WIPI2 anticorps (N-Term)

N° du produit ABIN1077403

Détail du produit anti-WIPI2 anticorps

Antigène: WIPI2 (WD Repeat Domain, Phosphoinositide Interacting 2 (WIPI2))

Épitope: N-Term

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WIPI2 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: WIPI2 antibody is human and rat reactive. Multiple isoforms of WIPI2 are known to exist. WIPI2 antibody is predicted to not cross-react with WIPI1.

Purification: Affinity chromatography purified via peptide column

Immunogène: Rabbit polyclonal WIPI2 antibody was raised against a 17 amino acid peptide near the amino terminus of human WIPI2.

Isotype: IgG

Information d'application

Indications d'application: WIPI2 antibody can be used for detection of WIPI2 by Western blot at 1 - 2 μg/mL.

Commentaires:

(NT) WD repeat domain phosphoinositide interacting 2

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Stock: 4 °C/-20 °C

Stockage commentaire: WIPI2 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Date de péremption: 12 months

Détails sur WIPI2

Antigène: WIPI2 (WD Repeat Domain, Phosphoinositide Interacting 2 (WIPI2))

Autre désignation: WIPI2 (WIPI2 Produits)

Synonymes: anticorps ATG18B, anticorps Atg21, anticorps WIPI-2, anticorps 1110018O08Rik, anticorps 2510001I10Rik, anticorps WD repeat domain, phosphoinositide interacting 2 L homeolog, anticorps WD repeat domain, phosphoinositide interacting 2, anticorps wipi2.L, anticorps WIPI2, anticorps Wipi2

Sujet: WD repeat proteins play a role in many essential biologic functions, regulating the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. WIPI2, also known as ATG18B or ATG21, is a human homolog to yeast ATG18 and contains three WD repeats and has a 7-bladed propeller structure with a conserved motif that facilitates its interaction with other proteins. It is recruited to early autophagosomal structures along with Atg16L and ULK1 and is required for the formation of LC3-positive autophagosomes. Along with the highly related WIPI1, WIPI2 is found at the plasma membrane in addition to autophagosomal membranes.
Synonyms: WD repeat domain phosphoinositide interacting 2, WIPI-2, WD40 repeat protein interacting with phosphoinositides 2, WIPI49-like protein 2, ATG18B, ATG21, CGI-50

Poids moléculaire: 50 kDa

ID gène: 26100

NCBI Accession: NP_056425