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PTRF anticorps (C-Term)

PTRF Reactivité: Humain WB, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1077453
  • Antigène Voir toutes PTRF Anticorps
    PTRF (Polymerase I and Transcript Release Factor (PTRF))
    Épitope
    • 7
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 37
    • 15
    • 12
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 32
    • 5
    Lapin
    Clonalité
    • 35
    • 2
    Polyclonal
    Conjugué
    • 27
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PTRF est non-conjugé
    Application
    • 23
    • 12
    • 8
    • 7
    • 6
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Specificité
    At least three isoforms of PTRF are known to exist, this antibody detects all three isoforms. It is predicted to not cross-react with other members of the cavin family.
    Purification
    Affinity chromatography purified via peptide column
    Immunogène
    Rabbit polyclonal PTRF antibody was raised against a 19 amino acid peptide near the carboxy terminus of human PTRF.
    Isotype
    IgG
    Top Product
    Discover our top product PTRF Anticorps primaire
  • Indications d'application
    PTRF antibody can be used for detection of PTRF by Western blot at 0.5 - 1 μg/mL.
    Commentaires

    (CT) Polymerase I and transcript release factor

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS containing 0.02 % Sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
    Stock
    4 °C/-20 °C
  • Antigène
    PTRF (Polymerase I and Transcript Release Factor (PTRF))
    Autre désignation
    PTRF (PTRF Produits)
    Synonymes
    anticorps MGC53017, anticorps MGC89141, anticorps PTRF, anticorps fd20g07, anticorps ptrf, anticorps wu:fd20g07, anticorps zgc:162917, anticorps CAVIN, anticorps CAVIN1, anticorps CGL4, anticorps cavin-1, anticorps 2310075E07Rik, anticorps AW546441, anticorps Cav-p60, anticorps Cavin, anticorps caveolae associated protein 1 L homeolog, anticorps polymerase I and transcript release factor, anticorps caveolae associated protein 1, anticorps caveolae associated protein 1b, anticorps caveolae associated 1, anticorps cavin1.L, anticorps PTRF, anticorps cavin1, anticorps CAVIN1, anticorps cavin1b, anticorps Cavin1
    Sujet
    The polymerase I and transcript release factor (PTRF) enables the dissociation of paused ternary polymerase I transcription complexes from the 3' end of pre-rRNA transcripts, regulating rRNA transcription by promoting the dissociation of transcription complexes and the re-initiation of polymerase I on nascent rRNA transcripts. PTRF also localizes to caveolae at the plasma membrane and is thought to play a critical role in the formation of caveolae and the stabilization of caveolins, translocating from caveolae to the cytoplasm after insulin stimulation. PTRF is also thought to modify lipid metabolism and insulin-regulated gene expression. Mutations in this gene result in a disorder characterized by generalized lipodystrophy and muscular dystrophy.
    Synonyms: Polymerase I and transcript release factor, FKSG13, CAVIN, CAVIN1, CGL4, cavin-1, TTF-I interacting peptide 12
    Poids moléculaire
    43 kDa
    ID gène
    284119
    NCBI Accession
    NP_036364
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