rho Guanine Nucleotide Exchange Factor (GEF) 15 Protéines (ARHGEF15)

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein-coupled receptors. De plus, nous expédions rho Guanine Nucleotide Exchange Factor (GEF) 15 Anticorps (6) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
Rat ARHGEF15 ARHGEF15 287418  
ARHGEF15 22899 O94989
ARHGEF15 442801 Q5FWH6
Comment commander chez anticorps-enligne
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Commandez enligne
  • orders@anticorps-enligne.fr

Top rho Guanine Nucleotide Exchange Factor (GEF) 15 Protéines sur anticorps-enligne.fr

Showing 3 out of 3 products:

Catalogue No. Origin Source Conjugué Images Quantité Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 70 Days
$13,741.67
Détails
Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 70 Days
$13,741.67
Détails
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg 11 Days
$888.80
Détails

ARHGEF15 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human ,
,
Mouse (Murine)

Plus protéines pour rho Guanine Nucleotide Exchange Factor (GEF) 15 (ARHGEF15) partenaires d'interaction

Human rho Guanine Nucleotide Exchange Factor (GEF) 15 (ARHGEF15) interaction partners

  1. pathological elevation of Ephexin5 expression critically drives Abeta-induced memory impairment

  2. upregulation of ARHGEF15 contributes to the development of aggressive PDAC by increasing the growth and motility of the pancreatic cancer cells, thereby worsening the prognosis of these patients.

  3. Arhgef15 acts as an endothelial cell-specific GEF to mediate VEGF-induced Cdc42 activation and potentiate RhoJ inactivation, thereby promoting actin polymerization and cell motility.

  4. This paper presents functional studies determined in rat, mouse, and human tissues and cell lines.

Mouse (Murine) rho Guanine Nucleotide Exchange Factor (GEF) 15 (ARHGEF15) interaction partners

  1. pathological elevation of Ephexin5 expression critically drives Abeta-induced memory impairment

  2. The data of this study support a model in which Ephexin5 serves a dual role in spinogenesis, acting both as a brake on overall spine outgrowth and as a necessary component in the site-specific formation of new spines

  3. Study identified a RhoA guanine nucleotide exchange factor, Ephexin5, which negatively regulates excitatory synapse development until EphrinB binding to the EphB receptor triggers Ephexin5 phosphorylation, ubiquitination, and degradation.[Ephexin5]

Profil protéine rho Guanine Nucleotide Exchange Factor (GEF) 15 (ARHGEF15)

Profil protéine

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein-coupled receptors. This gene encodes a protein that functions as a specific guanine nucleotide exchange factor for RhoA. It also interacts with ephrin A4 in vascular smooth muscle cells. Two alternatively spliced transcripts variants that encode the same protein have been found for this gene.

Gene names and symbols associated with ARHGEF15

  • Rho guanine nucleotide exchange factor 15 (Arhgef15)
  • Rho guanine nucleotide exchange factor 15 (ARHGEF15)
  • Rho guanine nucleotide exchange factor (GEF) 15 (Arhgef15)
  • ARGEF15 Protéine
  • ARHGEF15 Protéine
  • D130071N09 Protéine
  • D530030K12Rik Protéine
  • E5 Protéine
  • Ephexin5 Protéine
  • Vsm-RhoGEF Protéine

Protein level used designations for ARHGEF15

ephexin-5 , rho guanine nucleotide exchange factor 15 , Rho guanine nucleotide exchange factor (GEF) 15 , Rho guanine exchange factor 15 , rho guanine nucleotide exchange factor 15-like , Rho GEF 15 , Rho guanine exchange factor (GEF) 15

GENE ID SPECIES
287418 Rattus norvegicus
454465 Pan troglodytes
489492 Canis lupus familiaris
512021 Bos taurus
721968 Macaca mulatta
100350440 Oryctolagus cuniculus
100404756 Callithrix jacchus
100589438 Nomascus leucogenys
100627972 Sus scrofa
22899 Homo sapiens
442801 Mus musculus
Fournisseurs de qualité sélectionnés pour rho Guanine Nucleotide Exchange Factor (GEF) 15 Protéines (ARHGEF15)
Avez-vous cherché autre chose?