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Human Polyclonal CAMKK1 Primary Antibody pour ICC, IF - ABIN446068
Hamada, Souda, Yoshimura, Sasaguri, Hatanaka, Tasaki, Yoshioka, Ohi, Yamada, Tsutsui, Umekita, Tanimoto: Anti-apoptotic effects of PCP4/PEP19 in human breast cancer cell lines: a novel oncotarget. dans Oncotarget 2014
Site-directed mutagenesis analysis revealed that Leu(358) in CaMKKbeta/Ile(322) in CaMKKalpha confer, at least in part, a distinct recognition of AMPK (Montrer PRKAA1 Anticorps) but not of CaMKIalpha (Montrer CAMK1 Anticorps).
CaMKK1 does not play a pivotal role in the calcium signaling cascade regulating adrenal aldosterone production.
CAMKK1 might contribute to the risk of lung cancer in Chinese populations.
CaMKIalpha (Montrer CAMK1 Anticorps) is a widely expressed protein kinase (Montrer CDK7 Anticorps), suggesting that Ca2 (Montrer CA2 Anticorps)+ is likely to be functionally important in the control of mitochondrial dynamics through regulation of Drp1 (Montrer CRMP1 Anticorps) phosphorylation in neurons and other cell types.[CaMKIalpha (Montrer CAMK1 Anticorps)]
Adiponectin activates AMP-activated protein kinase (Montrer PRKAA2 Anticorps) in muscle cells via APPL1 (Montrer APPL1 Anticorps)/LKB1 (Montrer STK11 Anticorps)-dependent and phospholipase C (Montrer PLC Anticorps)/Ca2+/Ca2 (Montrer CA2 Anticorps)+/calmodulin-dependent protein kinase (Montrer CDK7 Anticorps) kinase-dependent pathways
the CaMKK (Montrer CAMKK2 Anticorps)-CaMKIalpha (Montrer CAMK1 Anticorps) cascade is required for the axonal growth effect of Wnt5a (Montrer WNT5A Anticorps) during neuronal polarization.
Data (including data from knockout mice) suggest that up-regulation of Camkk1 and calcium signaling stimulates muscle growth via up-regulation of mTORC1 (mammalian target of rapamycin (Montrer FRAP1 Anticorps) complex 1) signaling and muscle protein biosynthesis.
caCaMKKalpha stimulates glucose uptake additively with insulin (Montrer INS Anticorps), and in insulin (Montrer INS Anticorps)-resistant muscle, and alters the phosphorylation of TBC1D1 (Montrer TBC1D1 Anticorps)/TBC1D4 (Montrer TBC1D4 Anticorps).
ERK (Montrer EPHB2 Anticorps) activation and neurite outgrowth in response to depolarization are mediated by CaMKK (Montrer CAMKK2 Anticorps) activation of CaMKI (Montrer CAMK1 Anticorps)
In muscles from wild-type mice CaMKKalpha increased in vivo deoxyglucose uptake and AMPKalpha1 (Montrer PRKAA1 Anticorps) and -alpha2 activities 2.5-fold.
Data show that CaMKK (Montrer CAMKK2 Anticorps) is the kinase responsible for alpha-lipoic acid induced AMP-activated protein kinase (Montrer PRKAA2 Anticorps) activation in C2C12 myotubes.
The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade. Three transcript variants encoding two distinct isoforms have been identified for this gene.
, camkk 1
, calcium/calmodulin-dependent protein kinase kinase 1
, calcium/calmodulin-dependent protein kinase kinase 1, alpha
, calcium/calmodulin-dependent protein kinase 1 alpha-like
, calcium/calmodulin-dependent protein kinase kinase 1-like
, CAMKK alpha protein
, caM-KK 1
, caM-KK alpha
, caM-kinase IV kinase
, caM-kinase kinase 1
, caM-kinase kinase alpha
, caMKK 1
, calcium/calmodulin-dependent protein kinase kinase alpha
, caMKK alpha
, calcium calmodulin dependent protein kinase kinase alpha
, alpha CaMKK