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Cow (Bovine) Polyclonal CNPY3 Primary Antibody pour IHC, WB - ABIN2775784
Clark, Edwards, Peterson, Clifton, Thompson, Sasaki, Suzuki, Kikuchi, Watabe, Kawakami, Sugano, Elgar, Johnson: Fugu ESTs: new resources for transcription analysis and genome annotation. dans Genome research 2003
Show all 3 Pubmed References
Human Polyclonal CNPY3 Primary Antibody pour IHC (p) - ABIN4239480
Hart, Tapping: Cell surface trafficking of TLR1 is differentially regulated by the chaperones PRAT4A and PRAT4B. dans The Journal of biological chemistry 2012
association with PRAT4A is required for ligand-induced trafficking of TLR9 to endolysosomes
Cell surface expression of TLR5 is dependent on PRAT4A and restricted to neutrophils, classical monocytes and specific DC subsets.
Data suggest that CNPY3 interacts with the ATP-sensitive conformation of gp96 to promote substrate loading. Our study has thus established CNPY3 as a TLR-specific cochaperone for gp96.
PRAT4A is a novel protein associated with toll-like receptor (TLR) 4 that regulates cell surface expression of receptor complex TLR4/MD-2.
PRAT4A regulates the subcellular distribution and response of multiple toll-like recaptors and is required for both innate and adaptive immune responses
single base mutant associates preferentially with TLR9, and differentially interacts with TLR2, 4 and 9
The data suggest that CNPY3 performs essential roles in brain function, in addition to known Toll-like receptor-dependent immune responses.
a mechanism for the differential trafficking of TLR1 I602S variants, and highlight the distinct roles for PRAT4A and PRAT4B in the regulation of TLR1 surface expression.
PRAT4A is associated with the immature form of TLR4 (MIM 603030) and regulates its cell surface expression (Wakabayashi et al., 2006
canopy 3 homolog (zebrafish)
, trinucleotide repeat containing 5
, Protein canopy homolog 3
, canopy 3 homolog
, protein canopy homolog 3
, protein canopy homolog 3-like
, trinucleotide repeat-containing gene 5 protein
, protein associated with Tlr4
, protein associated with toll-like receptor 4
, CAG repeat containing
, CTG repeat protein 4a
, expanded repeat domain, CAG/CTG 5
, expanded repeat-domain protein CAG/CTG 5
, protein associated with TLR4
, protein associated with Toll-like receptor 4A
, canopy 3