaires d’interaction

Human phosphodiesterase 6D, CGMP-Specific, Rod, delta (PDE6D) interaction partners

  1. PDE6delta binds selectively to the C-terminus of RPGR and that this interaction is critical for RPGR's localization to cilia.

  2. Studies indicate that the binding of UNC119 and PDE6D, to the lipid-modified ciliary cargo and the specific release of the cargo in the cilia by the ciliary small G-protein Arl3 in a GTP-dependent manner.

  3. Study identifies PDE6D as a novel Joubert syndrome gene and provides the first evidence of prenyl-binding-dependent trafficking in ciliopathies.

  4. RPGR is acting as a scaffold protein recruiting cargo-loaded PDE6D and Arl3 to release lipidated cargo into cilia.

  5. findings indicate that ARL13B, INPP5E, PDE6D, and CEP164 form a distinct functional network that is involved in JBTS and NPHP but independent of the ones previously defined by NPHP and MKS proteins

  6. Data show that PDEdelta activity augments K/Hras signalling by enriching Ras at the plasma membrane.

Cow (Bovine) phosphodiesterase 6D, CGMP-Specific, Rod, delta (PDE6D) interaction partners

  1. Results suggest that PrBP/delta exclusively interacts with the soluble fraction of PDE6.

  2. The modest levels of basal activity exhibited by PDE6 purified from bovine rod outer segments (ROS) indicate that the inhibitory gamma subunit of PDE6 may not be tightly bound to PDE6 catalytic sites.

  3. PDEdelta functions as a prenyl-binding protein interacting with multiple prenylated proteins in retinal rods.

Mouse (Murine) phosphodiesterase 6D, CGMP-Specific, Rod, delta (PDE6D) interaction partners

  1. It postulates a three-step mechanism regulating ciliary localization of INPP5E, consisting of farnesylation- and PDE6delta-mediated targeting, INPP5E-PDE6delta complex diffusion into the cilium with transfer to the IFT system, and retention inside cilia.

  2. the affinity to PDE6delta and the release by Arl2/3 in addition to a retention signal are the determinants for cargo sorting and enrichment at its destination.

  3. Knockout of Unc119 partially reversed the transport defect of GRK1 in cone photoreceptors caused by deletion of Pde6d.

  4. absence of PrBP/delta in retina impairs transport of prenylated proteins, particularly rhodopsin kinase 1 and cone PDE, to rod and cone outer segments

phosphodiesterase 6D, CGMP-Specific, Rod, delta (PDE6D) profil antigène

Profil protéine

Acts as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude and does so by decreasing the nucleotide dissociation rate. Stabilizes Arl3-GTP by decreasing the nucleotide dissociation (By similarity).

Gene names and symbols associated with PDE6D

  • phosphodiesterase 6D (Pde6d) anticorps
  • phosphodiesterase 6D (PDE6D) anticorps
  • phosphodiesterase 6D, cGMP-specific, rod, delta (pde6d) anticorps
  • phosphodiesterase 6D, cGMP-specific, rod, delta (Pde6d) anticorps
  • AI841218 anticorps
  • PDE6D anticorps
  • PDED anticorps
  • PrBP/delta anticorps
  • zgc:92605 anticorps

Protein level used designations for PDE6D

retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta , phosphodiesterase 6D, cGMP-specific, rod, delta , Retinal rod rhodopsin-sensitive cGMP 3,5-cyclic phosphodiesterase subunit delta , phosphodiesterase 6D , GMP-PDE delta , protein p17 , cGMP-phosphodiesterase delta subunit , pde6D gene for cGMP-phosphodiesterase delta subunit

GENE ID SPECIES
363272 Rattus norvegicus
424932 Gallus gallus
436981 Danio rerio
738319 Pan troglodytes
100286589 Salmo salar
100344476 Oryctolagus cuniculus
5147 Homo sapiens
281976 Bos taurus
403781 Canis lupus familiaris
18582 Mus musculus
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