Cyclin T1 anticorps (C-Term)

N° du produit ABIN1077437

Détail du produit anti-Cyclin T1 anticorps

Antigène: Cyclin T1 (CCNT1)

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cyclin T1 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Affinity chromatography purified via peptide column

Immunogène: Rabbit polyclonal CCNT1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human CCNT1.

Isotype: IgG

Information d'application

Indications d'application: CCNT1 antibody can be used for detection of CCNT1 by Western blot at 1 - 2 μg/mL.

Commentaires:

(CT) Cyclin T1

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Stock: 4 °C

Stockage commentaire: CCNT1 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Date de péremption: 12 months

Détails sur Cyclin T1

Antigène: Cyclin T1 (CCNT1)

Autre désignation: CCNT1 (CCNT1 Produits)

Synonymes: anticorps CG6292, anticorps Dmcyclin T, anticorps Dmel\\CG6292, anticorps ORE-14, anticorps P-TEFb, anticorps anon-74EFc, anticorps dT, anticorps p124, anticorps Cyclin-T1, anticorps ccnt, anticorps cyct1, anticorps CCNT, anticorps CYCT1, anticorps HIVE1, anticorps 2810478G24Rik, anticorps AI115585, anticorps CycT1, anticorps fi75b02, anticorps si:dkey-18f23.10, anticorps wu:fi75b02, anticorps Cyclin T, anticorps cyclin T1, anticorps cyclin T1 L homeolog, anticorps CycT, anticorps CCNT1, anticorps ccnt1, anticorps Ccnt1, anticorps ccnt1.L

Sujet: Cyclins function as regulators of CDK kinases and exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. The cyclin-T1 protein (CCNT1) belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. CCNT1 tightly associates with CDK9 kinase, and was found to be a major subunit of the transcription elongation factor p-TEFb. The kinase complex containing CCNT1 and the elongation factor can interact with, and act as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and was shown to be both necessary and sufficient for full activation of viral transcription. CCNT1 and its kinase partner were also found to be involved in the phosphorylation and regulation of the carboxy-terminal domain (CTD) of the largest RNA polymerase II subunit.
Synonyms: Cyclin T1, cyclin-T1, CDK9-associated C-type protein, human immunodeficiency virus type 1 expression 1, HIVE1

Poids moléculaire: 80 kDa (calculated)

ID gène: 904

NCBI Accession: NP_001231