anticorps MGC82892, anticorps MGC146409, anticorps PIG3, anticorps tumor protein p53 inducible protein 3, anticorps tumor protein p53 inducible protein 3 S homeolog, anticorps Tp53I3, anticorps quinone oxidoreductase PIG3, anticorps TP53I3, anticorps tp53i3.S, anticorps tp53i3, anticorps tp53I3
Sujet
TP53I3 participates in the generation of reactive oxygen species (ROS). TP53I3 has low NADPH-dependent naphtoquinone reductase activity, with a preference for 1,2-naphtoquinone over 1,4-naphtoquinone. TP53I3 has low NADPH-dependent diamine reductase activity (in vitro). TP53I3 is localized to the cytoplasm and induced in primary, non-transformed and transformed cell cultures after exposure to genotoxic agents. TP53I3 microsatellite polymorphism is associated with differential susceptibility to cancer.Synonyms: PIG3, Quinone oxidoreductase PIG3, Tumor protein p53-inducible protein 3, p53-induced gene 3 protein