tRNA Aspartic Acid Methyltransferase 1 (TRDMT1) Kits ELISA

TRDMT1 encodes a protein responsible for the methylation of aspartic acid transfer RNA, specifically at the cytosine-38 residue in the anticodon loop. De plus, nous expédions tRNA Aspartic Acid Methyltransferase 1 Anticorps (145) et tRNA Aspartic Acid Methyltransferase 1 Protéines (10) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
TRDMT1 1787 O14717
TRDMT1 13434 O55055
TRDMT1 291324 Q4G073
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Top tRNA Aspartic Acid Methyltransferase 1 Kits ELISA sur anticorps-enligne.fr

Showing 4 out of 9 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Fournisseur Livraison Prix Détails
Humain 46.875 pg/mL 78.125-5000 pg/mL Typical standard curve 96 Tests Connectez-vous pour afficher 12 to 14 Days
$630.00
Détails
Souris < 0.094 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Connectez-vous pour afficher 11 to 18 Days
$810.17
Détails
Rat < 0.094 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Connectez-vous pour afficher 11 to 18 Days
$810.17
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Boeuf (Vache)
  96 Tests Connectez-vous pour afficher 15 to 18 Days
$1,029.60
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Plus Kits ELISA pour tRNA Aspartic Acid Methyltransferase 1 partenaires d'interaction

Human tRNA Aspartic Acid Methyltransferase 1 (TRDMT1) interaction partners

  1. Data suggest that, upon HIV-1 infection, DNMT2 is re-localized from the nucleus to cytoplasmic stress granules where DNMT2 methylates HIV-1 messenger RNA; this methylation increases the stability of the HIV-1 RNA genome and up-regulates virus replication; thus, DNMT2 appears to facilitate HIV-1 infection.

  2. The strong effect of some of the somatic cancer mutations on DNMT2 activity suggests that these mutations have a functional role in tumorigenesis.

  3. DNMT1 (Montrer DNMT1 Kits ELISA), DNMT2 and DNMT3A (Montrer DNMT3A Kits ELISA) may play important roles in gastric cancer carcinogenesis.

  4. Mapped is the tRNA binding site of DNMT2 by systematically mutating surface-exposed lysine and arginine residues to alanine and studying the tRNA methylation activity and binding of the corresponding variants.

  5. the role of Dnmt2 in stress granules could represent a primitive cellular defense mechanism against viral infection.

  6. The expression of DNMT1 (Montrer DNMT1 Kits ELISA), DNMT2, DNMT3A (Montrer DNMT3A Kits ELISA) and DNMT3B (Montrer DNMT3B Kits ELISA) in pediatric acute lymphoblastic leukemia patients, was investigated.

  7. Hepatitis B virus-induced overexpression of DNMTs leads to viral DNA methylation and decreased viral gene expression and also leads to methylation of host CpG islands.

  8. cDNA microarray analysis identified several genes involved in DNA methylation, such as DNMT2 and DNMT3a (Montrer DNMT3A Kits ELISA) that were more highly expressed in LNCaP-r (an androgen sensitive prostate cancer cell line).

  9. genetic and biochemical approach revealed that DNMT2 did not methylate DNA but instead methylated aspartic acid transfer RNA (tRNA(Asp (Montrer ASIP Kits ELISA))) and that DNMT2 specifically methylated cytosine 38 in the anticodon loop

  10. An association study of 45 folate-related genes in spina bifida: Involvement of tRNA aspartic acid methyltransferase 1 (TRDMT1)

Mouse (Murine) tRNA Aspartic Acid Methyltransferase 1 (TRDMT1) interaction partners

  1. Dnmt2 may promote lifespan in the control conditions and survival during stress conditions in mouse fibroblasts.

  2. Dnmt2 plays an unexpected role for regulation of cardiac growth by modulating activity of the P-TEFb (Montrer CCNT1 Kits ELISA) complex.

  3. Treatment of aged mice and their derived macrophages with methyltransferase inhibitor (2)-epigallocatechin-3-gallate (EGCG) or specific DNA methyltransferase 2 (DNMT2) siRNA restored the expression of Atg5 (Montrer ATG5 Kits ELISA) and LC3 (Montrer MAP1LC3A Kits ELISA) in vivo and in vitro.

  4. Dnmt2 plays an important role in haematopoiesis and define a novel function of C38 tRNA methylation in the discrimination of near-cognate codons, thereby ensuring accurate polypeptide synthesis.

  5. these findings uncover a novel function of Dnmt2 in RNA-mediated epigenetic heredity

  6. Dnmt2-dependent methylomes lack defined DNA methylation patterns.

  7. Steady-state levels of unmethylated tRNAs were substantially reduced, and loss of Dnmt2 and NSun2 was further associated with reduced rates of overall protein synthesis.

  8. the role of Dnmt2 in stress granules could represent a primitive cellular defense mechanism against viral infection.

tRNA Aspartic Acid Methyltransferase 1 (TRDMT1) profil antigène

Antigen Summary

This gene encodes a protein responsible for the methylation of aspartic acid transfer RNA, specifically at the cytosine-38 residue in the anticodon loop. This enzyme also possesses residual DNA-(cytosine-C5) methyltransferase activity. While similar in sequence and structure to DNA cytosine methyltransferases, this gene is distinct and highly conserved in its function among taxa.

Gene names and symbols associated with TRDMT1

  • tRNA aspartic acid methyltransferase 1 (trdmt1) anticorps
  • tRNA aspartic acid methyltransferase 1 (TRDMT1) anticorps
  • tRNA aspartic acid methyltransferase 1 (Trdmt1) anticorps
  • tRNA aspartic acid methyltransferase 1 L homeolog (trdmt1.L) anticorps
  • DMNT2 anticorps
  • dnmt2 anticorps
  • MGC89267 anticorps
  • MHSAIIP anticorps
  • PUMET anticorps
  • RNMT1 anticorps
  • Rnmt2 anticorps

Protein level used designations for TRDMT1

tRNA aspartic acid methyltransferase 1 , DNA (cytosine-5)-methyltransferase-like protein 2 , DNA MTase homolog HsaIIP , DNA methyltransferase-2 , tRNA (cytosine(38)-C(5))-methyltransferase , tRNA (cytosine-5-)-methyltransferase , DNA MTase homolog MmuIIP , DNA methyltransferase 2 , DNA methyltransferase homolog MmuIIP , m.MmuIIP , met-2 , DNA (cytosine-5-)-methyltransferase 2

GENE ID SPECIES
448379 Xenopus (Silurana) tropicalis
100230580 Taeniopygia guttata
100346643 Oryctolagus cuniculus
100407322 Callithrix jacchus
100463906 Ailuropoda melanoleuca
100605724 Nomascus leucogenys
1787 Homo sapiens
13434 Mus musculus
379360 Xenopus laevis
420520 Gallus gallus
487116 Canis lupus familiaris
100302362 Sus scrofa
353353 Bos taurus
291324 Rattus norvegicus
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