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RRAGA anticorps (AA 1-247)

RRAGA Reactivité: Humain ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1046027
  • Antigène Voir toutes RRAGA Anticorps
    RRAGA (Ras-Related GTP Binding A (RRAGA))
    Épitope
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-247
    Reactivité
    • 26
    • 12
    • 12
    • 1
    Humain
    Hôte
    • 26
    Lapin
    Clonalité
    • 25
    • 1
    Polyclonal
    Conjugué
    • 12
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp RRAGA est non-conjugé
    Application
    • 12
    • 11
    • 8
    • 3
    • 3
    • 3
    • 2
    • 1
    ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human Ras-related GTP-binding protein A protein (1-247AA)
    Isotype
    IgG
    Top Product
    Discover our top product RRAGA Anticorps primaire
  • Indications d'application
    Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid freeze and thaw cycles.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    RRAGA (Ras-Related GTP Binding A (RRAGA))
    Autre désignation
    RRAGA (RRAGA Produits)
    Synonymes
    anticorps FIP-1, anticorps FIP1, anticorps RAGA, anticorps 1300010C19Rik, anticorps AI255374, anticorps Raga, anticorps Ras related GTP binding A, anticorps Ras-related GTP binding A, anticorps RRAGA, anticorps Rraga
    Sujet

    Background: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form. In its active form participates in the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. May alternatively act as a cellular target for adenovirus E3-14.7K, an inhibitor of TNF-alpha functions, thereby affecting cell death.

    Aliases: Adenovirus E3 14.7 kDa-interacting protein 1 antibody, FIP-1 antibody, Rag A antibody, RagA antibody, Ras-related GTP-binding protein A antibody, RRAGA antibody, RRAGA_HUMAN antibody

    UniProt
    Q7L523
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