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PLA1A anticorps (C-Term)

PLA1A Reactivité: Humain, Rat WB, ELISA, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1077384
  • Antigène Voir toutes PLA1A Anticorps
    PLA1A (Phospholipase A1 Member A (PLA1A))
    Épitope
    • 7
    • 7
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 36
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Rat
    Hôte
    • 32
    • 4
    Lapin
    Clonalité
    • 35
    • 1
    Polyclonal
    Conjugué
    • 19
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PLA1A est non-conjugé
    Application
    • 25
    • 17
    • 13
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    Specificité
    At least three isoforms of PLA1A are known to exist, this antibody will detect all three isoforms.
    Purification
    Affinity chromatography purified via peptide column
    Immunogène
    PLA1A antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human PLA1A.
    Isotype
    IgG
    Top Product
    Discover our top product PLA1A Anticorps primaire
  • Indications d'application
    PLA1A antibody can be used for detection of PLA1A by Western blot at 1 - 2 μg/mL. For immunofluorescence start at 20 μg/mL.
    Commentaires

    (CT) Phospholipase A1 member A

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS containing 0.02 % Sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
    Stock
    4 °C
    Stockage commentaire
    PLA1A antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
    Date de péremption
    12 months
  • Antigène
    PLA1A (Phospholipase A1 Member A (PLA1A))
    Autre désignation
    PLA1A (PLA1A Produits)
    Synonymes
    anticorps PS-PLA1, anticorps PSPLA1, anticorps AA986889, anticorps Ps-pla1, anticorps Pspla1, anticorps wu:fi26h09, anticorps zgc:77160, anticorps AH, anticorps ARWH2, anticorps LAH2, anticorps LPDLR, anticorps PLA1B, anticorps mPA-PLA1, anticorps phospholipase A1 member A, anticorps lipase H, anticorps PLA1A, anticorps Pla1a, anticorps pla1a, anticorps CpipJ_CPIJ002492, anticorps CpipJ_CPIJ007883, anticorps LIPH
    Sujet
    PLA1A is a phospholipase that hydrolyzes fatty acids at the sn-1 position of phosphatidylserine and 1-acyl-2-lysophosphatidylserine. This secreted protein hydrolyzes phosphatidylserine (PS) in liposomes and can also hydrolyze PS in apoptotic cells and activate platelets where the resulting 2-acyl-lysophosphatidylserine acts as a lipid mediator for mast cells, T cells, and neural cells, suggesting that a major function of PLA1A may be the production of lysophospholipid mediators. PLA1A is upregulated in rat peripheral blood cells bearing long-term surviving cardiac allograft. PLA1A is also expressed in human THP-1-derived macrophages and this expression is upregulated in cells treated with lipopolysaccharide, a TLR4 ligand. This upregulation is inhibited with corticosteroids, which are often used at high dosages to suppress chronic allograft rejection.
    Synonyms: Phospholipase A1 member A, phosphatidylserine-specific phospholipase A1, PS-PLA1
    Poids moléculaire
    50 kDa
    ID gène
    51365
    NCBI Accession
    NP_056984
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