Nubbin (NUB) anticorps

N° du produit ABIN1108497

Détail du produit

Antigène:

Nubbin (NUB)

Reactivité: Publilia modesta

Hôte: Lapin

Clonalité: Polyclonal

Application: Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)

Purification: Serum

Immunogène: Synthetic peptides derived from internal domain of the Publilia modesta Nubbin protein

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: Restore in distilled water

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Prior to reconstitution store the antibody at -20 °C. Store reconstituted antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer

Détail du antigène

Antigène:

Nubbin (NUB)

Autre désignation: Nubbin (NUB Antibody Extrait)

Sujet: Function: Specific down-regulator of the NEDD8 conjugation system. Recruits NEDD8, UBD, and their conjugates to the proteasome for degradation. Isoform 1 promotes the degradation of NEDD8 more efficiently than isoform 2. Tissue specificity: Widely expressed with lowest expression in the pancreas for isoform 1 and in leukocytes, liver, prostate and skeletal muscle for isoform 2. Sequence similarities: Contains 3 UBA domains. Cellular localization: Nucleus. Predominantly nuclear.