PDX1 anticorps

N° du produit ABIN1107766

Détail du produit anti-PDX1 anticorps

Antigène: PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PDX1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Specificité: Recognizes Insulin promoter factor 1 (PDX1)

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Purified

Clone: 2g12

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, 0.05 % Sodium Azide, 0.5 % protein stabilizer

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Détails sur PDX1

Antigène: PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))

Autre désignation: Insulin Promoter Factor 1 (PDX1 Produits)

Synonymes: anticorps GSF, anticorps IDX-1, anticorps IPF1, anticorps IUF1, anticorps MODY4, anticorps PDX-1, anticorps STF-1, anticorps ipf1, anticorps PDX1, anticorps IPF-1, anticorps Ipf1, anticorps Mody4, anticorps pdx-1, anticorps Idx1, anticorps Stf1, anticorps zgc:100874, anticorps XlHbox-8, anticorps xlhbox8, anticorps pancreatic and duodenal homeobox 1, anticorps pancreatic and duodenal homeobox 1 S homeolog, anticorps PDX1, anticorps pdx1, anticorps Pdx1, anticorps pdx1.S

Sujet: The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).Synonyms: GSF, Glucose-sensitive factor, IDX-1, IPF-1, IPF1, IUF-1, Insulin promoter factor 1, Insulin upstream factor 1, Islet/duodenum homeobox-1, PDX-1, PDX1, Pancreas/duodenum homeobox protein 1, STF-1, Somatostatin-transactivating factor 1

Poids moléculaire: 30.8 kDa

ID gène: 3651

Pathways: Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Hormone Transport, Carbohydrate Homeostasis, Chromatin Binding, Maintenance of Protein Location