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SLC25A4 anticorps (N-Term)

SLC25A4 Reactivité: Rat WB, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN112625
  • Antigène Voir toutes SLC25A4 Anticorps
    SLC25A4 (Solute Carrier Family 25 (Mitochondrial Carrier, Adenine Nucleotide Translocator), Member 4 (SLC25A4))
    Épitope
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-11, N-Term
    Reactivité
    • 24
    • 12
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Rat
    Hôte
    • 24
    • 1
    Lapin
    Clonalité
    • 24
    • 1
    Polyclonal
    Conjugué
    • 11
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SLC25A4 est non-conjugé
    Application
    • 11
    • 8
    • 5
    • 5
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Séquence
    C-G-D-Q-A-L-S-F-L-K-D-F
    Specificité
    Reacts with Adenine Nucleotide Translocator 1 (ANT1).
    Réactivité croisée (Details)
    Species reactivity (expected):Mouse, Rabbit, Bovine and Chicken:Species reactivity (tested):Rat.
    Purification
    Affinity Chromatography on Protein G.
    Immunogène
    Synthetic peptide corresponding to the amino acids 1-11 of the native molecule Rat ANT1 conjugated to KLH
    Top Product
    Discover our top product SLC25A4 Anticorps primaire
  • Indications d'application
    ELISA: 1/500-1/2000. Western blot: Gives A peptide blockable duplet at 31/33 kD in rat heart mitochondria. Alsopart peptide blockable duplets at 38/48 and 66/70 kD.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    5.0 mg/mL (by OD280)
    Buffer
    PBS, pH 7.2 containing 0.09 % Sodium Azide as preservative.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    SLC25A4 (Solute Carrier Family 25 (Mitochondrial Carrier, Adenine Nucleotide Translocator), Member 4 (SLC25A4))
    Autre désignation
    SLC25A4 / ANT1 (SLC25A4 Produits)
    Synonymes
    anticorps 1, anticorps AAC1, anticorps ANT, anticorps ANT 1, anticorps ANT1, anticorps PEO2, anticorps PEO3, anticorps T1, anticorps AU019225, anticorps Ant1, anticorps ant, anticorps ant1, anticorps peo2, anticorps peo3, anticorps MANT1, anticorps SLC25A5, anticorps fa22e07, anticorps wu:fa22e07, anticorps zgc:77591, anticorps slc25a4, anticorps solute carrier family 25 member 4, anticorps solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4, anticorps adenine nucleotide translocator, anticorps solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4, anticorps solute carrier family 25 member 4 L homeolog, anticorps SLC25A4, anticorps Slc25a4, anticorps slc25a4, anticorps ANT1, anticorps slc25a4.L
    Sujet
    Adenine Nucleotide Translocase 1 (ANT1) catalyzes the exchange of ADP and ATP across the mitochondrial inner membrane. It is is a key component of the mitochondrial permeability transition pore (PT pore) complex and is also one of the most abundant proteins in the mitochondrion making up approximately 10 % of all mitochondrial proteins. Originally described as an ADP/ATP exchange factor, ANT1 has also been shown to be required for bax mediated apoptosis. This is effected by binding of bax to residues 105-156 of ANT1, presumably resulting in maintaining the PT pore in an open conformation. Interaction with bax is not required for ANT1 pro-apoptotic activity as overexpression of the ANT1 protein also leads to the induction of apoptosis.Synonyms: ADP/ATP translocase 1, ANT 1, Adenine nucleotide translocator 1, Solute carrier family 25 member 4
    ID gène
    85333
    NCBI Accession
    NP_445967
    UniProt
    Q05962
    Pathways
    Proton Transport, Dicarboxylic Acid Transport
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