HCRTR1 anticorps (C-Term)

N° du produit ABIN1108529

Détail du produit anti-HCRTR1 anticorps

Antigène: HCRTR1 (Hypocretin (Orexin) Receptor 1 (HCRTR1))

Épitope: C-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HCRTR1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects Orexin Receptor 1+2 (C-term). No cross reactivity with other proteins.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat.

Purification: Immunogen affinity purified

Immunogène: Synthetic peptide corresponding to a sequence at the C-terminal of human Orexin Receptor .Remarks: Sequence is identical to the related mouse and rat sequence.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3

Agent conservateur: Sodium azide, Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur HCRTR1

Antigène: HCRTR1 (Hypocretin (Orexin) Receptor 1 (HCRTR1))

Autre désignation: Orexin Receptor Type 1 (HCRTR1 Produits)

Synonymes: anticorps OX1R, anticorps Ox1r, anticorps Hctr1, anticorps HCRTR1, anticorps hypocretin receptor 1, anticorps hypocretin (orexin) receptor 1, anticorps HCRTR1, anticorps Hcrtr1

Sujet: Orexins are endogeneous peptides that activate Orexin Receptor type 1 and type 2, two closely related G-protein coupled receptors. Orexins-A and -B are hypothalamic peptides derived from a precursor called preproorexin and affect the stimulation of food intake. They act on G protein receptors named orexin receptor-1 (OX1R) and orexin receptor-2 (OX2R), respectively.Stimulation of these receptors by orexins causes an increase in intracellular calcium levels in hypothalamic cells in vitro. In vivo, orexins control feeding and may also be involved in modulating sleep-wake cycles and other hypothalamic functions.Synonyms: HCRTR1, HCRTR2, Ox1r, Ox2r

ID gène: 3061

NCBI Accession: NP_001516

UniProt: O43613

Pathways: Feeding Behaviour