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TNFSF9 anticorps (Extracellular Domain)

TNFSF9 Reactivité: Humain WB, ELISA, FACS, ICC Hôte: Souris Monoclonal 41B436 unconjugated
N° du produit ABIN1169256
  • Antigène Voir toutes TNFSF9 Anticorps
    TNFSF9 (Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))
    Épitope
    • 15
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Extracellular Domain
    Reactivité
    • 58
    • 30
    • 15
    Humain
    Hôte
    • 42
    • 19
    • 10
    • 2
    Souris
    Clonalité
    • 37
    • 33
    • 2
    Monoclonal
    Conjugué
    • 40
    • 6
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TNFSF9 est non-conjugé
    Application
    • 47
    • 36
    • 30
    • 13
    • 13
    • 8
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Specificité
    Recognizes extracellular domain of human CD137L.
     Réactivité croisée
    Humain
    Aucune reactivité croisée
    Souris
    Réactivité croisée (Details)
    Does not cross-react with mouse CD137L.
    Stérilité
    0.2 μm filtered
    Immunogène
    Recombinant human CD137L extracellular domain.
    Clone
    41B436
    Isotype
    IgG1
    Top Product
    Discover our top product TNFSF9 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
    Agent conservateur
    Without preservative
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.
    Date de péremption
    12 months
  • Gullo, Koh, Pang, Ho, Tan, Schwarz: "Inhibition of proliferation and induction of apoptosis in multiple myeloma cell lines by CD137 ligand signaling." dans: PLoS ONE, Vol. 5, Issue 5, pp. e10845, (2010) (PubMed).

  • Antigène
    TNFSF9 (Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))
    Autre désignation
    CD137L (TNFSF9 Produits)
    Synonymes
    anticorps TNFSF9, anticorps 4-1BB-L, anticorps 4-1BBL, anticorps AI848817, anticorps Cd137l, anticorps Ly63l, anticorps CD137L, anticorps TNF superfamily member 9, anticorps tumor necrosis factor (ligand) superfamily, member 9, anticorps Tnfsf9, anticorps LOC476729, anticorps TNFSF9
    Sujet
    The CD137 ligand (CD137L, 4-1BBL) is a member of the tumor necrosis factor (TNF) family. CD137L is a type II, transmembrane protein found on activated macrophages, dendritic cells and mature B cells. The interaction with its receptor 4-1BB induces recruitment of TNF receptor-associated factor 1 (TRAF1) and TRAF2 and interaction with the kinase p56lck. CD137 and CD137L have been reported to be involved in tumor rejection, apoptosis, anti-viral immunity, diabetes, in T and B cell co-stimulation and modulation of the immune response.
    UniProt
    P41273
    Pathways
    Activated T Cell Proliferation, Cancer Immune Checkpoints
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