Cobaye anti-Humain IgG (Heavy Chain) Anticorps (FITC)

N° du produit ABIN1045729

Détail du produit

Antigène: IgG

Épitope: Heavy Chain

Reactivité: Humain

Hôte: Cobaye

Clonalité: Polyclonal

Conjugué: FITC

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Purification: Caprylic Acid Ammonium Sulfate Precipitation

Immunogène: Human igg heavy chain

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.03 % Proclin 300, 50 % Glycerol, 0.01 M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze and thaw cycles. Product is photosensitive and should be protected from light.

Stock: -20 °C

Stockage commentaire: Shipped at 4 °C. Upon delivery aliquot and store at -24 °C or -84 °C.

Détail du antigène

Antigène: IgG

Abstract: IgG Produits

Classe de substances: Antibody

Sujet: Serum immunoglobulin IgG is the main component, accounting for total serum immunoglobulin content of 75 %. 40 ~ 50 % of the distribution in the serum, and the remaining distributed in the organization. Molecular weight of about 150 kDa. Human serum IgG mainly single, normal, including four subtypes of IgG, IgG1 accounted for its 60 ~ 70 %, IgG2 accounted for 15 ~ 20 %, IgG3 accounted for 5 ~ 10 %, IgG4 accounts for 1 ~ 7 %. These subtypes in the classical pathway of complement activation in the binding capacity varies. IgG mainly by the spleen and lymph nodes in the synthesis of plasma cells, is the only antibodies through the placenta, to prevent birth within weeks of infection play a significant role. Newborn infants after 3 months has been able to synthesize IgG, 2 ~ 3 years old has reached adult levels. Decreased gradually after the age of 40. IgG content of individual differences, the same individual under different conditions, fluctuations are also high. Antigen stimulation in the body produces most of the anti-bacterial, anti-virus, anti-toxin antibodies are IgG. Many autoantibodies, such as systemic lupus erythematosus LE factor, anti-thyroglobulin antibodies are IgG. IgG is the body's main anti-infection immune antibodies.

Poids moléculaire: 150 kDa