rho GTPase Activating Protein 44 Protéines (ARHGAP44)

GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. De plus, nous expédions rho GTPase Activating Protein 44 Anticorps (31) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
ARHGAP44 9912 Q17R89
ARHGAP44 216831 Q5SSM3
ARHGAP44    
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Showing 3 out of 3 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 70 Days
$13,984.89
Détails
Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 70 Days
$13,984.89
Détails
Escherichia coli (E. coli) Humain Inconjugué   5 applications Connectez-vous pour afficher 1 to 2 Days
$318.85
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ARHGAP44 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human ,

Mouse (Murine) ,

Rat (Rattus)

Plus protéines pour rho GTPase Activating Protein 44 (ARHGAP44) partenaires d'interaction

Human rho GTPase Activating Protein 44 (ARHGAP44) interaction partners

  1. Rho GTPase activating protein 44 (ARHGAP44) expression is lower in lung carcinoma compared with normal tissues. The GTP (Montrer AK3 Protéines) hydrolysis activity on cell division cycle 42 (Cdc42) and the expression level of ARHGAP44 are negatively correlated with cell migration and invasion.

  2. RICH2 is implicated in viremic control of HIV-1 in black South African individuals.

  3. Besides the already known chromosome 6 associations, the analysis of low-frequency single nucleotide polymorphisms brought up a new association in the RICH2 gene for progression to AIDS.

  4. Knocking down expression of RICH 2 causes loss of the apical actin network and apical microvilli, an increase in actin bundles at the basal surface, and a reduction in cell height. (RICH 2 protein)

  5. Demonstrates that the (Montrer ARHGAP1 Protéines) RhoGAP domains of RICH-1 and RICH-2 can catalyze GT (Montrer AK3 Protéines)P hydrolysis of both Rac1 and Cdc4 (Montrer CDC42 Protéines)2, but not of Rho (Montrer RHOA Protéines)A.

Mouse (Murine) rho GTPase Activating Protein 44 (ARHGAP44) interaction partners

  1. RICH2 knockout animals display a selective and highly significant fear of novel objects and increased stereotypic behavior as well as impairment of motor learning.

  2. These results suggested that Rich2 controls dendritic spine morphogenesis and function via inhibition of Rac1.

  3. Knock-down of Rich2 or disruption of Rich2-Shank3 complex, inhibits dendritic spine enlargement.

  4. Shows that the RhoGAP (Montrer ARHGAP1 Protéines) domain of the human RICH2 ortholog can catalyze GTP (Montrer AK3 Protéines) hydrolysis of both Rac1 and Cdc42 (Montrer CDC42 Protéines), but not of RhoA (Montrer RHOA Protéines).

Profil protéine rho GTPase Activating Protein 44 (ARHGAP44)

Profil protéine

GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Acts as a GTPase activitor in vitro for CDC42 and RAC1.

Gene names and symbols associated with ARHGAP44

  • Rho GTPase activating protein 44 (ARHGAP44)
  • si:ch211-114m9.1 (si:ch211-114m9.1)
  • Rho GTPase activating protein 44 (Arhgap44)
  • 6330543G20 Protéine
  • AI840762 Protéine
  • arhgap44 Protéine
  • AU040829 Protéine
  • AW493732 Protéine
  • NPC-A-10 Protéine
  • Rich2 Protéine

Protein level used designations for ARHGAP44

Rho-type GTPase-activating protein RICH2 , Rho GTPase activating protein 44 , RICH-2 , RhoGAP interacting with CIP4 homologs protein 2 , rho GTPase-activating protein 44 , rho GTPase-activating protein RICH2 , Rho GTPase-activating protein RICH2

GENE ID SPECIES
509257 Bos taurus
427797 Gallus gallus
455062 Pan troglodytes
567298 Danio rerio
718174 Macaca mulatta
100073101 Equus caballus
100415708 Callithrix jacchus
100585822 Nomascus leucogenys
9912 Homo sapiens
216831 Mus musculus
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