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IL-27 anticorps

IL27 Reactivité: Souris WB Hôte: Rat Monoclonal 3H12-F10 unconjugated
N° du produit ABIN1043836
  • Antigène Voir toutes IL-27 (IL27) Anticorps
    IL-27 (IL27) (Interleukin 27 (IL27))
    Reactivité
    • 56
    • 44
    • 11
    • 1
    Souris
    Hôte
    • 57
    • 20
    • 6
    • 2
    Rat
    Clonalité
    • 61
    • 24
    Monoclonal
    Conjugué
    • 50
    • 7
    • 6
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp IL-27 est non-conjugé
    Application
    • 60
    • 38
    • 18
    • 11
    • 7
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Specificité
    This product is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above. This antibody is specific for mouse and rat p28 protein. Cross-reactivity with IL-27 from other sources has not been determined.
    Attributs du produit
    Mouse IL-27/p28 Subunit, also known as Interleukin-30, is a member of the IL-12 family of cytokines. When combined with EBI3 (Epstein-Barr virus induced gene 3), the heterodimer formed is IL-27. Mouse p28 is a proinflammatory cytokine inducing immunomodulatory effects. Current research is underway to delineate specific biological functions.
    Purification
    purified
    Stérilité
    Sterile filtered
    Immunogène
    This Protein A purified monoclonal antibody was produced in rats by repeated immunizations with mature length recombinant mouse p28 protein (produced in E.coli) followed by hybridoma development.
    Immunogen Type: Recombinant Protein
    Clone
    3H12-F10
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product IL27 Anticorps primaire
  • Indications d'application
    IL-27 is expressed in activated antigen presenting cells including monocytes, endothelial cells, and dendritic cells, for example mouse CD4 splenocytes. This purified antibody has been tested for use in western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 26 KDa in size corresponding to the mature mouse p28 protein, a non-glycosylated polypeptide chain consisting of amino acids, by western blotting in appropriate cell lysate or extract.
    Commentaires

    Gene Name: IL27

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.0 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
    Date de péremption
    12 months
  • Murugaiyan, Mittal, Weiner: "Identification of an IL-27/osteopontin axis in dendritic cells and its modulation by IFN-gamma limits IL-17-mediated autoimmune inflammation." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 25, pp. 11495-500, (2010) (PubMed).

  • Antigène
    IL-27 (IL27) (Interleukin 27 (IL27))
    Autre désignation
    IL-27/p28 (IL27 Produits)
    Synonymes
    anticorps IL-27, anticorps IL-27A, anticorps IL27A, anticorps IL27p28, anticorps IL30, anticorps p28, anticorps RGD1561420, anticorps IL27, anticorps IL-27p28, anticorps Il30, anticorps interleukin 27, anticorps IL27, anticorps Il27
    Sujet
    Mouse IL-27/p28 Subunit, also known as Interleukin-30, is a member of the IL-12 family of cytokines. When combined with EBI3 (Epstein-Barr virus induced gene 3), the heterodimer formed is IL-27. Mouse p28 is a proinflammatory cytokine inducing immunomodulatory effects. Current research is underway to delineate specific biological functions.
    Synonyms: Interleukin-27 subunit alpha, IL-27 subunit alpha, IL-27-A cytokine, IL27-A, p28, IL-30
    ID gène
    246779
    NCBI Accession
    NP_663611
    UniProt
    Q8K3I6
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