KREMEN1 anticorps (C-Term)

N° du produit ABIN1077451

Détail du produit anti-KREMEN1 anticorps

Antigène: KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KREMEN1 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: Three isoforms of KREMEN1 exists as a result of alternative splicing event.

Purification: Affinity chromatography purified via peptide column

Immunogène: Rabbit polyclonal KREMEN1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human KREMEN1.

Isotype: IgG

Information d'application

Indications d'application: KREMEN1 antibody can be used for detection of KREMEN1 by Western blot at 0.5 - 1 μg/mL.

Commentaires:

(CT) Kringle-containing protein marking the eye and the nose

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Stock: 4 °C/-20 °C

Détails sur KREMEN1

Antigène: KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))

Autre désignation: KREMEN1 (KREMEN1 Produits)

Synonymes: anticorps KREMEN1, anticorps krm1, anticorps kremen, anticorps kremem1, anticorps KREMEN, anticorps KRM1, anticorps AV002070, anticorps Kremen, anticorps Krm1, anticorps si:ct737139.1, anticorps si:dkeyp-7c9.1, anticorps kringle containing transmembrane protein 1, anticorps kringle containing transmembrane protein 1 S homeolog, anticorps KREMEN1, anticorps kremen1, anticorps Kremen1, anticorps kremen1.S

Sujet: Kremen (Kringle containing protein marking the eye and the nose) proteins are type I transmembrane proteins that contain extracellular kringle, WSC and CUB domains and an intracellular region without any conserved motifs. Kremens bind a subset of the secreted Dickkopf proteins (Dkk 1, 2, and 4) with high affinity to modulate the canonical Wnt signaling pathway that is transduced by the ternary receptor complex composed of Wnt, Frizzled, and the LDL receptor related protein 5/6 (LRP5/6) coreceptor. KREMEN1 is a receptor for the Dickkopf protein which blocks Wnt/beta catenin signaling. It is necessary to ensure normal spatial and temporal patterns of Wnt activity during developmental processes.
Synonyms: Kringle-containing protein marking the eye and the nose, Kringle containing transmembrane protein 1, KRM1, Dickkopf receptor

Poids moléculaire: 54 kDa

ID gène: 83999

NCBI Accession: NP_114434

Pathways: Signalisation WNT