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anti-Human AIM2 Anticorps:
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Human Polyclonal AIM2 Primary Antibody pour IF, WB - ABIN522906
Fernandes-Alnemri, Yu, Datta, Wu, Alnemri: AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA. dans Nature 2009
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Human Monoclonal AIM2 Primary Antibody pour WB - ABIN1882191
Chen, Ou-Yang, Hung, Liu, Wang, Wang, Hou, Hortobagyi, Hung: AIM2 suppresses human breast cancer cell proliferation in vitro and mammary tumor growth in a mouse model. dans Molecular cancer therapeutics 2006
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Human Monoclonal AIM2 Primary Antibody pour WB - ABIN1882206
DeYoung, Ray, Su, Anzick, Johnstone, Trapani, Meltzer, Trent: Cloning a novel member of the human interferon-inducible gene family associated with control of tumorigenicity in a model of human melanoma. dans Oncogene 1997
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Human Monoclonal AIM2 Primary Antibody pour ICC, WB - ABIN1169341
Cresswell, Clarke, Jackson, Darcy, Trapani, Johnstone: Biochemical and growth regulatory activities of the HIN-200 family member and putative tumor suppressor protein, AIM2. dans Biochemical and biophysical research communications 2004
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Human Polyclonal AIM2 Primary Antibody pour ELISA, IHC - ABIN4278860
Choubey, Duan, Dickerson, Ponomareva, Panchanathan, Shen, Srivastava: Interferon-inducible p200-family proteins as novel sensors of cytoplasmic DNA: role in inflammation and autoimmunity. dans Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2010
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Human Polyclonal AIM2 Primary Antibody pour IP, WB - ABIN948806
Adamczak, de Rivero Vaccari, Dale, Brand, Nonner, Bullock, Dahl, Dietrich, Keane: Pyroptotic neuronal cell death mediated by the AIM2 inflammasome. dans Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2014
Mouse (Murine) Polyclonal AIM2 Primary Antibody pour ELISA, WB - ABIN4252907
Wenzel, Wunderlich, Besch, Poeck, Willms, Schwantes, Kremer, Sutter, Endres, Schmidt, Rothenfusser: Cytosolic DNA triggers mitochondrial apoptosis via DNA damage signaling proteins independently of AIM2 and RNA polymerase III. dans Journal of immunology (Baltimore, Md. : 1950) 2011
These results provide evidence for the role of AIM2 in the progression of cSCC (Montrer CYP11A1 Anticorps) and identify AIM2 inflammasome function as a potential therapeutic target in these invasive and metastatic tumors.
RSAD2 and AIM2 Modulate Coxsackievirus A16 and Enterovirus A71 Replication in Neuronal Cells in Different Ways That May Be Associated with Their 5' Nontranslated Regions.
AIM2 inflammasome expression and activation is increased early during the course of acute pancreatitis, and suggests that AIM2 activation may affect systemic inflammation and organ failure in these patients
Overexpression of AIM2 in hepatocellular carcinoma (HCC (Montrer FAM126A Anticorps)) cells suppressed mammalian target of rapamycin (mTOR (Montrer FRAP1 Anticorps))-S6K1 (Montrer RPS6KB1 Anticorps) pathway and further inhibited proliferation of HCC (Montrer FAM126A Anticorps) cells.
AIM2 is an important component of the inflammasome in tegumentary leishmaniasis (TL) patients and is directly associated with the severity of lesions.
TRIM11 suppresses AIM2 inflammasome by degrading AIM2 via p62-dependent selective autophagy.
AIM2 contributes to the maintenance of intestinal integrity via Akt (Montrer AKT1 Anticorps) and protects against Salmonella mucosal infection.
study identifies the AIM2 inflammasome and cGAS/IFI16 (Montrer IFI16 Anticorps)-STING-type I IFN pathway as a novel mechanism for host innate immunity to the ALVAC vaccine vector.
Study conclude that functional AIM2 is preferentially expressed in adult human CD27 (Montrer CD27 Anticorps)+ B-cells, but is absent in cord blood mononuclear cells.
results suggest that the function of AIM2 is focused on the innate immune response, and AIM2 is a detrimental host factor for influenza-induced lung injury and mortality.
These data provide evidence that the inflammasome components ASC (Montrer STS Anticorps), NLRP3 (Montrer NLRP3 Anticorps) and AIM2 play a role in regulating macrophage adhesion and activation in response to surface nanotopography and chemistry.
Thus, we demonstrated that AIM2 could promote the progression of atherosclerotic plaque by increasing migration in VSMCs.
AIM2 cytosolic DNA sensor may conjugate competitively with cytosolic Mycobacterium bovis DNA to restrict Mycobacterium bovis induced STING-TBK1 (Montrer TBK1 Anticorps)-dependent autophagy activation and IFN-beta (Montrer IFNB1 Anticorps) secretion.
this study shows that aim2-like receptors are dispensable for the type I interferon (Montrer IFNA Anticorps) response to transfected DNA ligands, DNA virus infection, and lentivirus infection
These results show for the first time that AIM2 plays an important anti-inflammatory, yet inflammasome-independent function in cardiomyocytes
These results demonstrate a central role for the AIM2 inflammasome in preventing dysbiosis and intestinal inflammation through regulation of the IL-18 (Montrer IL18 Anticorps)/IL-22BP (Montrer IL22RA2 Anticorps)/IL-22 (Montrer IL22 Anticorps) and STAT3 (Montrer STAT3 Anticorps) pathway
AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2.
absent in melanoma 2
, interferon-inducible protein AIM2-like
, interferon-inducible protein AIM2
, interferon-inducible protein 210
, interferon-inducible protein p210