-
S100A14 increases the motility of lung adenocarcinoma cells, and might be a diagnostic and prognostic serum biomarker and potential therapeutic target for lung adenocarcinoma.
-
S100A14 is expressed in a subset of lung adenocarcinoma, and its expression is related to certain clinicopathological parameters. Furthermore, S100A14 expression was strongly correlated with migration and invasion in lung adenocarcinoma cells.
-
Increased S100A15 expression and decreased DNA methylation of its gene promoter region were associated with high metastasis potential and poor outcome in lung adenocarcinoma.
-
results indicate that S100A14 may have a role in the induction of differentiation and inhibition of cell metastasis in gastric cancer.
-
We identified a two-gene signature including KCNN4 and S100A14 which was related to recurrence in optimally debulked serous ovarian carcinoma patients
-
Co-expression of S100A14 and S100A16 correlates with a poor prognosis in human breast cancer and promotes cancer cell invasion
-
The antimicrobial peptides psoriasin (S100A7) and koebnerisin (S100A15) suppress extracellular matrix production and proliferation of human fibroblasts
-
S100A14 is expressed in epithelial-like, but not in mesenchymal-like, triple-negative breast cancer cells in vitro.
-
Data show that the genetic variant 425G>A on the 5'-UTR of calcium-binding protein S100A14 was associated with reduced S100A14 expression in gastric cancer (GC) cells.
-
Data indicate that S100A14 has a crucial role in EOC progression, and its overexpression is associated with poor prognosis.
-
Data demonstrate that S100A14 is transcriptionally regulated by JunB and involved in esophageal squamous cell carcinoma cell differentiation.
-
S100A14 interacts with S100A16 and regulates its expression in human cancer cells.
-
Data show that S100A14 and HER2 are colocalized in plasma membrane of breast cancer tissue cells and breast cancer cell lines.
-
High S100A14 expression is associated with metastasis of hepatocellular carcinoma.
-
The solution structure of homodimeric S100A14 in the apo state solved by NMR
-
that S100A14 promotes cell motility and invasiveness by regulating the expression and function of MMP2 in a p53-dependent manner.
-
S100A14 provides a novel role in oral squamous cell carcinoma cell proliferation by inducing G1-arrest
-
S100A14 induces cell apoptosis is partially in a RAGE-dependent manner
-
S100A14 and S100A4 have roles in metastasis in colorectal cancer after surgery
-
Data constitute strong evidence in support of the notion that S100A14 might function as a cancer suppressor working in the P53 pathway and play a role in esophageal carcinogenesis.