CCL20 anticorps

N° du produit ABIN1043784

Détail du produit anti-CCL20 anticorps

Antigène: CCL20 (Chemokine (C-C Motif) Ligand 20 (CCL20))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CCL20 est non-conjugé

Application: Western Blotting (WB)

Specificité: Anti-MIP-3alpha was purified from clarified mouse ascetic fluid by Protein A chromatography followed by extensive dialysis against the buffer stated above. This antibody is specific for human MIP-3alpha protein. A BLAST analysis was used to suggest cross-reactivity with MIP-3alpha from human sources based on 100% homology with the immunizing sequence. Cross-reactivity with MIP-3alpha from other sources has not been determined.

Attributs du produit: MIP-3alpha (also known as C-C motif chemokine 20, small-inducible cytokine A20, macrophage inflammatory protein 3 alpha, MIP-3-alpha, liver and activation-regulated chemokine, CC chemokine LARC and beta chemokine exodus-1) is a chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. MIP-3alpha inhibits proliferation of myeloid progenitors in colony formation assays and may be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. MIP-3alpha also possesses antibacterial activity against E.coli and S.aureus. MIP-3alpha is a secreted protein that is expressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels of expression are also seen in thymus, prostate, testis, small intestine and colon. C-terminal processed forms which lack 1, 3 or 6 amino acids are produced by proteolytic cleavage after secretion from peripheral blood monocytes.

Stérilité: Sterile filtered

Immunogène: Anti-MIP-3alpha (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with mature full length recombinant human MIP-3alpha produced in E.coli followed by hybridoma development.
Immunogen Type: RecombinantProtein

Clone: 3N2D9

Isotype: IgG1

Information d'application

Indications d'application: Anti-Human MIP-3α antibody has been tested for use in Western Blot. Specific conditions for reactivity should be optimized by the end user.

Commentaires:

Gene Name: CCL20

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.

Date de péremption: 12 months

Références pour anticorps anti-CCL20 (ABIN1043784)

Lisignoli, Manferdini, Codeluppi, Piacentini, Grassi, Cattini, Filardo, Facchini: "CCL20/CCR6 chemokine/receptor expression in bone tissue from osteoarthritis and rheumatoid arthritis patients: different response of osteoblasts in the two groups." dans: Journal of cellular physiology, Vol. 221, Issue 1, pp. 154-60, (2009) (PubMed).

Détails sur CCL20

Antigène: CCL20 (Chemokine (C-C Motif) Ligand 20 (CCL20))

Autre désignation: MIP-3alpha (CCL20 Produits)

Synonymes: anticorps MIP-3ALPHA, anticorps CCL20, anticorps si:dkey-150o13.1, anticorps CKb4, anticorps LARC, anticorps MIP-3-alpha, anticorps MIP-3a, anticorps MIP3A, anticorps SCYA20, anticorps ST38, anticorps MIP-3A, anticorps MIP-3[a], anticorps Scya20, anticorps exodus-1, anticorps C-C motif chemokine ligand 20, anticorps chemokine (C-C motif) ligand 20b, anticorps chemokine (C-C motif) ligand 20, anticorps CCL20, anticorps ccl20b, anticorps Ccl20

Sujet: MIP-3α (also known as C-C motif chemokine 20, small-inducible cytokine A20, macrophage inflammatory protein 3 alpha, MIP-3-alpha, liver and activation-regulated chemokine, CC chemokine LARC and beta chemokine exodus-1) is a chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. MIP-3α inhibits proliferation of myeloid progenitors in colony formation assays and may be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. MIP-3α also possesses antibacterial activity against E.coli and S.aureus. MIP-3α is a secreted protein that is expressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels of expression are also seen in thymus, prostate, testis, small intestine and colon. C-terminal processed forms which lack 1, 3 or 6 amino acids are produced by proteolytic cleavage after secretion from peripheral blood monocytes.
Synonyms: MIP-3α , CCL20, C-C motif chemokine 20, small-inducible cytokine A20, macrophage inflammatory protein 3 alpha, MIP-3-alpha, liver and activation-regulated chemokine, CC chemokine LARC and beta chemokine exodus-1

ID gène: 6364, 4759076

UniProt: P78556

Pathways: Phosphorylation & l'infection par le SRAS-CoV-2