Profil protéine

This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm\; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with PYCARD

• PYD and CARD domain containing (PYCARD) anticorps
• PYD and CARD domain containing (Pycard) anticorps
• PYD and CARD domain containing (pycard) anticorps

• 9130417A21Rik anticorps
• Asc anticorps
• asc1 anticorps
• CARD5 anticorps
• masc anticorps
• Afficher tous les alias de synonymes
• TMS anticorps
• TMS-1 anticorps
• TMS1 anticorps
• TNS1 anticorps
• zAsc anticorps
• zgc:109874 anticorps

Protein level used designations for PYCARD

apoptosis-associated speck-like protein containing a CARD , caspase recruitment domain-containing protein 5 , target of methylation-induced silencing 1 , PYD and CARD domain-containing protein