RC3H1 anticorps (C-Term)
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- Antigène Voir toutes RC3H1 Anticorps
- RC3H1 (Ring Finger and CCCH-Type Domains 1 (RC3H1))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp RC3H1 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Specificité
- At least three isoforms of RC3H1 are known to exist, this antibody will detect all three isoforms.
- Purification
- Affinity chromatography purified via peptide column
- Immunogène
- Rabbit polyclonal RC3H1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human RC3H1.
- Isotype
- IgG
- Top Product
- Discover our top product RC3H1 Anticorps primaire
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- Indications d'application
- RC3H1 antibody can be used for detection of RC3H1 by Western blot at 1 - 2 μg/mL.
- Commentaires
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(CT) Ring finger and CCCH-type domains 1
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS containing 0.02 % Sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Stock
- 4 °C/-20 °C
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- Antigène
- RC3H1 (Ring Finger and CCCH-Type Domains 1 (RC3H1))
- Autre désignation
- RC3H1 (RC3H1 Produits)
- Synonymes
- anticorps RNF198, anticorps ROQUIN, anticorps RC3H1, anticorps si:dkey-192m14.4, anticorps 5730557L09Rik, anticorps Gm551, anticorps N28103, anticorps mKIAA2025, anticorps RGD1563512, anticorps rc3h1, anticorps ring finger and CCCH-type domains 1, anticorps ring finger and CCCH-type domains 1a, anticorps ring finger and CCCH-type zinc finger domains 1, anticorps RING CCCH (C3H) domains 1, anticorps ring finger and CCCH-type domains 1 L homeolog, anticorps RC3H1, anticorps rc3h1a, anticorps Rc3h1, anticorps rc3h1.L
- Sujet
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The ring finger protein RC3H1, also known as Roquin, is a highly conserved member of the RING type ubiquitin ligase protein family whose M199R mutation leads to the excessive production of follicular helper T cells and germinal centers in the sanroque strain of mice, a strain with excessive IL-21 production and high titers of autoantibodies. The complete loss of RC3H1 induces early death and immune deregulation but not autoimmunity in RC3H1-null mice, suggesting that the mutant RC3H1 is more disruptive to the immune system than its complete loss.
Synonyms: Ring finger and CCCH-type domains 1, ring finger protein 198, RNF198, roquin - Poids moléculaire
- 125 kDa
- ID gène
- 149041
- NCBI Accession
- NP_742068
- Pathways
- Ribonucleoprotein Complex Subunit Organization, Activated T Cell Proliferation
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