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Cyclin O (CCNO) (Internal Region) anticorps Primary Antibody

CCNO Reactivité: Humain, Souris, Rat ELISA, WB Hôte: Lapin Polyclonal
N° du produit ABIN1003415
$513.04
Plus shipping costs $45.00
100 μg
local_shipping Destination: Etats-Unis
Envoi sous 15 à 19 jours ouvrables
  • Antigène
    Épitope
    Internal Region
    Reactivité
    Humain, Souris, Rat
    Hôte
    Lapin
    Clonalité
    Polyclonal
    Conjugué
    Inconjugué
    Application
    ELISA, Western Blotting (WB)
    Blocking Peptide
    Blocking peptide for this product available: ABIN1003990
    Purification
    Affinity chromatography purified via peptide column.
    Immunogène
    UNG2 antibody was raised against a 13 amino acid peptide from near the center of human UNG2.
    Isotype
    IgG
  • Antigène
    Autre désignation
    Uracil-DNA Glycosylase 2 (UDG2) (CCNO Antibody Extrait)
    Sujet
    The human uracil-DNA glycosylase (UNG) gene encodes both mitochondrial (UNG1) and nuclear (UNG2) forms through differentially regulated promotes and alternative splicing. UNG2 is the major enzyme in the base excision repair pathway that removes uracil residues from DNA that arise through either misincorporation during replication or cytosine deamination . UNG2 can also be bound by the HIV-1 integrase and incorporated into the virion particle, suggesting that it is required to remove uracils from the viral genome. As the intrinsic antiviral protein APOBEC3G generates numerous uracils in the HIV genome during its replication, it may be that the UNG2 contributes to the APOBEC3G-mediated loss of infectivity by generating abasic sites in the viral genome. This UNG2 antibody will not cross-react with UNG1.
  • Indications d'application
    UNG2 antibody can be used for the detection of UNG2 by Western blot at 1 – 2 µg/ml. (Optimal dilution should be determined by user.) Antibody can also be used for ELISA and might be suited for other applications not tested so far.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Antibody is supplied in PBS containing 0.02% sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Antibody can be stored at 4 °C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 myl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap.
    Stock
    4 °C
    Date de péremption
    12 months
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