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Human Polyclonal Angiotensin II Type 2 Receptor Primary Antibody pour ELISA, ICC - ABIN4278731
Hafko, Villapol, Nostramo, Symes, Sabban, Inagami, Saavedra: Commercially available angiotensin II At₂ receptor antibodies are nonspecific. dans PLoS ONE 2013
Show all 10 Pubmed References
The genotypes of REN (Montrer REN Anticorps), AT1R (Montrer AGTR1 Anticorps) and AT2R were not associated with the development of preeclampsia in South African Black women.
These data indicate that Ang II (Montrer AGT Anticorps)-AT2R regulates human bone marrow MSC (Montrer MSC Anticorps) migration by signaling through the FAK (Montrer PTK2 Anticorps) and RhoA (Montrer RHOA Anticorps)/Cdc42 (Montrer CDC42 Anticorps) pathways.
Low levels of AT2R is associated with angiogenesis in bladder cancer.
angiotensin II type 2 receptor activation in inguinal adipocytes opposes norepinephrine-induced uncoupling protein-1 (UCP1 (Montrer UCP1 Anticorps)) production and aspects of cellular respiration
loss of AT2 R is associated with podocyte loss/dysfunction and is mediated, at least in part, via augmented ectopic hedgehog interacting protein (Montrer HHIP Anticorps) expression in podocytes
In this genomewide association study, we found that variants at the EBF1 (Montrer EBF1 Anticorps), EEFSEC (Montrer EEFSEC Anticorps), AGTR2, WNT4 (Montrer WNT4 Anticorps), ADCY5 (Montrer ADCY5 Anticorps), and RAP2C (Montrer RAP2C Anticorps) loci were associated with gestational duration and variants at the EBF1 (Montrer EBF1 Anticorps), EEFSEC (Montrer EEFSEC Anticorps), and AGTR2 loci with preterm birth.
crystal structures of human AT2R bound to an AT2R-selective ligand and to an AT1R (Montrer AGTR1 Anticorps)/AT2R dual ligand, capturing the receptor in an active-like conformation
Suggest a gender-specific association between the AT2R -1332 A/G polymorphism and the occurrence of carotid plaque and the history of cerebrovascular insult in advanced carotid atherosclerosis.
peripheral and central arterial pressures and pulse wave augmentation indexes (AIx(P), AIx(C1), AIx(C2)), pulse wave velocity (PWV), daily urinary sodium excretion were measured and did genetic studies of AGTR1 (Montrer AGTR1 Anticorps) A1166C and AGTR2 G1675A polymorphisms.
Significant overrepresentation of AT2R-1332 AA genotype in female multiple sclerosis patients was found, compared to female controls.
crosstalk between AT2 receptor stimulation and PPARgamma (Montrer PPARG Anticorps) activation could contribute to attenuation of vascular intimal proliferation
Deletion of AT2 receptor reduced SHP-1 (Montrer PTPN6 Anticorps) activity and restored VEGF (Montrer VEGFA Anticorps) actions, leading to an increased blood flow reperfusion after ischemia in diabetes mellitus.
Our current results reinforce the notion that the AT2R has a physiological role in the conservation of insulin (Montrer INS Anticorps) action
Ultra-high doses did not influence the ACE2 (Montrer ACE2 Anticorps)/AT2R/Mas (Montrer MAS1 Anticorps) axis and promoted renal injury with increased renal ERK1/2 activation and exaggerated fibronectin (Montrer FN1 Anticorps) expression in db/db (Montrer LEPR Anticorps) mice. Our study demonstrates dose-related effects of candesartan in diabetic nephropathy: intermediate-high dose candesartan is renoprotective, whereas ultra-high dose candesartan induces renal damage.
This study aimed to define whether sex chromosome complement (SCC (Montrer CYP11A1 Anticorps)) may differentially modulate sex differences in relative gene expression of basal Agtr1a (Montrer AGTR1 Anticorps), Agtr2, and Mas1 (Montrer MAS1 Anticorps) receptors at fore/hindbrain nuclei and at medulla/cortical kidney.
AT2R-dependent interleukin-17 (Montrer IL17A Anticorps) production by T lymphocyte is necessary for collateral artery growth.
Altered expression of AT1 and AT2 receptors with aging may induce mitochondrial dysfunction, the main risk factor for neurodegeneration.
AT2R inhibits adipogenic differentiation in mesenchymal stem cells. Moreover, this inhibitory effect is associated with Wnt10b (Montrer WNT10B Anticorps)/beta-catenin (Montrer CTNNB1 Anticorps) signaling.
These results suggest that nerve growth factor-mediated neurite outgrowth is suppressed by AT2 receptor signaling via the nitric oxide-cyclic GMP (Montrer NT5C2 Anticorps)-PKG (Montrer PRKG1 Anticorps) pathway.
Luminal ANG II is internalized as a complex with AT1R/AT2R heterodimers to target endoplasmic reticulum in LLC-PK1 cells, where it might trigger intracellular calcium responses.
AT1 (Montrer AGTR1 Anticorps) and AT2 receptors heterodimerize and are involved in the angiotensin II effect on SERCA (Montrer ATP2A3 Anticorps) in proximal kidney tubules.
AT2 receptors are positively coupled to the proliferative response of vascular smooth muscle cells to angiotensin II.
Glomerular eNOS (Montrer NOS3 Anticorps) gene expression was studied during postnatal maturation and AT1 receptor (Montrer AGTRAP Anticorps) inhibition.
Data suggest that AGTR2 (and angiotensin-converting enzyme (Montrer ACE Anticorps)) mRNA levels are transiently up-regulated in ovarian theca cells during preovulatory period.
data suggest that G alpha(i3), Shc (Montrer SHC1 Anticorps), Grb2 (Montrer GRB2 Anticorps), Ras, and Raf-1 (Montrer RAF1 Anticorps) link Src (Montrer SRC Anticorps) to activation of MAPK (Montrer MAPK1 Anticorps) and to the AT(2)-dependent increase in eNOS (Montrer NOS3 Anticorps) expression in PAECs
Abundance of AGTR2 mRNA in granulosa cells was higher in healthy compared with atretic follicles, whereas in theca cells, it did not change
The protein encoded by this gene belongs to the G-protein coupled receptor 1 family, and functions as a receptor for angiotensin II. It is an intergral membrane protein that is highly expressed in fetus, but scantily in adult tissues, except brain, adrenal medulla, and atretic ovary. This receptor has been shown to mediate programmed cell death and this apoptotic function may play an important role in developmental biology and pathophysiology. Mutations in this gene are been associated with X-linked mental retardation.
angiotensin II type-2 receptor
, type-2 angiotensin II receptor
, AT2 receptor
, angiotensin II type 2 receptor
, angiotensin receptor 2
, angiotensin II receptor type 2
, angiotensin II receptor, type 2
, angiotensin type II receptor
, Type-2 angiotensin II receptor
, angiotensin II subtype 2 receptor, AT2