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TNFSF9 anticorps (Tumor Necrosis Factor (Ligand) Superfamily, Member 9) (Extracellular Domain) Primary Antibody

TNFSF9 Reactivité: Humain ICC, FACS, ELISA, WB Hôte: Souris Monoclonal 41B436 unconjugated
Pubmed (1)
N° du produit ABIN1169256
$472.50
Plus shipping costs $45.00
100 μg
local_shipping Destination: Etats-Unis
Envoi sous 5 à 8 jours ouvrables
  • Antigène
    TNFSF9
    Épitope
    Extracellular Domain
    • 15
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Reactivité
    Humain
    • 66
    • 21
    • 5
    Hôte
    Souris
    • 55
    • 17
    • 10
    • 2
    Clonalité
    Monoclonal
    • 52
    • 31
    Conjugué
    Cet anticorp TNFSF9 est non-conjugé
    • 40
    • 8
    • 7
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Application
    Immunocytochemistry (ICC), Flow Cytometry (FACS), ELISA, Western Blotting (WB)
    • 45
    • 37
    • 33
    • 15
    • 13
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Specificité
    Recognizes extracellular domain of human CD137L.
     Réactivité croisée
    Humain
    Aucune reactivité croisée
    Souris
    Réactivité croisée (Details)
    Does not cross-react with mouse CD137L.
    Stérilité
    0.2 μm filtered
    Immunogène
    Recombinant human CD137L extracellular domain.
    Clone
    41B436
    Isotype
    IgG1
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
    Agent conservateur
    Without preservative
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.
    Date de péremption
    12 months
  • Gullo, Koh, Pang, Ho, Tan, Schwarz: "Inhibition of proliferation and induction of apoptosis in multiple myeloma cell lines by CD137 ligand signaling." dans: PLoS ONE, Vol. 5, Issue 5, pp. e10845, 2010 (PubMed).

  • Antigène
    TNFSF9
    Autre désignation
    CD137L (TNFSF9 Antibody Extrait)
    Synonymes
    TNFSF9, 4-1BB-L, 4-1BBL, AI848817, Cd137l, Ly63l, CD137L, TNF superfamily member 9, tumor necrosis factor (ligand) superfamily, member 9, Tnfsf9, LOC476729, TNFSF9
    Sujet
    The CD137 ligand (CD137L, 4-1BBL) is a member of the tumor necrosis factor (TNF) family. CD137L is a type II, transmembrane protein found on activated macrophages, dendritic cells and mature B cells. The interaction with its receptor 4-1BB induces recruitment of TNF receptor-associated factor 1 (TRAF1) and TRAF2 and interaction with the kinase p56lck. CD137 and CD137L have been reported to be involved in tumor rejection, apoptosis, anti-viral immunity, diabetes, in T and B cell co-stimulation and modulation of the immune response.
    UniProt
    P41273
    Pathways
    Activated T Cell Proliferation, Cancer Immune Checkpoints
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