CYP3A4 anticorps

N° du produit ABIN1106886

Détail du produit anti-CYP3A4 anticorps

Antigène: CYP3A4 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CYP3A4 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody recognizes Human CYP3A4.

Purification: Purified

Clone: 3H8

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS with 0.05 % Sodium Azide as preservative and 0.5 % protein stabilizer

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Détails sur CYP3A4

Antigène: CYP3A4 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4))

Autre désignation: CYP3A4 (CYP3A4 Produits)

Synonymes: anticorps CP33, anticorps CP34, anticorps CYP3A, anticorps CYP3A3, anticorps CYPIIIA3, anticorps CYPIIIA4, anticorps HLP, anticorps NF-25, anticorps P450C3, anticorps P450PCN1, anticorps MGC108372, anticorps CYP3A80, anticorps CYP3A4, anticorps CYP3A21, anticorps CYPIIIA21, anticorps CYP3A12, anticorps cytochrome P450 family 3 subfamily A member 4, anticorps cytochrome P450 family 3 subfamily A member 43, anticorps cytochrome P450 3A4, anticorps cytochrome P450, subfamily IIIA, polypeptide 4, anticorps cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4, anticorps cytochrome P450, family 3, subfamily A, polypeptide 4, anticorps CYP3A4, anticorps CYP3A43, anticorps PTRG_01782, anticorps PTRG_06060, anticorps cyp3a4

Sujet: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist, however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified.Synonyms: Albendazole monooxygenase, Albendazole sulfoxidase, CYP3A3, CYPIIIA3, CYPIIIA4, Cytochrome P450 3A3, Cytochrome P450 3A4, Cytochrome P450 HLp, Cytochrome P450 NF-25, Cytochrome P450-PCN1, Nifedipine oxidase, Quinine 3-monooxygenase, Taurochenodeoxycholate 6-alpha-hydroxylase

Poids moléculaire: 57.3 kDa

ID gène: 1576

Pathways: Steroid Hormone Biosynthesis