Profil protéine

This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome.

Alternative names and synonyms associated with NOD2

• caspase recruitment domain 15 protein (TTHERM_01951320) anticorps
• nucleotide binding oligomerization domain containing 2 (NOD2) anticorps
• nucleotide-binding oligomerization domain containing 2 (Nod2) anticorps

• ACUG anticorps
• BLAU anticorps
• Card15 anticorps
• CD anticorps
• CLR16.3 anticorps
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• F830032C23Rik anticorps
• IBD1 anticorps
• Nlrc2 anticorps
• NOD2B anticorps
• PSORAS1 anticorps

Protein level used designations for NOD2

caspase recruitment domain 15 protein , NLR family, CARD domain containing 2 , NOD-like receptor C2 , caspase recruitment domain family, member 15 , caspase recruitment domain protein 15 , caspase recruitment domain-containing protein 15 , inflammatory bowel disease protein 1 , nucleotide-binding oligomerization domain 2 , nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 2 , nucleotide-binding oligomerization domain-containing protein 2