TSPY1L (C-Term) anticorps

N° du produit ABIN1077408

Détail du produit

Antigène: TSPY1L

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: ELISA, Western Blotting (WB)

Specificité: TSPY1L antibody is human and mouse reactive. At least three isoforms of TSPY1 are known to exist, this antibody will detect only TSPY1L.

Purification: Affinity chromatography purified via peptide column

Immunogène: Rabbit polyclonal TSPY1L antibody was raised against a 20 amino acid peptide near the carboxy terminus of human TSPY1L.

Isotype: IgG

Information d'application

Indications d'application: TSPY1L antibody can be used for detection of TSPY1L by Western blot at 0.5 - 1 μg/mL.

Commentaires:

(CT) Testis specific protein Y-linked 1 large isoform

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Stock: 4 °C

Stockage commentaire: TSPY1L antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Date de péremption: 12 months

Détail du antigène

Antigène: TSPY1L

Sujet: Testis-specific protein on Y chromosome (TSPY1) is an ampliconic gene on the Y chromosome that has been associated with gonadoblastoma. Recent experiments have shown that in androgen-dependent testicular germ-cell tumors, TSPY1 can repress the androgen-bound androgen receptor (AR), a member of the nuclear steroid hormone receptor family that acts as a ligand-inducible transcription factor, suggesting that TSPY1 is a repressor of cell proliferation in germ-cell tumors and potentially in normal gonadal cells during early development. Two distinct isoforms of TSPY1, TSPY1L and TSPY1S, are known to exist.
Synonyms: Testis specific protein Y-linked 1 large isoform, TSPY, CT78, DYS14, pJA923

Poids moléculaire: 34 kDa

ID gène: 7258

NCBI Accession: NP_003299