phosphofructokinase, Platelet Protéines (PFKP)

The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11). De plus, nous expédions PFKP Anticorps (127) et PFKP Kits (41) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
PFKP 5214 Q01813
PFKP 56421 Q9WUA3
PFKP 60416 P47860
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Top PFKP Protéines sur anticorps-enligne.fr

Showing 10 out of 11 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 70 Days
$13,984.89
Détails
Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 70 Days
$13,984.89
Détails
Escherichia coli (E. coli) Humain His tag,T7 tag 100 μg Connectez-vous pour afficher 15 to 18 Days
$672.00
Détails
Human Cells Humain His tag   50 μg Connectez-vous pour afficher 4 Days
$385.00
Détails
Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$414.29
Détails
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Connectez-vous pour afficher Disponible
$547.80
Détails
Escherichia coli (E. coli) Humain Inconjugué SDS-PAGE analysis of Human PFKP Protein. 100 μg Connectez-vous pour afficher 11 to 18 Days
$625.39
Détails
Levure Rat His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$4,313.83
Détails
Escherichia coli (E. coli) Souris T7 tag,His tag 100 μg Connectez-vous pour afficher 15 to 18 Days
$704.00
Détails
Escherichia coli (E. coli) Rat T7 tag,His tag 100 μg Connectez-vous pour afficher 15 to 18 Days
$733.00
Détails

PFKP Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , , , ,
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Mouse (Murine) ,
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Rat (Rattus) ,
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Plus protéines pour phosphofructokinase, Platelet (PFKP) partenaires d'interaction

Human phosphofructokinase, Platelet (PFKP) interaction partners

  1. Snail functions as a metabolic switch between aerobic glycolysis and pentose phosphate pathway by repressing PFKP, a cancer-specific PFK-1, allowing cancer cell survival under metabolic stress.

  2. Here the authors show that PFK1 (Montrer PFKM Protéines) platelet isoform is upregulated in Glioblastoma and is required for tumor growth mechanistically, such upregulation is due to an increased stability induced by AKT (Montrer AKT1 Protéines) activation via phosphorylation on residue S386.

  3. Data indicate that platelet isoform of phosphofructokinase (PFKP) not only is required for metabolic reprogramming and maintaining cell proliferation, but also may be a valid target for anti-renal cancer pharmaceutical agents.

  4. The crystallized PFKP is permanently activated by a deletion of the 22 C-terminal residues.

  5. Anti-human protein S antibody induces tissue factor expression through a direct interaction with PFKP and ERK1/2 activation in coronary artery endothelial cells.

  6. expression of TARDBP (Montrer TARDBP Protéines) is significantly elevated in HCC (Montrer FAM126A Protéines) and it regulates the expression of PFKP, the rate-limiting enzyme for glycolysis, through negative regulation of microRNA 520s (miR (Montrer MLXIP Protéines)-520s).

  7. KLF4 (Montrer KLF4 Protéines) plays a role in maintenance of high glycolytic metabolism by transcriptional activation of the PFKP gene in breast cancer cells.

  8. PFKP was identified using a trifunctional phenyl sulfonate probe.

  9. Two phosphofructokinase (PFK) chimeras were constructed by exchanging the N- and C-terminal halves of the mammalian M- and C-type isozymes.

  10. PFKP polymorphisms play no apparent role in the development of common forms of obesity in the Danish population.

Profil protéine PFKP

Profil protéine

The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11). PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM\; MIM 610681) and liver (PFKL\; MIM 171860) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora (1981)

Gene names and symbols associated with PFKP

  • phosphofructokinase, platelet (pfkp)
  • phosphofructokinase, platelet (PFKP)
  • phosphofructokinase, platelet S homeolog (pfkp.S)
  • ATP-dependent 6-phosphofructokinase, platelet type (LOC100549777)
  • phosphofructokinase, platelet (Pfkp)
  • 1200015H23Rik Protéine
  • 9330125N24Rik Protéine
  • pfk Protéine
  • PFK-C Protéine
  • PFKF Protéine
  • PFKM Protéine
  • PFKP Protéine

Protein level used designations for PFKP

phosphofructokinase, platelet , 6-phosphofructokinase type C , PFK-C , phosphofructo-1-kinase isozyme C , phosphofructokinase 1 , phosphohexokinase , 6-phosphofructokinase, platelet type , Phosphofructokinase, platelet type , ATP:D-fructose 6-phosphate 1-phosphotransferase , 6-phosphofructo-1-kinase, C-type , phosphofructokinase C isozyme , phosphofructokinase, muscle

GENE ID SPECIES
394825 Xenopus (Silurana) tropicalis
450266 Pan troglodytes
100022041 Monodelphis domestica
100037146 Xenopus laevis
100070818 Equus caballus
100173619 Pongo abelii
100229947 Taeniopygia guttata
100549777 Meleagris gallopavo
100561110 Anolis carolinensis
100601116 Nomascus leucogenys
5214 Homo sapiens
56421 Mus musculus
60416 Rattus norvegicus
100009526 Oryctolagus cuniculus
100722738 Cavia porcellus
100521394 Sus scrofa
478019 Canis lupus familiaris
507119 Bos taurus
428411 Gallus gallus
101108592 Ovis aries
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